Results 11 to 20 of about 80,074 (304)
Fatty Acid Profile and Desaturase Activity in Obesity: Roles, Mechanisms, and Clinical Relevance [PDF]
MetabolitesBackground: Obesity is a complex metabolic disease associated with several health complications, including insulin resistance, hypertension, and type 2 diabetes mellitus.
Michalina Banaszak +2 more
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Journal of Fungi, 2023 One of the most interesting groups of fatty acid derivates is the group of conjugated fatty acids from which the most researched include: conjugated linoleic acid (CLA) and conjugated linolenic acid (CLNA), which are associated with countless health ...
Jaroslav Hambalko +6 more
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Acyl-Lipid Δ6-Desaturase May Act as a First FAD in Cyanobacteria
Biomolecules, 2022 Fatty acid desaturases (FADs) play important roles in various metabolic and adaptive pathways in all living organisms. They represent a superfamily of oxygenases that introduce double bonds into the acyl chains of fatty acids (FAs).
Alexander Y. Starikov +3 more
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Frontiers in Plant Science, 2021 Trienoic fatty acids are essential constituents of biomembranes and precursors of jasmonates involved in plant defense responses. Two ω-3 desaturases, AtFAD7 and AtFAD8, synthetize trienoic fatty acids in the plastid.
María A. Luján +6 more
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Frontiers in Nutrition, 2023 IntroductionFatty acids (FAs) composition and desaturase activities can be altered in different metabolic conditions, but the adiposity-independent associations with clinical and biochemical indicators of cardiometabolic risk are still unclear.
Ivana Šarac +8 more
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Expression and Regulation of Δ5-Desaturase, Δ6-Desaturase, Stearoyl-Coenzyme A (CoA) Desaturase 1, and Stearoyl-CoA Desaturase 2 in Rat Testis [PDF]
Biology of Reproduction, 2003 In mammalian cells, essential polyunsaturated fatty acids (PUFAs) are converted to longer PUFAs by alternating steps of elongation and desaturation. In contrast to other PUFA-rich tissues, the testis is continuously drained of these fatty acids as spermatozoa are transported to the epididymis.
Thomas, Saether +4 more
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The Bacillus subtilis Acyl Lipid Desaturase Is a Δ5 Desaturase [PDF]
Journal of Bacteriology, 2003 ABSTRACT Bacillus subtilis was recently reported to synthesize unsaturated fatty acids (UFAs) with a double bond at positions Δ5, Δ7, and Δ9 (M. H. Weber, W. Klein, L. Muller, U. M. Niess, and M. A. Marahiel, Mol. Microbiol. 39:1321-1329, 2001).
Silvia G, Altabe +3 more
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A desaturase‐like protein from white spruce is a Δ9 desaturase [PDF]
FEBS Letters, 2002 Gymnospermae seed lipids are characterized by a high degree of desaturation, most having a Δ9 double bond. By degenerate polymerase chain reaction (PCR) we have isolated a white spruce (Picea glauca) cDNA clone that encodes an amino acid sequence sharing a high degree of homology with other putative plant acyl‐coenzyme A (CoA) Des9 desaturases.
Marillia, E. -F. +3 more
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Key Enzymes in Fatty Acid Synthesis Pathway for Bioactive Lipids Biosynthesis
Frontiers in Nutrition, 2022 Dietary bioactive lipids, one of the three primary nutrients, is not only essential for growth and provides nutrients and energy for life's activities but can also help to guard against disease, such as Alzheimer's and cardiovascular diseases, which ...
Xiao-Yan Zhuang +5 more
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Biomolecules, 2021 Stearoyl-CoA desaturase-1 (SCD1 or delta-9 desaturase, D9D) is a key metabolic protein that modulates cellular inflammation and stress, but overactivity of SCD1 is associated with diseases, including cancer and metabolic syndrome.
Anna B. Petroff +4 more
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