Results 1 to 10 of about 99,698 (261)
dsRNA-Seq: Identification of Viral Infection by Purifying and Sequencing dsRNA [PDF]
Viruses, 2019 RNA viruses are a major source of emerging and re-emerging infectious diseases around the world. We developed a method to identify RNA viruses that is based on the fact that RNA viruses produce double-stranded RNA (dsRNA) while replicating. Purifying and
Carolyn J. Decker +10 more
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Double-Stranded RNA Attenuates the Barrier Function of Human Pulmonary Artery Endothelial Cells [PDF]
, 2013 Circulating RNA may result from excessive cell damage or acute viral infection and can interact with vascular endothelial cells. Despite the obvious clinical implications associated with the presence of circulating RNA, its pathological effects on ...
A Shibamiya +60 more
core +14 more sources
Application of Double-stranded RNA (dsRNA) Produced by E. coli HT115 (DE3) and Vector L4440 in Reverse Genetics Studies in Insects [PDF]
Journal of Genetic Resources, 2023 RNA interference is a cellular process for regulating gene expression by double-stranded RNA (dsRNA). In the past two decades, this cellular process has been used as a tool for the temporary knockdown of gene expression to study gene function in reverse ...
Roohollah Abbasi
doaj +1 more source
Double-stranded RNAs are promising adjuvants for enhancing immunogenicity of vaccines
Журнал микробиологии, эпидемиологии и иммунобиологии, 2023 Background. The most effective way to prevent infectious diseases is vaccination. Adjuvants contribute to the optimization of the immune response of vaccines.
Olga N. Kaplina +3 more
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The Functional Mechanisms of Toll-Like Receptor 3 and Its Implications in Digestive System Tumors
Frontiers in Bioscience-Landmark, 2023 Toll-like receptor 3 (TLR3) is a prominent member of the Toll-like receptor (TLR) family and has the ability to recognize and bind intracellular double-stranded RNA (dsRNA).
Bin Han +7 more
doaj +1 more source
Инфекция и иммунитет, 2021 A search for new targeted therapeutic strategies based on examining immunopathogenetic mechanisms for emerging co-infections is relevant and may further contribute not only to optimizing choice of immunotropic drugs, but also to achieving positive ...
I. V. Nesterova +6 more
doaj +1 more source
Biological control of pathogenic fungi: Can mycoviruses play an important role? [PDF]
Journal of Central European Agriculture, 2022 In the past few years, huge economic and environmental losses have resulted by fungal pathogens in agriculture and food production worldwide. Fungal toxins also pose a threat for food production and animal health.
Tomáš Tonka +2 more
doaj +1 more source
SID-1 is a dsRNA-selective dsRNA-gated channel [PDF]
RNA, 2011 Systemic RNAi in Caenorhabditis elegans requires the widely conserved transmembrane protein SID-1 to transport RNAi silencing signals between cells. When expressed in Drosophila S2 cells, C. elegans SID-1 enables passive dsRNA uptake from the culture medium, suggesting that SID-1 functions as a channel for the transport of double-stranded RNA (dsRNA ...
Shih, Joseph D., Hunter, Craig
openaire +3 more sources
Effects of Nanoparticles on Double-Stranded RNA Stability in Corn Soil [PDF]
, 2018 Double-stranded RNA (dsRNA) can potentially be used as a pesticide because these molecules trigger an immune response called RNA interference (RNAi). If the expression of essential genes matching the dsRNA sequence are silenced, then the pest dies.
Reyanldo, Miriam +7 more
core +5 more sources
Cold Spring Harbor Perspectives in Biology, 2019 Long double-stranded RNAs (dsRNAs) are abundantly expressed in animals, in which they frequently occur in introns and 3' untranslated regions of mRNAs. Functions of long, cellular dsRNAs are poorly understood, although deficiencies in adenosine deaminases that act on RNA, or ADARs, promote their recognition as viral dsRNA and an aberrant immune ...
Daniel P, Reich, Brenda L, Bass
openaire +2 more sources