Results 91 to 100 of about 114,219 (358)
Next-generation sequencing of dsRNA is greatly improved by treatment with the inexpensive denaturing reagent DMSO. [PDF]
, 2019 dsRNA is the genetic material of important viruses and a key component of RNA interference-based immunity in eukaryotes. Previous studies have noted difficulties in determining the sequence of dsRNA molecules that have affected studies of immune function
Delwart, Eric +2 more
core
RNA interference in marine and freshwater sponges [PDF]
, 2011 Background: The marine sponge Tethya wilhelma and the freshwater sponge Ephydatia muelleri are emerging model organisms to study evolution, gene regulation, development, and physiology in non-bilaterian animal systems. Thus far, functional methods (i.e.,
Cieniewicz, Brandon +12 more
core +1 more source
Frontiers in Immunology, 2018 Viruses across genome types produce long dsRNA molecules during replication [viral (v-) dsRNA]. dsRNA is a potent signaling molecule and inducer of type I interferon (IFN), leading to the production of interferon-stimulated genes (ISGs), and a protective
Sarah J. Poynter +1 more
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2021 RNA interference (RNAi) is a valuable and revolutionary technology that has been widely applied in medicine and agriculture. The application of RNAi in various industries requires large amounts of low-cost double-stranded RNA (dsRNA).
Ruobing Guan +5 more
doaj +1 more source
Advanced Science, EarlyView.Japanese encephalitis virus (JEV) employs a cap‐independent (CI) translation strategy to evade host translational shutoff. During the shut‐off of host cellular canonical translation, DEAD‐box protein 3 (DDX3) bind to JEV UTRs to establish a closed‐loop architecture, and its interaction with poly(A)‐binding protein 1 (PABP1) to form DDX3/PABP1/eIF4G ...
Chenxi Li +13 more
wiley +1 more source
Scientific Reports, 2019 Mosquito-borne diseases are a major threat to human health and are responsible for millions of deaths globally each year. Vector control is one of the most important approaches used in reducing the incidence of these diseases.
Ramesh Kumar Dhandapani +3 more
semanticscholar +1 more source
Effects of pH on Double Stranded RNA Stability in European Corn Borer Nucleases [PDF]
, 2019 RNA interference (RNAI) is an immune response that can be exploited to make greener pesticides. It works by inciting suppression of a specific target gene using fed or injected dsRNA.
Biondi, Marie +4 more
core
Biotechnology and Bioengineering, EarlyView.A novel strategy for nuclear gene delivery in microalgae using a cell‐penetrating peptide (CPP) and nuclear localization signal (NLS) is described. The authors developed a triple nanocomplex of CPP, plasmid DNA, and SV40 NLS to enhance nuclear delivery in Chlamydomonas reinhardtii.
Eun Jeong Sim +10 more
wiley +1 more source
Predicting the DNA Conductance using Deep Feed Forward Neural Network Model [PDF]
arXiv, 2020 Double-stranded DNA (dsDNA) has been established as an efficient medium for charge migration, bringing it to the forefront of the field of molecular electronics as well as biological research. The charge migration rate is controlled by the electronic couplings between the two nucleobases of DNA/RNA.
arxiv
Spontaneous RNA condensation into nanoring structures [PDF]
arXiv, 2021 The effect of polyvalent molecular cations, such as spermine, on the condensation of DNA into very well-defined toroidal shapes have been well studied and understood. However, a great effort has been made trying to obtain similar condensed structures from either ssRNA or dsRNA, which the latter carries similar negative charge density as dsDNA, although
arxiv