Results 101 to 110 of about 114,219 (358)
The use of dsRNA to control insect pests via the RNA interference (RNAi) pathway is being explored by researchers globally. However, with every new class of insect control compounds, the evolution of insect resistance needs to be considered, and ...
Chitvan Khajuria+19 more
semanticscholar +1 more source
Suppression of Argonaute 2 Transcript Levels in Du182A Cells [PDF]
RNA interference (RNAi) uses double-stranded RNA (dsRNA) molecules to degrade and suppress the transcript level of a complementary mRNA target1.
Featherston, Kyah+2 more
core
RNA interference : a promising biopesticide strategy against the African sweetpotato weevil Cylas brunneus [PDF]
The African sweetpotato weevil Cylas brunneus is one of the most devastating pests affecting the production of sweetpotatoes, an important staple food in Sub-Saharan Africa. Current available control methods against this coleopteran pest are limited.
Bailey, Ana+7 more
core +1 more source
Mitochondrial dsRNA: A New DAMP for MDA5 [PDF]
The role of mitochondria as a signaling platform downstream of the RNA sensors RIG-I and MDA5 is well defined. Now, a recent study in Nature by Dhir et al. (2018) identifies mitochondrial dsRNA as an immunogenic ligand, adding another intriguing aspect to the role of mitochondria in innate immunity.
Veit Hornung+2 more
openaire +3 more sources
Spray-induced gene silencing (SIGS) can inhibit plant diseases by topical application of double- (dsRNA) or single-stranded (sRNA) RNA molecules onto plants to silence virulence-related pathogen genes. However, the on-field application of SIGS is limited
Yumeng Wang+6 more
doaj +1 more source
Recent Cutting‐Edge Technologies for the Delivery of Peptide Nucleic Acid
This review provides an overview of PNA cellular delivery methods, starting with traditional peptide‐based systems and progressing to advanced approaches using nanoparticles, liposomes, and calixarene. It highlights how these innovative strategies have opened the way for more effective and efficient PNA delivery, ultimately enhancing the potential for ...
Concetta Avitabile+4 more
wiley +1 more source
Knockdown of piRNA pathway proteins results in enhanced Semliki forest virus production in mosquito cells [PDF]
The exogenous siRNA pathway is important in restricting arbovirus infection in mosquitoes. Less is known about the role of the PIWI-interacting RNA pathway, or piRNA pathway, in antiviral responses. Viral piRNA-like molecules have recently been described
Donald, Claire L.+8 more
core +2 more sources
Viral nanomotors for packaging of dsDNA and dsRNA [PDF]
SummaryWhile capsid proteins are assembled around single‐stranded genomic DNA or RNA in rod‐shaped viruses, the lengthy double‐stranded genome of other viruses is packaged forcefully within a preformed protein shell. This entropically unfavourable DNA or RNA packaging is accomplished by an ATP‐driven viral nanomotor, which is mainly composed of two ...
Tae Jin Lee, Peixuan Guo
openaire +3 more sources
Analysis of Expression Patterns of PcABCG5 Gene in Penaeus chinensis Under Saline-Alkali Stress
Penaeus chinensis is one of the most economically important species in northern China. Strong market demand requires the expansion of aquaculture production capacity of P. chinensis.
Yalun LI+5 more
doaj +1 more source
A novel sustainable platform for scaled manufacturing of double-stranded RNA biopesticides
RNA interference (RNAi) represents one of the most conserved pathways evolved by eukaryotic cells for regulating gene expression. RNAi utilises non-translatable double-stranded RNA (dsRNA) molecules to sequester or degrade mRNA molecules gene.
Alison Obinna Nwokeoji+3 more
doaj +1 more source