Results 131 to 140 of about 74,293 (296)

Exogenous Application of IR-Specific dsRNA Inhibits Infection of Cucumber Green Mottle Mosaic Virus in Watermelon

Agronomy
Cucumber green mottle mosaic virus (CGMMV) represents a serious threat in the production of watermelon. Small RNAs facilitate a mechanism known as RNA interference (RNAi), which regulates gene expression.
Yanhui Wang, Liming Liu, Yongqiang Fan, Yanli Han, Zhiling Liang, Yanfei Geng, Fengnan Liu, Qinsheng Gu, Baoshan Kang, Chaoxi Luo   +9 more
doaj   +1 more source

Exogenous dsRNA Induces RNA Interference of a Chalcone Synthase Gene in Arabidopsis thaliana [PDF]

, 2022
Nikolay N. Nityagovsky, Konstantin V. Kiselev, Andrey R. Suprun, Alexandra S. Dubrovina   +3 more
openalex   +1 more source

Massive A-to-I RNA editing is common across the Metazoa and correlates with dsRNA abundance

Genome Biology, 2017
Adenosine to inosine (A-to-I) RNA editing is a post-transcriptional modification catalyzed by the ADAR (adenosine deaminase that acts on RNA) enzymes, which are ubiquitously expressed among metazoans.
Hagit T. Porath, B. Knisbacher, E. Eisenberg, E. Levanon   +3 more
semanticscholar   +1 more source

RIG-I and dsRNA-Induced IFNβ Activation

PLoS ONE, 2008
Except for viruses that initiate RNA synthesis with a protein primer (e.g., picornaviruses), most RNA viruses initiate RNA synthesis with an NTP, and at least some of their viral (ppp)RNAs remain unblocked during the infection. Consistent with this, most viruses require RIG-I to mount an innate immune response, whereas picornaviruses require mda-5.
Hausmann, Stéphane, Marq, Jean-Baptiste, Tapparel, Caroline, Kolakofsky, Daniel, Garcin, Dominique   +4 more
openaire   +5 more sources

Silencing of juvenile hormone‐related genes through RNA interference leads to molt failure and high mortality in the spongy moth

Insect Science, EarlyView.
The feasibility of using RNA interference to control the globally important quarantine pest, the spongy moth. Targeting genes related to JHs play an important role in the growth and development of insects. First, the open reading frames (ORFs) of Ldjhamt and Ldjheh were identified and characterized, and the target genes were cloned and double‐stranded ...
Wenzhuai Ji, Qing Xie, Xiaoxiao Chang, Juan Shi   +3 more
wiley   +1 more source

PACT prevents aberrant activation of PKR by endogenous dsRNA without sequestration

Nature Communications
The innate immune sensor PKR for double-stranded RNA (dsRNA) is critical for antiviral defense, but its aberrant activation by cellular dsRNA is linked to various diseases.
Sadeem Ahmad, Tao Zou, Jihee Hwang, Linlin Zhao, Xi Wang, Anton Davydenko, Ilana Buchumenski, Patrick Zhuang, Alyssa R. Fishbein, Diego Capcha-Rodriguez, Aaron Orgel, Erez Y. Levanon, Sua Myong, James Chou, Matthew Meyerson, Sun Hur   +15 more
doaj   +1 more source

Efficiency of Different Methods for dsRNA Delivery in Cotton Bollworm (Helicoverpa armigera)

Journal of Integrative Agriculture, 2014
RNAi trigged by dsRNA not only facilitates the development of molecular biology, but also initiates a new way for pest control by silence of fatal genes.
Jing YANG, Zhao-jun HAN
doaj   +1 more source

Sequence and expression analysis of potential spermatogenesis‐specific gene cognates in the Caribbean fruit fly, Anastrepha suspensa

Insect Science, EarlyView.
Abstract The sterile insect technique (SIT) is a highly effective biologically‐based method for the suppression of many insect pest populations. SIT efficacy could be improved by methods of male sterilization that avoid the use of irradiation that can result in diminished fitness and mating competitiveness.
Alfred M. Handler, Richard B. Furlong, Chao Chen, Daniel A. Hahn   +3 more
wiley   +1 more source

Research progress on immune mechanism and control strategy of dsRNA impurities in mRNA vaccine

Expert Review of Vaccines
Introduction Double-stranded RNA (dsRNA) is a key impurity of mRNA vaccines prepared by in vitro transcription (IVT) and is primarily transcribed by T7 RNA polymerase.
Xinjun Liu, Chaoying Hu, Qian He, Yu Bai, Xuanxuan Zhang, Zhihao Fu, Xiao Ma, Miao Xu, Zhenglun Liang, Qunying Mao   +9 more
doaj   +1 more source

DsiRNA‐mediated silencing of Ceratitis capitata transformer or transformer‐2 leads to masculinization of XX embryos and systemic gene silencing in ovaries

Insect Science, EarlyView.
We carried out functional studies using Dicer‐substrate small interfering RNAs (DsiRNAs), targeting the sex determination genes Cctransformer (Cctra) and Cctransformer‐2 (Cctra‐2) in the Mediterranean fruit fly (Ceratitis capitata). Microinjection of DsiRNAs into XX embryos (0‐1 h old) rapidly triggered the expression of male‐specific Cctra isoforms ...
Gennaro Volpe, Sarah Maria Mazzucchiello, Domenico De Falco, David Torrente, Stefania Liguori, Noemi Rosati, Dora Baccaro, Michela Mazzeo, Fulvio Bertolotto, Harshini Sangle, Ennio Giordano, Angela Carfora, Francesca Lucibelli, Marianna Varone, Paola Di Lillo, Hugo Diego Perdomo, Mariangela Bonizzoni, Serena Aceto, Marco Salvemini, Molly Duman‐Scheel, Giuseppe Saccone   +20 more
wiley   +1 more source