Results 131 to 140 of about 114,219 (358)
Recognition of Double-Stranded RNA and Regulation of Interferon Pathway by Toll-Like Receptor 10
Frontiers in Immunology, 2018 Toll-like receptor (TLR)-10 remains an orphan receptor without well-characterized ligands or functions. Here, we reveal that TLR10 is predominantly localized to endosomes and binds dsRNA in vitro at endosomal pH, suggesting that dsRNA is a ligand of ...
Suki Man-Yan Lee +6 more
doaj +1 more source
Insect Science, EarlyView.This study introduces a microinjection technique to deliver dsRNA into the hemolymph of first instar larval thrips (L1s) via the foreleg coxa, enhancing survival rates by minimizing internal tissue damage. Significant knockdown of V‐ATPase‐B, CYP3653A2, and ApoLp‐II/I was achieved, with silencing of CYP3653A2 or ApoLp‐II/I increasing larval mortality ...
Jinlong Han, Dorith Rotenberg
wiley +1 more source
Intronic Alus Influence Alternative Splicing [PDF]
PLoS Genet 2008 4(9): e1000204, 2008 Examination of the human transcriptome reveals higher levels of RNA editing than in any other organism tested to date. This is indicative of extensive double-stranded RNA (dsRNA) formation within the human transcriptome. Most of the editing sites are located in the primate-specific retrotransposed element called Alu.
arxiv
Molecular plant pathology, 2019 Summary CYP3RNA, a double‐stranded (ds)RNA designed to concomitantly target the two sterol 14α‐demethylase genes FgCYP51A and FgCYP51B and the fungal virulence factor FgCYP51C, inhibits the growth of the ascomycete fungus Fusarium graminearum (Fg) in ...
A. Koch +6 more
semanticscholar +1 more source
Natural antisense transcripts with coding capacity in Arabidopsis may have a regulatory role that is not linked to double-stranded RNA degradation [PDF]
, 2005 BACKGROUND: Overlapping transcripts in antisense orientation have the potential to form double-stranded RNA (dsRNA), a substrate for a number of different RNA-modification pathways.
Jen, C.H. +3 more
core +2 more sources
Insect Science, EarlyView.The role of 3 mitochondrial complex I gene in host expansion of Bactrocera tau was verified by CRISPR/Cas9 gene editing system. A stable homogenous strain (Btndufa7‐/‐) of B.tau was established after silencing Ndufa7. The reduced size of larvae and pupae of Ndufa7 knockout strain was first found.Then different levels of fitness and relative expression ...
Wei Shi +3 more
wiley +1 more source
Management of pest insects and plant diseases by non-transformative RNAi [PDF]
, 2019 Since the discovery of RNA interference (RNAi), scientists have made significant progress towards the development of this unique technology for crop protection.
Avila dos Santos, Ericmar +5 more
core +2 more sources
Frontiers in Cellular and Infection Microbiology, 2018 An important step in the initiation of the innate immune response to virus infection is the recognition of non-self, viral RNA, including double-stranded RNA (dsRNA), by cytoplasmic pattern recognition receptors (PRRs).
Elizabeth J. Mateer +2 more
doaj +1 more source
The transformer gene controls sexual development in Drosophila suzukii
Insect Science, EarlyView.The transformer gene plays a key role in the genetic pathway for sexual development in Drosophila suzukii Abstract The genetic network of sex determination in the model organism Drosophila melanogaster was investigated in great detail. Such knowledge not only advances our understanding of the evolution and regulation of sexual dimorphism in insects ...
Ying Yan +8 more
wiley +1 more source
Cellular origins of dsRNA, their recognition and consequences
Nature reviews. Molecular cell biology, 2021 Y. G. Chen, S. Hur
semanticscholar +1 more source