Results 151 to 160 of about 74,293 (296)

Evolutionary genomics of mycovirus-related dsRNA viruses reveals cross-family horizontal gene transfer and evolution of diverse viral lineages [PDF]

, 2012
Huiquan Liu, Yànpíng Fù, Jiǎtāo Xiè, Jiāsēn Chéng, Said A. Ghabrial, Guoqing Li, You‐Liang Peng, Xianhong Yi, Dàohóng Jiāng   +8 more
openalex   +1 more source

Structure of the RPAP3:TRBP interaction reveals an involvement of the HSP90/R2TP chaperone complex in dsRNA pathways [PDF]

, 2020
Yoann Abel, Christophe Charron, Valérie Bourguignon‐Igel, Marc Quinternet, Marie-Eve Chagot, Céline Verheggen, Christiane Branlant, Édouard Bertrand, Xavier Manival, Bruno Charpentier, Mathieu Rederstorff   +10 more
openalex   +1 more source

Evolutionary divergence and functional insights into the heteromeric cis‐prenyltransferase of Paramecium tetraurelia

The FEBS Journal, EarlyView.
Heteromeric cis‐prenyltransferases (CPT) are indispensable for dolichol synthesis and protein N‐glycosylation in most eukaryotes. The catalytic subunits are strongly conserved throughout evolution, in contrast to the evolutionarily variable accessory subunits. The POC1 protein from Paramecium tetraurelia is the smallest identified CPT‐accessory subunit
Agnieszka Onysk, Kamil Steczkiewicz, Mariusz Radkiewicz, Paweł Link‐Lenczowski, Przemysław Surowiecki, Karolina Sztompka, Kariona A. Grabińska, Jacek K. Nowak, Liliana Surmacz   +8 more
wiley   +1 more source

Newly identified properties of known pharmaceuticals and myxobacterial small molecules revealed by screening for autophagy modulators

The FEBS Journal, EarlyView.
Autophagy is a cellular degradation process involved in, for example, immune responses to pathogens and neurodegeneration. To identify modulators of autophagy, we developed a microscopy‐based screening assay and identified previously unknown autophagy‐modulating activities in known drugs and natural products from myxobacteria and fungi.
Janine Fichtner, Yan Yan Beer, H. G. Mauricio Ramm, Sabrina Mühlen, Frank Surup, Jennifer Herrmann, Toni Luise Meister, Stephanie Pfaender, Ursula Bilitewski, Mark Brönstrup, Rolf Müller, Manfred Wirth, Eeva‐Liisa Eskelinen, Ingo Schmitz   +13 more
wiley   +1 more source

Effect of dsRNA on Mesangial Cell Synthesis of Plasminogen Activator Inhibitor Type 1 and Tissue Plasminogen Activator [PDF]

, 2009
Markus Wörnle, Maximilian von Roeder, Matthias Sauter, Monika Merkle, Andrea Ribeiro   +4 more
openalex   +1 more source

First Evidence of Feeding-Induced RNAi in Banana Weevil via Exogenous Application of dsRNA [PDF]

, 2021
Henry Shaykins Mwaka, Olivier Christiaens, Priver Namanya, Jerome Kubiriba, Wilberforce Tushemereirwe, Godelieve Gheysen, Guy Smagghe   +6 more
openalex   +1 more source

SARS‐CoV‐2 nucleocapsid protein variants have differential RNA chaperone activity

The FEBS Journal, EarlyView.
The SARS‐CoV‐2 nucleocapsid (N) protein facilitates RNA annealing through its RBD–IDR2–CTD region, identifying it as a functional RNA chaperone. The Omicron BA.5 variant shows reduced chaperone activity compared to the Wuhan wild‐type protein. Although phosphorylation has no effect on wild‐type N, phosphomimetic modification of BA.5 N restores its RNA ...
Sabrina Babl, Julia M. Seidel, Fabian Kugler, Elisabeth Silberhorn, Anna Ludwig, Jonas Abel, Sophia Winklbauer, Niklas Schaub, Silvia Materna‐Reichelt, Kamran Honarnejad, Nataša Stojanović Gužvić, Gernot Längst   +11 more
wiley   +1 more source

Chemical Modifications in RNA: Elucidating the Chemistry of dsRNA-Specific Adenosine Deaminases (ADARs) [PDF]

, 2023
Herra G. Mendoza, Peter A. Beal
openalex   +1 more source

Characterization of dsRNA binding proteins through solubility analysis identifies ZNF385A as a dsRNA homeostasis regulator

Nature Communications
Double-stranded RNA (dsRNA) binding proteins (dsRBPs) play crucial roles in various cellular processes, especially in the innate immune response. Comprehensive characterization of dsRBPs is essential to understand the intricate mechanisms for dsRNA sensing and response.
Na Jiang, Hekun Yang, Yi Lei, Weida Qin, Huifang Xiong, Kuan Chen, Kunrong Mei, Gongyu Li, Xin Mu, Ruibing Chen   +9 more
openaire   +3 more sources

Requirement of group I lytic polysaccharide monooxygenase for turnover of chitinous cuticle during moulting in two forest pest beetles, Monochamus alternatus and Psacothea hilaris

Insect Molecular Biology, EarlyView.
Group I LPMO15‐1 cDNAs from two economically important forest insect pests, M. alternatus and P. hilaris, were cloned. MaLPMO15‐1 and PhLPMO15‐1 show a similar pattern of expression during late stages of development. RNAi for LPMO15‐1 causes failure of adult eclosion in both M. alternatus and P. hilaris.
Daehyeong Kim, Subbaratnam Muthukrishnan, Karl J. Kramer, Yasuyuki Arakane, Mi Young Noh   +4 more
wiley   +1 more source