Excess antisense RNA from infectious recombinant SV40 fails to inhibit expression of a transfected, interferon-inducible gene [PDF]
Kerr, I M, Kerr, S M, Stark, G R
core +1 more source
Induction of plant resistance to bean common mosaic virus (BCMV) via multiple applications of nanoparticle-conjugated dsRNA. [PDF]
Iralu N +6 more
europepmc +1 more source
Repeated Episodes of GPP Induced by Respiratory Infections Are Mediated by Loss‐of‐Function IFIH1
ABSTRACT Background Generalized pustular psoriasis (GPP) is a severe and recurrent autoinflammatory disease that can be induced by a variety of factors. At present, its etiology and pathogenesis have not yet been fully elucidated. Upper respiratory tract infections are the main predisposing factor in children with GPP, and the MDA5 protein encoded by ...
Yaqin Liu +5 more
wiley +1 more source
Adenosine-to-Inosine (A-to-I) RNA Editing by ADAR1 to Control RNA Sensing in Cardiovascular Disease. [PDF]
Weldy CS, Li JB, Quertermous T.
europepmc +1 more source
RNA‐Based Therapies for Inherited Metabolic Disorders
ABSTRACT Inherited metabolic disorders (IMDs) are a diverse and complex group of genetic conditions resulting from deficiencies in enzymes, transporters, or cofactors. These deficiencies lead to metabolic dysfunction and severe clinical consequences. Despite significant progress in understanding their molecular basis, treatment options remain limited ...
Reddy Sreekanth Vootukuri +5 more
wiley +1 more source
Cellular uptake of extracellular dsRNA is tissue-dependent in insects. [PDF]
Shi X +9 more
europepmc +1 more source
RNAi-mediated knockdown of the poultry red mite cathepsin D-1 impacts haemoglobin digestion. [PDF]
Chen W +9 more
europepmc +1 more source
RNA Regulatory Networks: Key Hubs in the Panorama of Cancer and Emerging Therapeutic Targets
RNA regulatory networks play a crucial role in the initiation and progression of cancer through various modes of RNA interactions. Notably, circulating RNAs have emerged as potential biomarkers, while targeted interventions in RNA regulatory networks facilitate precise therapeutic strategies. ABSTRACT Cancer is a global health challenge. The initiation
Xuan Yin +9 more
wiley +1 more source
Control Strategies of Plant Viruses Using Spray-Induced Gene Silencing. [PDF]
Choi SK +4 more
europepmc +1 more source
Varroa destructor mites exposed to dsRNA specific in sequence to a V. destructor calmodulin gene significantly effected gene expression of adult female mites sampled 5 days after entering a honey bee brood cell to reproduce. Significantly down‐regulated genes included Calmodulin and were associated with calcium ion binding and embryo developmental ...
Zoe E Smeele +10 more
wiley +1 more source

