Results 81 to 90 of about 114,219 (358)

Identification, Molecular Characterization, and Biology of a Novel Quadrivirus Infecting the Phytopathogenic Fungus Leptosphaeria biglobosa. [PDF]

open access: yes, 2018
Here we report the molecular characterisation of a novel dsRNA virus isolated from the filamentous, plant pathogenic fungus Leptosphaeria biglobosa and known to cause significant alterations to fungal pigmentation and growth and to result in ...
Coutts, Robert   +3 more
core   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

open access: yesFEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik   +2 more
wiley   +1 more source

Effects of Nanoparticles on Double-Stranded RNA Stability in Moth Hemolymph [PDF]

open access: yes, 2018
RNA interference (RNAi) is an immune response in which double-stranded RNA (dsRNA) suppresses a target gene. By designing dsRNA to target genes that are necessary for life, dsRNA can potentially be used as an insecticide.
Cooper, Anastasia   +7 more
core  

Opportunities in Therapeutic mRNA Stabilization: Sequence, Structure, Adjuvants and Vectors

open access: yesAdvanced Therapeutics, EarlyView.
Current mRNA lipid nanoparticles rely on cold storage, which increases the cost and reduces access to the vaccines. As mRNA expands to other clinical opportunities, better methods to stabilize the medicines during shipping, storage, and delivery are needed.
Joshua A. Choe   +4 more
wiley   +1 more source

Identification and application of exogenous dsRNA confers plant protection against Sclerotinia sclerotiorum and Botrytis cinerea

open access: yesScientific Reports, 2018
Sclerotinia sclerotiorum, the causal agent of white stem rot, is responsible for significant losses in crop yields around the globe. While our understanding of S.
Austein G. Mcloughlin   +8 more
semanticscholar   +1 more source

Investigation of Virus Diseases and Molecular Detection of Little Cherry Virus 1 on Cherry Plants at Niğde Province

open access: yesTurkish Journal of Agriculture: Food Science and Technology, 2019
To investigate the virus infections of sour and sweet cherries, various locations of Niğde province were examined during 2017. Ninety sweet and sour cherry leaf samples showing suspicious virus symptoms were collected and screened with virus-specific ...
Quratul Ain Sajid, Eminur Elçi
doaj   +1 more source

Mechanisms of length-dependent recognition of viral double-stranded RNA by RIG-I

open access: yesScientific Reports, 2023
Retinoic acid-inducible gene I (RIG-I) is the most front-line cytoplasmic viral RNA sensor and induces antiviral immune responses. RIG-I recognizes short double-stranded (dsRNA) ( 500 bp) to trigger antiviral signaling.
Jung Hyun Im   +6 more
doaj   +1 more source

Neophytadiene, a Plant Specialized Metabolite, Mediates the Virus‐Vector‐Plant Tripartite Interactions

open access: yesAdvanced Science, EarlyView.
Tomato chlorosis virus (ToCV) infection induces production of neophytadiene, a volatile resulting from chlorophyll degradation that is highly attractive to whiteflies. OBP2, an odorant‐binding protein from insect vector B. tabaci, exhibits a strong binding affinity for neophytadiene.
Xiao‐bin Shi   +14 more
wiley   +1 more source

Function of HNRNPC in breast cancer cells by controlling the dsRNA‐induced interferon response

open access: yesEMBO Journal, 2018
Elevated expression of RNA binding protein HNRNPC has been reported in cancer cells, while the essentialness and functions of HNRNPC in tumors were not clear.
Yusheng Wu   +9 more
semanticscholar   +1 more source

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