Glycogen synthase kinase 3 (GSK-3) has been linked to regulation of kinesin-dependent axonal transport in squid and flies, and to indirect regulation of cytoplasmic dynein. We have now found evidence for direct regulation of dynein by mammalian GSK-3β in
Alexander, Michael +4 more
core +1 more source
Regulation of cytoplasmic dynein by LIS1 [PDF]
Cytoplasmic dynein-1 (dynein) is a microtubule-based motor protein that plays a central role in organizing the contents of the cell during both interphase and cell division.
Nguyen, Kendrick Hoan-Vi
core
Nuclei on the move: LINC complex-dependent and -independent mechanisms of nuclear migration in development. [PDF]
Gümüşderelioğlu S +2 more
europepmc +1 more source
Structural and ensemble-based mechanistic insights into cytoplasmic dynein-1. [PDF]
Kumawat A.
europepmc +1 more source
A homozygous splice-site variant in <i>ZMYND10</i> causes primary ciliary dyskinesia with primary infertility in a Chinese family. [PDF]
He J +8 more
europepmc +1 more source
Functional Characterization of a Novel Homozygous <i>DNAH5</i> Single-Nucleotide Intronic Deletion in a Consanguineous Portuguese Family with Primary Ciliary Dyskinesia. [PDF]
Hilário C +11 more
europepmc +1 more source
Investigating the Function of C‑Terminal Tails of Human Tubulin Isotypes in the Motility Regulation of Cytoplasmic Dynein. [PDF]
Garg J +3 more
europepmc +1 more source
Axonal Transport Deficits in Parkinson's Disease: Insights from Neurotoxin, Genetic, and Sporadic Models. [PDF]
Wang X, Liu Z, Smith WW.
europepmc +1 more source
The roles of dynein and dynein accessory proteins in T cell effector functions
textT cell effector functions depend on focused secretion. This is accomplished by secretory vesicle (SV) clustering around the microtubule organizing center (MTOC) and MTOC translocation to the specialized site of cell-cell contact - the immunological ...
Christian, Laura Manno
core
High level dynein impairs mitochondrial distribution and differentiation of rhabdomyosarcoma cells. [PDF]
Ke TL, Chen L.
europepmc +1 more source

