Results 141 to 150 of about 41,114 (259)
The Role and Mechanism of Incretins in Gynaecologic Diseases
Endocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.This review outlines the mechanisms of incretins in polycystic ovary syndrome, endometriosis and gynaecological cancers, highlighting the translational potential of incretin‐based therapies for metabolic‐associated gynaecological disorders. ABSTRACT Background Obesity is a major global public health concern closely linked to the development and ...
Jiayu Yan +10 more
wiley +1 more source
Food Frontiers, Volume 7, Issue 5, September 2026.In a 120‐day randomized trial, CLA‐enriched fermented dairy remodeled the gut microbiota and rewired host metabolic pathways in patients with MASLD. These changes were accompanied by reductions in ALT, total cholesterol, creatinine, and hs‐CRP, supporting a microbiota‐mediated dietary strategy for metabolic and liver health.
Fei Mi +13 more
wiley +1 more source
Glia, Volume 74, Issue 9, September 2026.Dual‐color STORM resolves the precise architecture and protein distributions within hippocampal astrocytes at the nanoscale. Identification of a sparse but specific MAGL pool in CA1 astrocytic processes. Astrocytic MAGL is not synapse‐associated, suggesting a synapse‐independent role.
Miklós Zöldi, István Katona
wiley +1 more source
Glia, Volume 74, Issue 9, September 2026.Proinflammatory activation reorganizes microglial A2A and CB2 receptors, promoting their incorporation into stable heteromers and blocking agonist‐induced redistribution. The results reveal those heteromers as potential therapeutic targets in inflammatory contexts.
Rafael Franco +4 more
wiley +1 more source
The Role of Hippocampal Interneuron Migration in Neurodevelopmental Disorders: A Systematic Review
Hippocampus, Volume 36, Issue 5, September 2026.ABSTRACT Hippocampal abnormalities are frequently associated with neurodevelopmental disorders as interneurons are crucial in establishing the network connectivity of neurons. This systematic review analyzed primary literature with a focus on aberrant hippocampal interneuron migration as an etiology for neurodevelopmental disorders, summarizing the ...
M. A. C. Till +3 more
wiley +1 more source
Human Psychopharmacology: Clinical and Experimental, Volume 41, Issue 5, September 2026.ABSTRACT Objective This review critically examines psilocybin, with particular emphasis on its pharmacokinetics and pharmacodynamics, including its serotonergic, neuroplastic, and anti‐inflammatory mechanisms. It integrates historical context, preclinical and clinical evidence, and evaluates emerging therapeutic potential, safety, microdosing practices,
José Norberto Vásquez‐Bonilla
wiley +1 more source
Design and synthesis of Heterocyclic Compounds as CB2 Selective Agoists [PDF]
, 2008 Cannabinoids are present in Indian hemp, Cannabis sativa L., and have been used since antiquity as medicinal agents(1). Interest in cannabinoid pharmacology has rapidly increased since the discovery of the endocannabinoid system (ECS), which includes ...
BENETTI, VERONICA
core
The Intraplantar CFA Inflammatory Pain Model Incompletely Captures Pain Comorbidities Across Sexes
Journal of Neuroscience Research, Volume 104, Issue 9, September 2026.This study provides a standardized investigation into nociceptive and anxiety‐like behaviors in the intraplantar Complete Freund's Adjuvant (CFA) inflammatory pain model in both male and female mice across a 3‐week period. We found robust changes in mechanical hypersensitivity and cold allodynia but did not see any changes in anxiety‐like behaviors ...
Caitlin E. Fenech +2 more
wiley +1 more source
ROLE OF THE ENDOCANNABINOID SYSTEM IN SPERMATOGENESIS: SYSTEMS BIOLOGY APPROACH
, 2014 The spermatogenesis is a complex process that requires the differentiation of male gametes within the male genital tract. It involves a series of cellular events including mitosis, meiosis, cell migration, apoptosis, and differentiation of diploid germ
BARBONI, Barbara +4 more
core +1 more source