Results 131 to 140 of about 41,114 (259)

Perinatal lead (Pb) exposure and alterations to amyloid beta and metabolic profiles in the brain

Alzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract INTRODUCTION Developmental neurotoxicant exposures (e.g., lead [Pb]) are suspected contributors to dementia. Dementia is characterized by amyloid beta (Aβ) plaques and dysregulated metabolism. To better understand the relationship between environment and dementia risk, we assessed the impact of perinatal Pb exposure on dementia‐related ...
Rachel K. Morgan, Evelyn K. Matei, Junru Pan, Tomoko Ishikawa, Katelyn M. Polemi, Ingrid Bergin, Sean P. Ferris, Hao Wang, Dana C. Dolinoy, Kelly M. Bakulski, Justin A. Colacino   +10 more
wiley   +1 more source

Cannabinoid CB(1) receptor stimulation affords neuroprotection in MPTP-induced neurotoxicity by attenuating S100B up-regulation in vitro.

, 2007
In this study, we investigated the mechanism of S100B neurotoxicity and the effect of cannabinoids, in C6 cells treated with 1-methyl-4-phenyl 1,2,3,6 tetrahydropyridine (MPTP) and co-cultured with differentiated PC12 cells.
MARZO V, BISOGNO T, IUVONE T, DI, DE FILIPPIS D, ENDOCANNABINOID RESEARCH GROUP, SCUDERI, CATERINA, STEARDO, LUCA, PETROSINO S, ESPOSITO, GIUSEPPE   +9 more
core   +1 more source

Cannabinoids and monoaminergic system: implications for learning and memory

Frontiers in Neuroscience
Cannabinoids and the endocannabinoid system (ECS) have been intensively studied for their neuroregulatory roles in the central nervous system (CNS), especially in regulating learning and memory.
Sha Zhao, Sha Zhao, Zhao-Liang Gu, Ya-Nan Yue, Ya-Nan Yue, Xia Zhang, Yuan Dong   +6 more
doaj   +1 more source

Comparing the Impact of Tetrahydrocannabinol on 30‐Day Readmission Rates and Hospital Length of Stay in Patients With Depression

Brain and Behavior, Volume 16, Issue 9, September 2026.
Among patients hospitalized for major depressive disorder, a positive THC urine drug screen was not independently associated with 30‐day psychiatric readmission or hospital length of stay. These findings suggest that patient factors beyond THC exposure may have a greater influence on hospitalization outcomes.
Mohammed E. Khedr, Yunjin Lee, Muhammed A. Mirza, Humberto Jimenez, Daniel Greer   +4 more
wiley   +1 more source

NG2‐Glia in Central Nervous System Following Injury: From Pathological Involvement to Repair Potential

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
Following CNS injury, NG2‐glia display distinct functional phases. In the early stage, NG2‐glia are rapidly activated, proliferate, migrate to the lesion site and secrete CSPGs, which form a chemical and physical barrier that inhibits axonal regeneration.
Yunyun Cai, Xin Shen, Ming Li, Junjie Li, Gang Chen   +4 more
wiley   +1 more source

Cannabinoid‐Inspired Fluorescent Boroisoquinolines for CB1 Receptor Imaging

ChemPhotoChem, Volume 10, Issue 9, September 2026.
A cannabinoid‐inspired fluorescent boroisoquinoline, a low‐micromolar partial agonist of the human CB1 receptor, enabled imaging of CB1 receptors by confocal microscopy in live cells. The intrinsic fluorescence of our probe provides a unique opportunity for CB1 imaging while keeping receptor structure and pharmacology similar to that observed with ...
Dénes Szepesi Kovács, Csilla Nierner, Bettina Szepesi Kovács, Attila Lehotzky, Edina Szűcs, András Dávid Tóth, Dóra Judit Kiss, László Hunyady, György M. Keserű, Péter Ábrányi‐Balogh   +9 more
wiley   +1 more source

The evolution and comparative neurobiology of endocannabinoid signalling [PDF]

, 2012
Elphick, MR
core   +1 more source

Cannabinoids and the endocannabinoid system in liver diseases

Cannabinoids are biologically active substances acting via feedback-coupled CB1 and CB2 receptors. Their expression in myofibroblasts and liver endothelial cells is reported to be elevated in chronic liver diseases. The effect of CB1 receptor stimulation
Anna Parfieniuk-Kowerda, Aleksandra Andrzejuk, Robert Flisiak, Diana Martonik, Aleksander Tarasik   +4 more
core   +1 more source

The Endocannabinoid System and Neurogenesis in Health and Disease

, 2007
The endocannabinoid system exerts an important neuromodulatory function in different brain areas and is also known to be involved in the regulation of neural cell fate.
Guzmán Pastor, Manuel, Galve Roperh, Ismael, Aguado Sánchez, Tania, Palazuelos Diego, Javier   +3 more
core   +1 more source

Circulating Endocannabinoids in Canine Cutaneous Mast Cell Tumor

Animals
A cutaneous mast cell tumor (cMCT) is among the most common tumors in dogs. Endocannabinoids (eCBs) belong to the endocannabinoid system (ECS), which involves also cannabinoid receptors and an enzymatic system of biosynthesis and degradation.
Valentina Rinaldi, Fabiana Piscitelli, Andrea Boari, Roberta Verde, Paolo Emidio Crisi, Tiziana Bisogno   +5 more
doaj   +1 more source