Results 111 to 120 of about 37,091 (247)

Efficacy of omega‐3 fatty acids as a functional food: a multifaceted approach to health reinforcement

Journal of the Science of Food and Agriculture, Volume 106, Issue 8, Page 4521-4549, June 2026.
Abstract Omega‐3 fatty acids (omega‐3s) are polyunsaturated fatty acids linked with numerous health benefits. Omega‐3s exhibit multifaceted activities through various mechanisms. Eicosapentaenoic acid (EPA) alleviates oxidative stress by lowering reactive oxygen species and improving oxidative stress in brain tissues and acts against neurodegenerative ...
Md Faruque Ahmad, Abdulrahman A Alsayegh, Anjum Khanam, Awais Ahmed, António Raposo, Farkad Bantun, Md Zeyaullah, Ahmad O Babalghith, Abdullah F Aldairi, Boshra Mozaffar, Mohammed F Bajahzer, Mohamed H Abdelrahman, Mohammad Intakhab Alam   +12 more
wiley   +1 more source

Chemical synthesis, pharmacological characterization, and possible formation in unicellular fungi of 3-hydroxy-anandamide1

Journal of Lipid Research, 2009
The fungal pathogen Candida albicans transforms arachidonic acid (AA) into 3-hydroxyarachidonic acid [3(R)-HETE], and we investigated if its nonpathogenic and 3(R)-HETE-producing close relative, Dipodascopsis uninucleata, could similarly transform the ...
L. De Petrocellis, R. Deva, F. Mainieri, M. Schaefer, T. Bisogno, R. Ciccoli, A. Ligresti, K. Hill, S. Nigam, G. Appendino, V. Di Marzo   +10 more
doaj   +1 more source

The Endocannabinoid System and Neurogenesis in Health and Disease

, 2007
The endocannabinoid system exerts an important neuromodulatory function in different brain areas and is also known to be involved in the regulation of neural cell fate.
Guzmán Pastor, Manuel, Galve Roperh, Ismael, Aguado Sánchez, Tania, Palazuelos Diego, Javier   +3 more
core   +1 more source

Transcriptome assemblies for two drug‐type cannabis chemotypes by long‐read RNA sequencing

The Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Cannabis sativa has undergone over 10,000 years of domestication, resulting in extensive genetic and phenotypic diversity among cultivated chemotypes. Increased medical and recreational use of specialized metabolites accumulating in cannabis glandular trichomes—primarily the cannabinoids ∆9‐tetrahydrocannabinol (THC) and cannabidiol (CBD)—has ...
Oliver Berkowitz, Ricarda Jost, Sophia Ng, Antony Bacic, James Whelan, Mathew G. Lewsey   +5 more
wiley   +1 more source

Identification of Novel Predictive Biomarkers for Endometrial Malignancies: N-Acylethanolamines

Frontiers in Oncology, 2019
Objective: To identify new biochemical markers for endometrial cancer (EC). Recent evidence suggests that members of the endocannabinoid system (N-acylethanolamines) that bind to and activate receptors that are dysregulated in EC are involved in this ...
Thangesweran Ayakannu, Thangesweran Ayakannu, Anthony H. Taylor, Anthony H. Taylor, Timothy H. Marczylo, Timothy H. Marczylo, Mauro Maccarrone, Justin C. Konje, Justin C. Konje   +8 more
doaj   +1 more source

The endocannabinoid system, energy expenditure and thermogenesis

, 2008
Discussion about the endocannabinoid system, energy expenditure and ...
VICENNATI, VALENTINA, Bellocchio L, Cervino C, PAGOTTO, UBERTO, PASQUALI, RENATO   +4 more
core  

Release of anandamide from blood cells [PDF]

, 2006
Background: Endogenous ligands of cannabinoid receptors ( endocannabinoids), in particular anandamide ( arachidonylethanolamide), have been recognized as being of crucial importance in a variety of physiological functions.
Storr, Martin, Huber, Erasmus, Azad, Shahnaz C., Schelling, Gustav, Vogeser, Michael, Hauer, Daniela   +5 more
core   +1 more source

Prophylactic Palmitoylethanolamide Prolongs Survival and Decreases Detrimental Inflammation in Aged Mice With Bacterial Meningitis

Frontiers in Immunology, 2018
Easy-to-achieve interventions to promote healthy longevity are desired to diminish the incidence and severity of infections, as well as associated disability upon recovery.
Ev Christin Heide, Laura Bindila, Julia Maria Post, Dörthe Malzahn, Beat Lutz, Jana Seele, Roland Nau, Roland Nau, Sandra Ribes   +8 more
doaj   +1 more source

Cannabinoid CB(1) receptor stimulation affords neuroprotection in MPTP-induced neurotoxicity by attenuating S100B up-regulation in vitro.

, 2007
In this study, we investigated the mechanism of S100B neurotoxicity and the effect of cannabinoids, in C6 cells treated with 1-methyl-4-phenyl 1,2,3,6 tetrahydropyridine (MPTP) and co-cultured with differentiated PC12 cells.
MARZO V, BISOGNO T, IUVONE T, DI, DE FILIPPIS D, ENDOCANNABINOID RESEARCH GROUP, SCUDERI, CATERINA, STEARDO, LUCA, PETROSINO S, ESPOSITO, GIUSEPPE   +9 more
core   +1 more source

Adolescent cannabis use and psychological distress from 2013 to 2023: A population‐based study in Ontario, Canada

Addiction, Volume 121, Issue 6, Page 1495-1507, June 2026.
Abstract Background and aims Epidemiologic research suggests that adolescent cannabis use is associated with psychological distress (i.e. depression and anxiety symptoms); however, most studies have relied on 20th‐century data, when cannabis was significantly less potent than today.
André J. McDonald, Amanda Doggett, Susan J. Bondy, Ian Colman, Steven Cook, Hayley A. Hamilton, Paul Kurdyak, Scott T. Leatherdale, Daniel T. Myran, Jürgen Rehm, Christine M. Wickens, James MacKillop, Jillian Halladay   +12 more
wiley   +1 more source