Results 101 to 110 of about 54,731 (237)

Efficacy of omega‐3 fatty acids as a functional food: a multifaceted approach to health reinforcement

Journal of the Science of Food and Agriculture, Volume 106, Issue 8, Page 4521-4549, June 2026.
Abstract Omega‐3 fatty acids (omega‐3s) are polyunsaturated fatty acids linked with numerous health benefits. Omega‐3s exhibit multifaceted activities through various mechanisms. Eicosapentaenoic acid (EPA) alleviates oxidative stress by lowering reactive oxygen species and improving oxidative stress in brain tissues and acts against neurodegenerative ...
Md Faruque Ahmad, Abdulrahman A Alsayegh, Anjum Khanam, Awais Ahmed, António Raposo, Farkad Bantun, Md Zeyaullah, Ahmad O Babalghith, Abdullah F Aldairi, Boshra Mozaffar, Mohammed F Bajahzer, Mohamed H Abdelrahman, Mohammad Intakhab Alam   +12 more
wiley   +1 more source

Pharmacological potential of endocannabinoid and endocannabinoid-like compounds in protecting intestinal structure and metabolism under high-fat conditions

Frontiers in Pharmacology
The intestine plays a crucial role in nutrient absorption, digestion, and regulation of metabolic processes. Intestinal structure and functions are influenced by several factors, with dietary composition being one of the most significant.
Francesco Vari, Francesco Vari, Ilaria Serra, Ilaria Serra, Marzia Friuli, Viviana Cavallo, Nicola Gammaldi, Daniele Vergara, Michel Salzet, Anna M. Giudetti   +9 more
doaj   +1 more source

Endocannabinoids and epilepsy [PDF]

, 2015
The brain endocannabinoid system (ECS) plays an essential role in regulating central physiological processes that underlie learning and memory, anxiety, depression, addiction, appetite and feeding, pain, neuronal excitability and protection. A primary mode through which the ECS functions in the brain is via its regulation of synaptic transmission ...
Blair, Robert, Laxmikant Deshpande, DeLorenzo, Robert   +2 more
openaire   +1 more source

Transcriptome assemblies for two drug‐type cannabis chemotypes by long‐read RNA sequencing

The Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Cannabis sativa has undergone over 10,000 years of domestication, resulting in extensive genetic and phenotypic diversity among cultivated chemotypes. Increased medical and recreational use of specialized metabolites accumulating in cannabis glandular trichomes—primarily the cannabinoids ∆9‐tetrahydrocannabinol (THC) and cannabidiol (CBD)—has ...
Oliver Berkowitz, Ricarda Jost, Sophia Ng, Antony Bacic, James Whelan, Mathew G. Lewsey   +5 more
wiley   +1 more source

Anandamide Inhibits Vascular Smooth Muscle Migration, Endothelial Adhesion Protein Expression and Monocyte Adhesion of Human Coronary Artery Cells

Cells
Endocannabinoids have been shown to play a complex role in the pathophysiology of a number of cardiovascular disorders. In the present study, the effects of the two major endocannabinoids anandamide (AEA) and 2-arachidonoylglycerol (2-AG) were ...
Elane Blessing, Elisa Teichmann, Burkhard Hinz   +2 more
doaj   +1 more source

Endogenous Cannabinoid Production in the Rat Female Reproductive Tract Is Regulated by Changes in the Hormonal Milieu

Pharmaceuticals, 2011
The endogenous cannabinoid (eCB) system is emerging as an important component of female reproductive tract physiology. The eCBs anandamide (AEA), 2-arachidonoyl glycerol (2-AG), and N-arachidonoyl glycine (NAGly) were measured in the rat reproductive ...
Cassandra Allard, Heather B. Bradshaw
doaj   +1 more source

Metabolism of endocannabinoids

Postępy Higieny i Medycyny Doświadczalnej, 2016
Endocannabinoids belong to a group of ester, ether and amide derivatives of fatty acids, which are endogenous ligands of receptors CB1, CB2, TRPV1 and GPR55 that are included in the endocannabinoid system of the animal organism. The best known endocannabinoids are: N-arachidonylethanolamide called anandamide (AEA) and 2-arachidonoylglycerol (2-AG ...
Michał, Biernacki, Elżbieta, Skrzydlewska   +1 more
openaire   +2 more sources

Canine NAPEPLD-associated models of human myelin disorders [PDF]

, 2018
Canine leukoencephalomyelopathy (LEMP) is a juvenile-onset neurodegenerative disorder of the CNS white matter currently described in Rottweiler and Leonberger dogs. Genome-wide association study (GWAS) allowed us to map LEMP in a Leonberger cohort to dog
Bannasch, D L, Becker, D, Bellekom, S R, Cassidy, J P, Drogemuller, C, Drogemuller, M, Ekenstedt, K J, Fischer, A, Flegel, T, Furrow, E, Henke, D, Jagannathan, V, Kelly, P A, Leegwater, P A J, Letko, A, Lucot, K, Mandigers, P J J, Martineau, H, Matiasek, K, Mickelson, J R, Minor, K M, Muir, C F, Oevermann, A, Patterson, E E, Platt, S R, Priestnall, S L, Putschbach, K, Shelton, G D, Stassen, QEM   +28 more
core   +7 more sources

Modulation of the endocannabinoid system reduces inflammatory signalling in canine mammary carcinoma cells

Veterinary Record Open, Volume 13, Issue 1, June 2026.
Abstract Background Canine mammary carcinoma (CMC) is characterised by a chronic inflammatory microenvironment resembling human breast cancer; however, the upstream regulatory mechanisms driving this phenotype remain unclear. The endocannabinoid system (ECS) has emerged as a potential modulator of inflammation and tumour biology.
Gianluca Antonio Franco, Ylenia Marino, Claudia Rifici, Roberta Fusco, Davide di Paola, Salvatore Cuzzocrea, Giuseppe Catone, Cecilia Vullo, Enrico Gugliandolo   +8 more
wiley   +1 more source

Pitfalls in measuring the endocannabinoid 2-arachidonoyl glycerol in biological samples [PDF]

, 2007
Background: The endocannabinoid 2-arachidonoyl glycerol (2-AG) undergoes spontaneous isomerization to biologically inactive 1-AG. This effect has not been adequately addressed in previous studies that reported 2-AG concentrations in biological samples ...
Schelling, Gustav, Vogeser, Michael
core   +1 more source