Results 41 to 50 of about 127,657 (311)

Destination Enhancers Influencing Tourism Demand. [PDF]

African Journal of Hospitality, Tourism and Leisure, 2019
The primary objective of this article was to determine the destination enhancers that influence tourism demand. Understanding why people travel, how they go about selecting their holiday destination and why one country is preferred to the other, is vital
Prof N Oosthuizen , Dr D Ferreira
doaj  

HDAC4 in cancer: A multitasking platform to drive not only epigenetic modifications

Frontiers in Molecular Biosciences, 2023
Controlling access to genomic information and maintaining its stability are key aspects of cell life. Histone acetylation is a reversible epigenetic modification that allows access to DNA and the assembly of protein complexes that regulate mainly ...
Emma Cuttini, Camilla Goi, Ester Pellarin, Riccardo Vida, Claudio Brancolini, Claudio Brancolini   +5 more
doaj   +1 more source

daler/chromhmm-enhancers-umel: v1.0

, 2017
Identify enhancers.
Ryan Dale
core   +1 more source

Transdermal delivery of risedronate using chemical enhancers for improved skin penetration

Journal of Applied Pharmaceutical Research
Background: Risedronate sodium (RIS) is effective for bone diseases but has low bioavailability and severe side effects. This study investigates the use of hydrophilic enhancers to improve the efficiency of RIS's transdermal delivery. Methods: This study
So Hee Nam
doaj   +1 more source

Temporal analysis of enhancers during mouse cerebellar development reveals dynamic and novel regulatory functions

eLife, 2022
We have identified active enhancers in the mouse cerebellum at embryonic and postnatal stages which provides a view of novel enhancers active during cerebellar development.
Miguel Ramirez, Yuliya Badayeva, Joanna Yeung, Joshua Wu, Ayasha Abdalla-Wyse, Erin Yang, FANTOM 5 Consortium, Brett Trost, Stephen W Scherer, Daniel Goldowitz   +9 more
doaj   +1 more source

CoRE-ATAC predicted enhancers significantly overlap FANTOM and STARR-seq enhancers.

, 2021
(A) Distribution of CoRE-ATAC predictions for FANTOM enhancers in test chromosomes (chr3 and chr11). (B) Distribution of CoRE-ATAC predictions for test chromosomes.
Asa Thibodeau (3164796), Duygu Ucar (3164778), Shubham Khetan (11831776), Michael L. Stitzel (3164790), Ryan Tewhey (226068), Alper Eroglu (11368456)   +5 more
core   +1 more source

Genome-Wide Atlas of Promoter Expression Reveals Contribution of Transcribed Regulatory Elements to Genetic Control of Disuse-Mediated Atrophy of Skeletal Muscle

Biology, 2021
The prevention of muscle atrophy carries with it clinical significance for the control of increased morbidity and mortality following physical inactivity.
Sergey S. Pintus, Ilya R. Akberdin, Ivan Yevshin, Pavel Makhnovskii, Oksana Tyapkina, Islam Nigmetzyanov, Leniz Nurullin, Ruslan Devyatiyarov, Elena Shagimardanova, Daniil Popov, Fedor A. Kolpakov, Oleg Gusev, Guzel R. Gazizova   +12 more
doaj   +1 more source

Mapping the Shh long-range regulatory domain

, 2014
Coordinated gene expression controlled by long-distance enhancers is orchestrated by DNA regulatory sequences involving transcription factors and layers of control mechanisms.
Hill, Robert E, Devenney, Paul S, Lettice, Laura A, Anderson, Eve   +3 more
core   +1 more source

Shadow enhancers can suppress input transcription factor noise through distinct regulatory logic

eLife, 2020
Shadow enhancers, groups of seemingly redundant enhancers, are found in a wide range of organisms and are critical for robust developmental patterning. However, their mechanism of action is unknown.
Rachel Waymack, Alvaro Fletcher, German Enciso, Zeba Wunderlich   +3 more
doaj   +1 more source

Human Enhancement [PDF]

, 2011
Der Mensch strebt seit Urzeiten danach, seine Möglichkeiten zu erweitern und seine Leistungsfähigkeit zu steigern. Mittel dazu reichen von den ersten Werkzeugen bis zur Computertechnik, von der Erfindung des Buchdrucks bis zum drahtlosen Internet. Zunehmend beobachtbar ist die Tendenz, dass gesunde Personen Wirkstoffe zu sich nehmen in der Hoffnung auf
Eckhardt, Anne, Bachmann, Andreas, Marti, Michèle, Rütsche, Bernhard, Telser, Harry   +4 more
openaire   +4 more sources