Results 21 to 30 of about 4,495 (215)
The stress polarity signaling (SPS) pathway serves as a marker and a target in the leaky gut barrier: implications in aging and cancer. [PDF]
, 2020 The gut barrier separates trillions of microbes from the largest immune system in the body; when compromised, a "leaky" gut barrier fuels systemic inflammation, which hastens the progression of chronic diseases.
Das, Soumita +9 more
core +3 more sources
Human Sapovirus Replication in Human Intestinal Enteroids
Journal of Virology, 2023 Human sapoviruses (HuSaVs) are a frequent but overlooked cause of acute gastroenteritis, especially in children. Little is known about this pathogen, whose successful in vitro cultivation was reported only recently, in a cancer cell-derived line.
Gabriel Euller-Nicolas +8 more
openaire +4 more sources
Gastro Hep Advances, 2023 Background and Aims: A key histopathological feature of inflammatory bowel disease is damage to the mucosa, including breakdown of the epithelial barrier.
Tatiana A. Karakasheva +17 more
doaj +1 more source
Emerging Microbes and Infections, 2023 Intestinal epithelial cell interactions with enteric pathogens have been incompletely elucidated owing to the lack of model systems that recapitulate the cellular diversity, architecture and functionality of the intestine.
Miaomiao Yan +8 more
doaj +1 more source
A matter of differentiation: equine enteroids as a model for the in vivo intestinal epithelium
Veterinary ResearchEpithelial damage due to gastrointestinal disorders frequently causes severe disease in horses. To study the underlying pathophysiological processes, we aimed to establish equine jejunum and colon enteroids (eqJE, eqCE) mimicking the in vivo epithelium ...
Christina Windhaber +6 more
doaj +4 more sources
Interferon-lambda: A potent regulator of intestinal viral infections [PDF]
, 2017 Interferon-lambda (IFN-λ) is a recently described cytokine found to be of critical importance in innate immune regulation of intestinal viruses. Endogenous IFN-λ has potent antiviral effects and has been shown to control multiple intestinal viruses and ...
Baldridge, Megan T, Lee, Sanghyun
core +8 more sources
From 3D Organoids back to 2D Enteroids [PDF]
Developmental Cell, 2018 In this issue of Developmental Cell, Thorne et al. (2018) describe a simple, scalable method to culture 2D enteroid monolayers that surprisingly recapitulates many of the features of 3D organoid cultures and in vivo intestinal tissue and can be used for high-throughput microscopy-based experiments.
Jonathan, Braverman, Ömer H, Yilmaz
openaire +2 more sources
Intestinal epithelial replacement by transplantation of cultured murine and human cells into the small intestine. [PDF]
, 2019 Adult intestinal epithelial stem cells are a promising resource for treatment of intestinal epithelial disorders that cause intestinal failure and for intestinal tissue engineering.
Cho, Yonghoon +9 more
core +2 more sources
Corrigendum: Organoid and Enteroid Modeling of Salmonella Infection [PDF]
Frontiers in Cellular and Infection Microbiology, 2018 [This corrects the article DOI: 10.3389/fcimb.2018.00102.].
Yuebang Yin, Daoguo Zhou, Daoguo Zhou
openaire +3 more sources
Di-san junyi daxue xuebao, 2020 Objective To compare the potentiality and characteristics of different intestinal epithelial cell (IEC) lines to grow into enteroids when cultured in 3D system in order to provide experimental basis for the cultivation of enteroids by IECs. Methods Three
OU Jing, XU Zhenni, LIU Dengqun
doaj +1 more source