Results 81 to 90 of about 3,117 (204)
Natural Products as Potential Resource Library for Control of Major Swine Enteric Viruses
Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.Major swine enteric viruses (SEVs), including porcine epidemic diarrhea virus (PEDV), porcine deltacoronavirus (PDCoV), transmissible gastroenteritis virus (TGEV), swine acute diarrhea syndrome coronavirus (SADS‐CoV), and porcine rotavirus (PoRV), cause severe gastrointestinal diseases in pigs, leading to huge economic losses to the swine industry ...
Jialu Zhang +7 more
wiley +1 more source
The efficacy of apical-out chicken enteroids as a model for screening eubiotics
Li, YihangAntibiotic restrictions in food animal production have led to the need for alternatives to achieve comparable effects. Study of feed additives to replace antibiotics, termed eubiotics, are often studied in vivo.
Mann, Peter
core +1 more source
Image_6_Human Intestinal Enteroids Model MHC-II in the Gut Epithelium.JPEG
, 2019 The role of intestinal epithelial cells (IECs) in mucosal tolerance and immunity remains poorly understood. We present a method for inducing MHC class II (MHC-II) in human enteroids, “mini-guts” derived from small intestinal crypt stem cells, and show ...
Jonathan E. Wosen (7280258) +8 more
core +1 more source
Immune and Immune‐Integrated Organoids as NextGeneration Platforms for Disease Modeling
MedComm, Volume 6, Issue 12, December 2025.This graphical abstract outlines the sources and methods for integrating immune cells into organoids. Immune cells can be derived from peripheral blood, tissues, or differentiated from human‐induced pluripotent stem cells. The immune cells are incorporated into the organoid by using coculture techniques, direct injection, as well as scaffolds and air ...
Kimiya Rashidan +5 more
wiley +1 more source
Image_8_Human Intestinal Enteroids Model MHC-II in the Gut Epithelium.JPEG
, 2019 The role of intestinal epithelial cells (IECs) in mucosal tolerance and immunity remains poorly understood. We present a method for inducing MHC class II (MHC-II) in human enteroids, “mini-guts” derived from small intestinal crypt stem cells, and show ...
Jonathan E. Wosen (7280258) +8 more
core +1 more source
Generation of Intestinal and Colonic Organoids Derived From Human Pluripotent Stem Cells
Biology of the Cell, Volume 117, Issue 12, December 2025.Human pluripotent stem cells can be guided through a stepwise differentiation process to produce self‐organizing intestinal and colonic organoids. The resulting organoids recapitulate fetal‐stage epithelial and mesenchymal organization, offering a powerful model to explore human gastrointestinal development and its disorders.
Lola Bonneau +7 more
wiley +1 more source
, 2021 © 2020 Epithelial organoids derived from human donor tissues are important tools in fields ranging from regenerative medicine to drug discovery. Organoid culture requires expansion of stem/progenitor cells in Matrigel, a tumor-derived extracellular ...
Griffith, Linda G +9 more
core +1 more source
Reviews in Medical Virology, Volume 35, Issue 6, November 2025.ABSTRACT Common variable immunodeficiency (CVID) is the most prevalent symptomatic primary immunodeficiency, characterised by impaired antibody production, immune dysregulation, and a broad spectrum of clinical manifestations. Gastrointestinal involvement is frequent, affecting up to 20% of patients and significantly contributing to morbidity and ...
Györgyi Műzes, Ferenc Sipos
wiley +1 more source
Insights into human norovirus cultivation in human intestinal enteroids
mSphereABSTRACT Human noroviruses (HuNoVs) are a significant cause of epidemic and sporadic acute gastroenteritis worldwide. The lack of a reproducible culture system hindered the study of HuNoV replication and pathogenesis for almost a half-century.
Khalil Ettayebi +15 more
openaire +5 more sources
Ex Vivo Enteroids Recapitulate In Vivo Citrulline Production in Mice [PDF]
The Journal of Nutrition, 2018 The endogenous production of arginine relies on the synthesis of citrulline by enteral ornithine transcarbamylase (OTC). Mutations in the gene coding for this enzyme are the most frequent cause of urea cycle disorders. There is a lack of correlation between in vivo metabolic function and DNA sequence, transcript abundance, or in vitro enzyme activity ...
Xiaoying Wang +4 more
openaire +2 more sources