Results 81 to 90 of about 31,210 (261)

(-)-Epicatechin does not sensitize normal cells to radiation.

, 2014
(A) 20 µM (-)-Epicatechin does not sensitize HNF cells to radiation (REF = 0.9). (B) (-)-Epicatechin alone does not inhibit colony formation in HNF (p>0.05).
Maik Hüttemann (479906), Hosam A. Elbaz (582932), Jenney Liu (582934), Steven P. Zielske (582935), Icksoo Lee (479905), Deborah A. Antwih (582933)   +5 more
core   +1 more source

Iron Physiology and Its Impact on Atopic Diseases: An EAACI Taskforce Report

Allergy, EarlyView.
ABSTRACT Iron is essential for oxygen transport, energy metabolism, and immune regulation. Yet iron deficiency is the most common micronutrient disorder across all age groups, affecting nearly one quarter of the global population. Iron deficiency triggers nutritional immunity, a host defense mechanism that withholds and redistributes iron, contributing
Franziska Roth‐Walter, Ioana Agache, Beatriz Cabanillas, Roberto Berni Canani, Pasquale Comberiati, Holger Garn, Cristina Gomez‐Casado, Karin Hufnagl, Ekaterina Khaleva, Gregorio P. Milani, Daniel Munblit, Nikolaos Douladiris, Liam O'Mahony, Frank Redegeld, Carmen Riggioni, Peter K. Smith, Betty van Esch, Emilia Vassilopoulou, Carina Venter, Diego G. Peroni   +19 more
wiley   +1 more source

Modulation of Endoplasmic Reticulum Stress by Selected Polyphenols from Sambucus ebulus L. Fruit

Plants
When misfolded or unfolded proteins accumulate in the endoplasmic reticulum (ER), ER stress occurs, which contributes to the pathogenesis of various diseases. A previous study from our research group showed that aqueous extract from the Sambucus ebulus L.
Stoyan Stoyanov, Momchil Barbolov, Galina Yaneva, Oskan Tasinov   +3 more
doaj   +1 more source

Production of Instant Linden Tea (<i>Tilia</i> spp.) Powder: Integrating Compound-Level Infusion Kinetics With Response Surface-Optimized Spray Drying. [PDF]

Food Sci Nutr
Linden tea infusion kinetics were optimized at 80°C for 45 min to maximize flavonoid extraction. Optimal spray‐drying conditions (170°C, 10 mL/min, 10% maltodextrin) were determined using a Box‐Behnken design, yielding an instant powder with excellent solubility and preserved phenolic profile.
Altiok E, Kasapoglu C.
europepmc   +2 more sources

Unravelling polyphenol skin permeation: A comparative study using full‐thickness 3D in vitro and ex vivo human skin models

International Journal of Cosmetic Science, EarlyView.
This study demonstrates that full‐thickness 3D in vitro skin models reliably assess the permeation of cosmetic polyphenols, revealing compound‐specific transport profiles and bridging the gap between conventional cell models and ex vivo human skin, while offering an ethical and robust alternative for dermal absorption screening. Abstract The evaluation
Mariana Marques, Filipa Teixeira, Mónica Vieira, M. Helena Amaral, Paulo C. Costa, Stefano Dall'Acqua, Francisca Rodrigues   +6 more
wiley   +1 more source

Effect of (–)-epicatechin-3-gallate and (–)-epigallocatechin-3-gallate on the binding of tegafur to human serum albumin as determined by spectroscopy, isothermal titration calorimetry, and molecular docking

, 2018
Green tea has attracted great interest as a cancer prevention agent. Interactions of tea polyphenols with serum albumin may influence the efficacy of drugs.
Jun Han (231645), Liying Liu (132271), Lixia Yuan (1747378), Min Liu (45756), Yabo Shi (5957945), Hui Yan (117134)   +5 more
core   +1 more source

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

Obesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey, Irene Pomares‐Bri, Paula de Juan‐Maciá, Mariló Olivares‐Vicente, Enrique Barrajón‐Catalán, Vicente Micol, Enrique Roche, María Herranz‐López   +7 more
wiley   +1 more source

Response of Melissa officinalis subsp. officinalis seedlings to Fe3O4‐NPs under in vitro conditions: physiological, biochemical and molecular analyses

Plant Biology, EarlyView.
Iron oxide nanoparticles influence the growth, antioxidant capacity, and gene activity of Melissa officinalis subsp. officinalis plants in vitro, revealing their potential as modulators of secondary metabolism. Abstract Application of iron oxide nanoparticles (NP) (Fe3O4‐NPs) in plant biotechnology presents new opportunities for enhancing metabolic ...
E. Bektaş, H. Şahin, H. İ. Güler, K. İ. Bektaş, K. Kaltalioğlu, N. E. Uzun   +5 more
wiley   +1 more source

Epicatechin Provides Antioxidant Protection to Bovine Spermatozoa Subjected to Induced Oxidative Stress

Molecules, 2019
Epicatechin (EPI) is a natural flavonoid with antibacterial, anti-inflammatory and anti-cancer properties. Furthermore, the molecule exhibits powerful reactive oxygen species (ROS) scavenging and metal-chelating properties. In this study, we assessed the
Eva Tvrda, Peter Straka, Drahomir Galbavy, Peter Ivanic   +3 more
doaj   +1 more source

Human O-sulfated metabolites of (−)-epicatechin and methyl-(−)-epicatechin are poor substrates for commercial aryl-sulfatases: Implications for studies concerned with quantifying epicatechin bioavailability

Pharmacological Research, 2012
Epicatechin is a widely consumed dietary flavonoid and there is substantial evidence that it contributes to the health benefits reported for flavanol-rich cocoa products including dark chocolate. Numerous reports have described the appearance of epicatechin and epicatechin phase-2 conjugates (sulfates and glucuronides of epicatechin and ...
S, Saha, W, Hollands, P W, Needs, L M, Ostertag, B, de Roos, G G, Duthie, P A, Kroon   +6 more
openaire   +2 more sources