Results 71 to 80 of about 6,200 (160)

Biological aging and lifespan in men and women using a Mendelian randomization study

Human Genomics
Purpose Identification of targets of intervention to promote lifespan is crucial given lifespan is an important measure of public health. Telomere length and epigenetic clocks are key biological markers of aging, whether they are targets of intervention ...
C. M. Schooling, Shun Li, Zhu Liduzi Jiesisibieke   +2 more
doaj   +1 more source

Epigenetic clock: a promising mirror of ageing [PDF]

The Lancet Healthy Longevity, 2021
Zuyun Liu, Yimin Zhu
openaire   +3 more sources

Epigenetic signatures, age acceleration, and injury risk in elite female and male soccer players

Scientific Reports
Physical activity has been extensively associated with epigenetic modifications. However, the potential contribution of DNA methylation patterns to sports injury susceptibility remains largely unexplored, particularly among high-performance athletes ...
Raúl F. Pérez, Jon Lecumberri-Arteta, Marta Kulis, Teresa Botta-Orfila, Aina Rodríguez-Vilarrupla, Xavier Yanguas, Eva Ferrer, Gil Rodas, Jose I. Martin-Subero   +8 more
doaj   +1 more source

Association of epigenetic aging with plasma biomarkers of amyloid, tau, neurodegeneration, and neuroinflammation in Hispanic/Latino adults

Clinical Epigenetics
Background Blood-based biomarkers hold significant promise for the early detection and diagnosis of Alzheimer’s disease (AD) and other dementias. Age-related changes in blood levels of AD biomarkers are well-documented but poorly understood.
Myriam Fornage, Wassim Tarraf, Martha L. Daviglus, Charles DeCarli, Kevin A. Gonzalez, Carmen R. Isasi, Sayaka Kuwayama, Melissa Lamar, Bonnie E. Levin, Humberto Parada, Alberto R. Ramos, Tatjana Rundek, Bharat Thyagarajan, Hector M. González   +13 more
doaj   +1 more source

Distinct epigenetic aging in sporadic and hereditary neuroendocrine neoplasms

Clinical Epigenetics
Background Epigenetic clocks assess DNA aging based on DNA methylation. We aimed to study the utility of methylation clocks in understanding the distinct characteristics of sporadic and hereditary neuroendocrine neoplasms (NEN).
Shiri Weinstein, Reut Halperin, Amit Tirosh   +2 more
doaj   +1 more source

Epigenetic Regulation of Aging and its Rejuvenation

MedComm
Aging increases the global burden of disease, yet its molecular basis remains incompletely understood. Recent studies indicate that reversible epigenetic drift—spanning DNA methylation clocks, histone codes, three‐dimensional chromatin, and noncoding RNA
Yongpan An, Qian Wang, Ke Gao, Chi Zhang, Yanan Ouyang, Ruixiao Li, Zhou Ma, Tong Wu, Lifan Zhou, Zhengwei Xie, Rui Zhang, Guojun Wu   +11 more
doaj   +1 more source

Longitudinal changes in epigenetic clocks predict survival in the InCHIANTI cohort. [PDF]

Nat Aging
Kuo PL, Moore AZ, Tanaka T, Belsky DW, Lu AT, Horvath S, Bandinelli S, Ferrucci L.   +7 more
europepmc   +1 more source

From population science to the clinic? Limits of epigenetic clocks as personal biomarkers. [PDF]

Epigenomics
Apsley AT, Etzel L, Ye Q, Shalev I.
europepmc   +1 more source

Erratum: Placental epigenetic clocks derived from crowdsourcing: Implications for the study of accelerated aging in obstetrics. [PDF]

iScience
Bhatti G, Sufriyana H, Romero R, Patel T, Tekola-Ayele F, Alsaggaf I, Gomez-Lopez N, Su ECY, Done B, Hoffmann S, van Bömmel A, Wan C, Albrecht J, Novak C, DREAM Placenta Clock Challenge Consortium, Chaiworapongsa T, Sirota M, Aghaeepour N, Stolovitzky G, Bryant DR, Tarca AL.   +20 more
europepmc   +1 more source

Epigenetic clock work ticks forward

Nature Aging
C. P. Ryan, D. W. Belsky
openaire   +2 more sources