Results 41 to 50 of about 5,351 (235)

Immunity and autoantibodies of a mouse strain with autistic-like behavior

Brain, Behavior, & Immunity - Health, 2020
Female and male mice of the BTBR T+Itpr3tf/J (BTBR) strain have behaviors that resemble autism spectrum disorder. In comparison to C57BL/6 (B6) mice, BTBR mice have elevated humoral immunity, in that they have naturally high serum IgG levels and generate
Mohammad Nizam Uddin, Yunyi Yao, Tapan Mondal, Rosemary Matala, Kevin Manley, Qishan Lin, David A. Lawrence   +6 more
doaj   +1 more source

RNA Modification Related Diseases and Sensing Methods

Applied Sciences, 2023
Epitranscriptomics is the study of RNA base modifications, including functionally relevant transcriptomic changes. Epitranscriptomics has been actively studied in recent years and has been reported to play important roles in development, homeostasis, the
Mayuka Ohkawa, Masamitsu Konno
doaj   +1 more source

Functional roles of epitranscriptomic marks in the cardiovascular system and disease: a narrative review [PDF]

, 2022
BACKGROUND AND OBJECTIVE: The recent emergence of epitranscriptomics provides an avenue for identifying RNA modifications implicated in the pathophysiology of human disease.
Ilieva, Mirolyuba Simeonova, Uchida, Shizuka   +1 more
core   +1 more source

The role of post-transcriptional regulation in SARS-CoV-2 infection and pathogenicity

Frontiers in Immunology, 2023
The COVID-19 pandemic caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) virus has had a significant impact on global social and economic stability.
Xuan Wang, Zecheng Chang, Tingting Zhao, Weiyao Zhong, Jingwei Shi, Guoqing Wang, Xuesong Xu   +6 more
doaj   +1 more source

Translating the epitranscriptome [PDF]

WIREs RNA, 2016
RNAmodifications are indispensable for the translation machinery to provide accurate and efficient protein synthesis. Whereas the importance of transfer RNA (tRNA) and ribosomal RNA (rRNA) modifications has been well described and is unquestioned for decades, the significance of internal messenger RNA (mRNA) modifications has only recently been ...
Hoernes, Thomas Philipp, Erlacher, Matthias David   +1 more
openaire   +2 more sources

[Epitranscriptomics].

Medecine sciences : M/S
Anna Salvetti
semanticscholar   +3 more sources

Epitranscriptomics of Ischemic Heart Disease—The IHD-EPITRAN Study Design and Objectives [PDF]

, 2021
Epitranscriptomic modifications in RNA can dramatically alter the way our genetic code is deciphered. Cells utilize these modifications not only to maintain physiological processes, but also to respond to extracellular cues and various stressors.
Biancari, Fausto, Blokhina, Daria, Bäckström, Pia, Dahlbacka, Sebastian, Elomaa, Outi, Eskin, Arda, Jormalainen, Mikko, Juvonen, Tatu, Kaarne, Markku, Kankuri, Esko, Karelson, Mati, Karjalainen, Pasi, Katayama, Shintaro, Khan, Jahangir, Kiss, Jan, Koivisto, Pertti, Laine, Mika, Lalowski, Maciej, Laurikka, Jari, Lemström, Karl, Mervaala, Eero, Nummi, Annu, Nykänen, Antti, Oksaharju, Kati, Raivio, Peter, Rajala, Helena, Ropponen, Jussi, Savinainen, Kimmo, Sikorski, Vilbert, Simpanen, Jarmo, Stark, Christoffer, Suihko, Satu, Syrjälä, Simo, Teittinen, Kari, Tuncbag, Nurcan, Tuohinen, Suvi, Vainikka, Tiina, Vento, Antti, Vähäsilta, Tommi   +38 more
core   +6 more sources

Holistic Optimization of Bioinformatic Analysis Pipeline for Detection and Quantification of 2′-O-Methylations in RNA by RiboMethSeq

Frontiers in Genetics, 2020
A major trend in the epitranscriptomics field over the last 5 years has been the high-throughput analysis of RNA modifications by a combination of specific chemical treatment(s), followed by library preparation and deep sequencing.
Florian Pichot, Florian Pichot, Florian Pichot, Virginie Marchand, Lilia Ayadi, Lilia Ayadi, Valérie Bourguignon-Igel, Valérie Bourguignon-Igel, Mark Helm, Yuri Motorin, Yuri Motorin   +10 more
doaj   +1 more source

Positioning Europe for the EPITRANSCRIPTOMICS challenge [PDF]

, 2018
The genetic alphabet consists of the four letters: C, A, G, and T in DNA and C,A,G, and U in RNA. Triplets of these four letters jointly encode 20 different amino acids out of which proteins of all organisms are built.
Almeida, Raquel, Ameres, Stefan, Ayers, Duncan, Balatsos, Nikolaos, Ballana, Ester, Bankovic, Jasna, Banovic, Bojana, Baranov, Pavel, Bousquet-Antonelli, Cecile, Bujnicki, Janusz, Cardona, Fernando, Carre, Clement, Costache, Marieta, Cowling, Victoria, Dahl, John Arne, Davalos, Alberto, David, Alexandre, Demircan, Turan, Dinnyes, Andras, Drablos, Finn, Fray, Rupert, Frye, Michaela, Fuks, Francois, Helm, Mark, Holodnuka Kholodnyuk, Irina, Jantsch, Michael, Jeronimo, Carmen, Kelly, Vincent, Klungland, Arne, Kyselovic, Jan, Lafontaine, Denis, Lamm, Ayelet, Liepins, Janis, Lyko, Frank, Macias-Gonzales, Manuel, Motorin, Yuri, Neagu, Monica, Nielsen, Henrik, O Carroll, Donal, O'Connell, Mary, Ohman, Marie, Oulas, Anastasis, Pelizzola, Mattia, Pir, Pinar, Purta, Elzbieta, Quattrone, Alessandro, Rechavi, Gideon, Roignant, Jean-Yves, Rossmanith, Walter, Schaffrath, Raffael, Schwartz, Schraga, Schäfer, Matthias, Selbert, Stefan, Timotijevic, Gordana, Ule, Jernej, Valor, Luis Miguel, Vanacova, Stepanka, Verdel, Andre, Willems, Luc, Zammit, Vanessa   +59 more
core   +13 more sources

Epitranscriptome changes triggered by ammonium nutrition regulate the proteome response of maritime pine roots. [PDF]

, 2022
Epitranscriptome constitutes a gene expression checkpoint in all living organisms. Nitrogen is an essential element for plant growth and development that influences gene expression at different levels such as epigenome, transcriptome, proteome, and ...
Cañas-Pendón, Rafael Antonio, Cánovas-Ramos, Francisco Miguel, Lobato-Fernández, César, Ortigosa Peña, Francisco, Pérez-Claros, Juan Antonio, Ruiz-Canton, Francisco Javier, Ávila-Sáez, Concepción   +6 more
core   +1 more source