Results 61 to 70 of about 2,680 (197)

Frontiers in the Management of Orthopaedic Periprosthetic Joint Infection

Journal of Orthopaedic Research, Volume 44, Issue 2, February 2026.
ABSTRACT Periprosthetic joint infection (PJI) is a devastating complication of total joint arthroplasty (TJA), one of the most frequently performed surgical procedures worldwide. Management of acute PJI commonly involves debridement, antibiotics, and implant retention (DAIR), though failure rates remain high due to antibiotic‐tolerant biofilms. Chronic
Michael F. Shannon, Victoria R. Wong, Samuelson E. Osifo, Timothy Edwards, Himanshu Rao, Jewelia Rempuszewski, Andrew J. Frear, Shaan Sadhwani, Neel B. Shah, Kenneth L. Urish   +9 more
wiley   +1 more source

Antimicrobial activity of eravacycline and other comparative agents on aerobic and anaerobic bacterial pathogens in Taiwan: A clinical microbiological study

Journal of Global Antimicrobial Resistance
Objectives: Eravacycline, a new tetracycline derivative, exhibits broad-spectrum antimicrobial susceptibility. This study aimed to comprehensively investigate in vitro activities of eravacycline, tigecycline, and ertapenem against various Gram-positive ...
Ming-Han Tsai, Chyi-Liang Chen, Hsin-Ju Chang, Tzu-Chun Chuang, Cheng-Hsun Chiu   +4 more
doaj   +1 more source

A New Strategy for Persister Control [PDF]

, 2023
Eradicating persistent bacterial infections is an ever-growing problem in the medical field. Conventional antibiotics are becoming less effective against persistent infections in tuberculosis, cystic fibrosis, Lyme disease, device-associated, urinary ...
Roy, Sweta
core   +1 more source

Antimicrobial treatment challenges in the era of carbapenem resistance [PDF]

, 2019
Infections due to carbapenem-resistant Gram-negative bacteria are burdened by high mortality and represent an urgent threat to address. Clinicians are currently at a dawn of a new era in which antibiotic resistance in Gram-negative bacilli is being dealt
Doi, Yohei, Harris, Patrick N.A., Paterson, David L., Peri, Anna Maria, Potoski, Brian A., Righi, Elda   +5 more
core   +1 more source

Acinetobacter baumannii as a Model for the Study and Application of Gram‐Negative Outer Membrane Vesicles: A Systematic Review

Microbial Biotechnology, Volume 18, Issue 9, September 2025.
Investigation of outer membrane vesicles from Acinetobacter baumannii for potential biotechnological applications. ABSTRACT Outer membrane vesicles (OMVs) are extracellular nanostructures released from Gram‐negative bacteria. Acinetobacter baumannii OMVs (AbOMVs) have been extensively studied and can thus be used as a model for understanding multiple ...
Beatriz Cano‐Castaño, Mireia López‐Siles, Francesca Nonnoi, Astrid Pérez, Andrés Corral Lugo, Michael J. McConnell   +5 more
wiley   +1 more source

In vitro activities of Eravacycline against 336 isolates collected from 2012 to 2016 from 11 teaching hospitals in China

BMC Infectious Diseases, 2019
Background In China multidrug-resistant bacteria pose a considerable threat to public health. Antimicrobial resistance has weakened the effectiveness of many medicines widely used today.
Chunjiang Zhao, Xiaojuan Wang, Yawei Zhang, Ruobing Wang, Qi Wang, Henan Li, Hui Wang   +6 more
doaj   +1 more source

Drug Regimens of Novel Antibiotics in Critically Ill Patients with Varying Renal Functions: A Rapid Review

Antibiotics, 2022
There is currently an increase in the emergence of multidrug-resistant bacteria (MDR) worldwide, requiring the development of novel antibiotics. However, it is not only the choice of antibiotic that is important in treating an infection; the drug regimen
Julie Gorham, Fabio Silvio Taccone, Maya Hites   +2 more
doaj   +1 more source

A review of antibiotic safety in pregnancy—2025 update

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 45, Issue 4, Page 227-237, April 2025.
Abstract Antibiotics constitute the majority of prescriptions for women during pregnancy. Common bacterial infections, including urinary tract infections, skin and soft tissue infections, and upper and lower respiratory tract infections, are expected in pregnancy, similar to the general public.
Johny Nguyen, Victoria Madonia, Christopher M. Bland, Kayla R. Stover, Lea S. Eiland, Julia Keating, Madeline Lemmon, P. Brandon Bookstaver, as part of the Southeastern Research Group Endeavor (SERGE‐45) research network   +8 more
wiley   +1 more source

Nuevos compuestos derivados del 3-amino- 1,2-propanodiol con actividad contra Acinetobacter baumannii resistente a Colistina. Diseño, síntesis y evaluación in Vitro [PDF]

, 2016
Acinetobacter baumannii es una bacteria perteneciente al género Acinetobacter, que comprende cocobacilos Gram-negativos, aerobios estrictos, no fermentadores, catalasa positivos, oxidasa positivos e inmóviles. Es la especie más representativa, debido a
Molina Ríos, Gracia
core  

Activity and resistance mechanisms of the third generation tetracyclines tigecycline, eravacycline and omadacycline against nationwide Spanish collections of carbapenemase-producing Enterobacterales and Acinetobacter baumannii [PDF]

Multicenter study[Abstract] Introduction: The rise in multidrug-resistant bacteria challenges clinical microbiology. Tigecycline, eravacycline, and omadacycline show promise against carbapenem-resistant Enterobacterales and Acinetobacter baumannii ...
Alonso-García, Isaac, Arca-Suárez, Jorge, Beceiro, Alejandro, Blanco-Martín, Tania, Bou, Germán, Fernández-López, María del Carmen, García, Patricia, García-Pose, Andrea, González-Pinto, Lucía, Guijarro-Sánchez, Paula, Lasarte-Monterrubio, Cristina, Maceiras, Romina, Muras, Andrea, Outeda-García, Michelle, Rodríguez-Coello, Arianna, Vázquez-Ucha, Juan Carlos   +15 more
core   +1 more source