Results 61 to 70 of about 25,445 (232)
A Selective Irreversible Inhibitor of Furin Does Not Prevent Pseudomonas Aeruginosa Exotoxin A-Induced Airway Epithelial Cytotoxicity [PDF]
, 2016 Many bacterial and viral pathogens (or their toxins), including Pseudomonas aeruginosa exotoxin A, require processing by host pro-protein convertases such as furin to cause disease.
Ferguson, Timothy E. G. +4 more
core +2 more sources
Bacteriophage involvement in group A streptococcal pyrogenic exotoxin A production [PDF]
Journal of Bacteriology, 1986 Lysogenic conversion has been suggested as a mechanism of control of group A streptococcal pyrogenic exotoxin type A production. Digestion of DNA from two converting bacteriophages, 3GL16 and T12, with a variety of restriction endonucleases yielded identical DNA fragments upon electrophoresis in agarose gels. Several known A toxin-positive strains that
L P, Johnson +2 more
openaire +2 more sources
Tropical Medicine &International Health, Volume 31, Issue 3, Page 295-306, March 2026.ABSTRACT Objectives The primary objectives of this study are to (1) summarise the current landscape of ETEC vaccine development by describing, characterising and comparing ETEC vaccine candidates in clinical development, (2) assess key characteristics of the phases 1, 2 and 3 clinical trials that have been designed to evaluate ETEC vaccines in ...
Vaidehi Nafade +4 more
wiley +1 more source
Toxins, 2017 Pseudomonas aeruginosa exotoxin A (PEA) causes severe hepatotoxicity in experimental animals and is useful in investigations of immune-mediated liver injury.
Chien-Chao Chiu +7 more
doaj +1 more source
Aspergillus fumigatus enhances elastase production in pseudomonas aeruginosaco-cultures [PDF]
, 2015 In the cystic fibrosis (CF) lung the presence of bacteria and fungi in the airways promotes an inflammatory response causing progressive lung damage, ultimately leading to high rates of morbidity and mortality.
Kerr, Stephen +6 more
core +1 more source
Pseudomonas aeruginosa exotoxin A-induced hepatotoxicity in dynamics: an animal model in white mice [PDF]
Саратовский научно-медицинский журнал, 2015 Purpose: to study biochemical indices of peripheral blood which show organs functional changes. Material and Methods. The experiments were carried out on white mice in dynamics development of pseudomonas aeruginosa caused by intraperitoneal injection of ...
Morrison A.V. +2 more
doaj
Exploring the genetics of irritable bowel syndrome: A GWA study in the general population and replication in multinational case-control cohorts [PDF]
, 2014 OBJECTIVE: IBS shows genetic predisposition, but adequately powered gene-hunting efforts have been scarce so far. We sought to identify true IBS genetic risk factors by means of genome-wide association (GWA) and independent replication studies.
Agreus, Lars +43 more
core +1 more source
The future of antiviral immunotoxins [PDF]
, 2016 There is a constant need for new therapeutic interventions in a wide range of infectious diseases. Over the past few years, the immunotoxins have entered the stage as promising antiviral treatments.
Høy Jakobsen, Mette +3 more
core +1 more source
Advanced Healthcare Materials, Volume 15, Issue 7, 16 February 2026.As implantable medical devices become indispensable to modern medicine, a silent threat grows alongside them: device‐associated infections. Despite decades of antibiotic innovation, infection rates keep climbing, costing lives and billions in healthcare expenses.
Benito Baldauf +5 more
wiley +1 more source
Novel Chemokine-Based Immunotoxins for Potent and Selective Targeting of Cytomegalovirus Infected Cells [PDF]
, 2017 Immunotoxins as antiviral therapeutics are largely unexplored but have promising prospective due to their high selectivity potential and their unparalleled efficiency.
Jeppesen, Mads G. +5 more
core +5 more sources