Results 21 to 30 of about 2,205,533 (300)
Factor H-related protein 1 promotes complement-mediated opsonization of Pseudomonas aeruginosa
Frontiers in Cellular and Infection MicrobiologyPseudomonas aeruginosa is an important human opportunistic pathogen responsible for a wide range of infections. The complement system is the main early host defense mechanism to control these infections. P.
Alex González-Alsina +7 more
doaj +4 more sources
C3 Glomerulonephritis associated with Anti-complement Factor H Autoantibodies in an Adolescent Male: A Case Report [PDF]
Childhood Kidney Diseases, 2021 C3 glomerulonephritis (C3GN), a rare condition associated with dysregulation of the alternative pathway of the complement system, is histopathologically characterized by isolated or dominant C3 deposition in the renal glomeruli.
HyeSun Hyun +4 more
doaj +1 more source
Dimerization of complement factor H-related proteins modulates complement activation in vivo. [PDF]
Proc Natl Acad Sci U S A, 2013 The complement system is a key component regulation influences susceptibility to age-related macular degeneration, meningitis, and kidney disease. Variation includes genomic rearrangements within the complement factor H-related ( CFHR ) locus. Elucidating the mechanism underlying these associations has been hindered
Goicoechea de Jorge E +10 more
europepmc +6 more sources
Defining the Glycosaminoglycan Interactions of Complement Factor H–Related Protein 5 [PDF]
The Journal of Immunology, 2021 Abstract Complement activation is an important mediator of kidney injury in glomerulonephritis. Complement factor H (FH) and FH-related protein 5 (FHR-5) influence complement activation in C3 glomerulopathy and IgA nephropathy by differentially regulating glomerular complement.
Frederick Gyapon-Quast +8 more
openaire +5 more sources
Levels of soluble complement regulators predict severity of COVID-19 symptoms
Frontiers in Immunology, 2022 The SARS-CoV-2 virus continues to cause significant morbidity and mortality worldwide from COVID-19. One of the major challenges of patient management is the broad range of symptoms observed.
Anna L. Tierney +182 more
doaj +1 more source
A Family Affair: Addressing the Challenges of Factor H and the Related Proteins
Frontiers in Immunology, 2021 Inflammation is a common denominator of diseases. The complement system, an intrinsic part of the innate immune system, is a key driver of inflammation in numerous disorders.
Felix Poppelaars +11 more
doaj +1 more source
Nefrología (English Edition), 2022 The complement system is a first line of defence against infectious, tumoral or autoimmune processes, and it is constitutively regulated to avoid excessive or unspecific activation. Factor H (FH), a most relevant complement regulator, controls complement
Irene Gómez Delgado +1 more
doaj +1 more source
The pathogen Moniliophthora perniciosa promotes differential proteomic modulation of cacao genotypes with contrasting resistance to witches´ broom disease [PDF]
, 2020 Background: Witches' broom disease (WBD) of cacao (Theobroma cacao L.), caused by Moniliophthora perniciosa, is the most important limiting factor for the cacao production in Brazil.
Correa, Stephany Cristiane +4 more
core +1 more source
Nefrología, 2022 Resumen: El sistema del Complemento protege al organismo frente a procesos infecciosos, tumorales y autoinmunes, y requiere una regulación muy estricta para evitar una activación excesiva o inespecífica.
Irene Gómez Delgado +1 more
doaj +1 more source
Biomedicines, 2022 Cardiovascular disease (CVD) is the main cause of mortality among chronic kidney disease (CKD) patients, both in adults and in children. Hypertension is one of the risk factors of CVD.
Wei-Ting Liao +3 more
doaj +1 more source