Galantamine ameliorates hyperoxia-induced brain injury in neonatal mice
Frontiers in Neuroscience, 2023 Introduction:Prolonged oxygen therapy in preterm infants often leads to cognitive impairment. Hyperoxia leads to excess free radical production with subsequent neuroinflammation, astrogliosis, microgliosis and apoptosis. We hypothesized that Galantamine,
Nahla Zaghloul +5 more
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Galantamine protects against synaptic, axonal, and vision deficits in experimental neurotrauma
Neurobiology of Disease, 2020 Our goal was to investigate the neuroprotective effects of galantamine in a mouse model of blast-induced indirect traumatic optic neuropathy (bITON). Galantamine is an FDA-approved acetylcholinesterase inhibitor used to treat mild-moderate Alzheimer's ...
Sarah Naguib +4 more
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Metabolites, 2021 Alkaloids produced by the bulbs of the Amaryllidaceae are a source of pharmaceutical compounds. The main alkaloid, galantamine, is a reversible acetylcholinesterase inhibitor and allosteric nicotinic receptor modulator, which slows cognitive and ...
Dana Atrahimovich +4 more
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Beyond Cholinesterase Inhibition. Anti-Inflammatory Role and Pharmacological Profile of Current Drug Therapy for Alzheimer's Disease [PDF]
, 2016 Inflammation is a common response of an individual against either exogenous or endogenous damage. The role of inflammation and of inflammatory cells recently emerged also in the pathogenesis of neurodegenerative disorders. Experimental evidences show how
GIUBILEI, Franco
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Comparative study of the vibrational optical activity techniques in structure elucidation : the case of galantamine [PDF]
, 2019 The absolute configuration of the alkaloid galantamine was studied using a range of solution-state techniques; nuclear magnetic resonance (NMR), vibrational circular dichroism (VCD), and Raman optical activity (ROA). While the combined use of NMR and VCD
Bultinck, Patrick +4 more
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REM sleep in acutely traumatized individuals and interventions for the secondary prevention of post-traumatic stress disorder [PDF]
, 2020 Increasing evidence supports a close link between REM sleep and the consolidation of emotionally toned memories such as traumatic experiences. In order to investigate the role of sleep for the development of symptoms related to traumatic experiences ...
Bublitz, Jan Christoph +6 more
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Journal of Neuroinflammation, 2021 Background Binge ethanol exposure during adolescence reduces hippocampal neurogenesis, a reduction which persists throughout adulthood despite abstinence.
Victoria Macht +3 more
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Early and Differential Diagnosis of Dementia and Mild Cognitive Impairment Design and Cohort Baseline Characteristics of the German Dementia Competence Network [PDF]
, 2009 Background: The German Dementia Competence Network (DCN) has established procedures for standardized multicenter acquisition of clinical, biological and imaging data, for centralized data management, and for the evaluation of new treatments.
Frölich, Lutz +21 more
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Mortality and Malnutrition Among Populations Living in South Darfur, Sudan: Results of 3 Surveys, September 2004. [PDF]
, 2005 CONTEXT: Mass violence against civilians in the west of Sudan has resulted in the displacement of more than 1.5 million people (25% of the population of the Darfur region). Most of these people are camped in 142 settlements.
Brown, V +4 more
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Nootropics use in the workplace. Psychiatric and ethical aftermath towards the new frontier of bioengineering [PDF]
, 2020 OBJECTIVE: The authors have sought to expound upon and shed a light on the rise of nootropics, which have gradually taken on a more and more relevant role in workplaces and academic settings.
Bersani, G +5 more
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