International Journal of Molecular Sciences, 2022 Oxidative stress is an essential factor in the development and progression of Alzheimer’s disease (AD). An excessive amount of reactive oxygen species (ROS) induces the peroxidation of lipid membranes, reduces the activity of antioxidant enzymes and ...
Rumyana Simeonova +4 more
semanticscholar +1 more source
Beyond Cholinesterase Inhibition. Anti-Inflammatory Role and Pharmacological Profile of Current Drug Therapy for Alzheimer's Disease [PDF]
, 2016 Inflammation is a common response of an individual against either exogenous or endogenous damage. The role of inflammation and of inflammatory cells recently emerged also in the pathogenesis of neurodegenerative disorders. Experimental evidences show how
GIUBILEI, Franco
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International Journal of Molecular Sciences, 2022 The Michaelis–Menten model of enzyme kinetic assumes the free ligand approximation, the steady-state approximation and the rapid equilibrium approximation.
D. Lamba, A. Pesaresi
semanticscholar +1 more source
Early and Differential Diagnosis of Dementia and Mild Cognitive Impairment Design and Cohort Baseline Characteristics of the German Dementia Competence Network [PDF]
, 2009 Background: The German Dementia Competence Network (DCN) has established procedures for standardized multicenter acquisition of clinical, biological and imaging data, for centralized data management, and for the evaluation of new treatments.
Frölich, Lutz +21 more
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REM sleep in acutely traumatized individuals and interventions for the secondary prevention of post-traumatic stress disorder [PDF]
, 2020 Increasing evidence supports a close link between REM sleep and the consolidation of emotionally toned memories such as traumatic experiences. In order to investigate the role of sleep for the development of symptoms related to traumatic experiences ...
Bublitz, Jan Christoph +6 more
core +1 more source
Frontiers in Behavioral Neuroscience, 2021 Binge drinking and alcohol abuse are common during adolescence and cause both cognitive deficits and lasting cholinergic pathology in the adult basal forebrain.
F. Crews +3 more
semanticscholar +1 more source
Comparative study of the vibrational optical activity techniques in structure elucidation : the case of galantamine [PDF]
, 2019 The absolute configuration of the alkaloid galantamine was studied using a range of solution-state techniques; nuclear magnetic resonance (NMR), vibrational circular dichroism (VCD), and Raman optical activity (ROA). While the combined use of NMR and VCD
Bultinck, Patrick +4 more
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Nootropics use in the workplace. Psychiatric and ethical aftermath towards the new frontier of bioengineering [PDF]
, 2020 OBJECTIVE: The authors have sought to expound upon and shed a light on the rise of nootropics, which have gradually taken on a more and more relevant role in workplaces and academic settings.
Bersani, G +5 more
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Journal of Drug Delivery and Therapeutics, 2022 Galantamine, like nor-belladine, is a benzazepine. Galanthus and other plants of the Amaryllidaceae are the most common sources of it. Galantamine is used to combat the muscle effects of gallamine triethiodide and tubocurarine by acting as a ...
Jaspreet Kaur +4 more
semanticscholar +1 more source
Mortality and Malnutrition Among Populations Living in South Darfur, Sudan: Results of 3 Surveys, September 2004. [PDF]
, 2005 CONTEXT: Mass violence against civilians in the west of Sudan has resulted in the displacement of more than 1.5 million people (25% of the population of the Darfur region). Most of these people are camped in 142 settlements.
Brown, V +4 more
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