Results 51 to 60 of about 23,209 (275)

Potential therapeutic use of the ketogenic diet in autism spectrum disorders. [PDF]

open access: yes, 2014
The ketogenic diet (KGD) has been recognized as an effective treatment for individuals with glucose transporter 1 (GLUT1) and pyruvate dehydrogenase (PDH) deficiencies as well as with epilepsy.
Dueñas, Nadia   +2 more
core   +1 more source

Het effect van galantamine op de ecg- geleidingstijden

open access: yesTijdschrift voor Gerontologie en Geriatrie, 2014
Achtergrond Galantamine, een acethylcholinesterase-remmer (AChE-remmer), is geregistreerd voor de symptomatische behandeling van lichte tot matig ernstige dementie van het Alzheimer-type.
I. C. Jobse, R. A. M. de Jonckheere
doaj   +1 more source

Effects of 3R, 16S-2-hydroxyethyl apovincaminate (HEAPO), donepezil and galantamine on learning and memory retention in naïve Wistar rats

open access: yesActa Pharmaceutica, 2023
The effects of 3R,16S-2-hydroxyethyl apovincaminate (HEAPO, RGH-10885) compared with those of two cholinesterase inhibitors, donepezil and galantamine, were examined in naïve Wistar rats using standard active and passive avoidance tests.
Dimitrova Darinka   +2 more
doaj   +1 more source

Inhibition of Connexin43 hemichannels impairs spatial short-term memory without affecting spatial working memory [PDF]

open access: yes, 2016
Astrocytes are active players in higher brain function as they can release gliotransmitters, which are essential for synaptic plasticity. Various mechanisms have been proposed for gliotransmission, including vesicular mechanisms as well as non-vesicular ...
Albertini, Giulia   +5 more
core   +2 more sources

Antidiabetic Effect of Galantamine: Novel Effect for a Known Centrally Acting Drug.

open access: yesPLoS ONE, 2015
The cholinergic anti-inflammatory pathway is one of the putative biochemical pathways that link diabetes with Alzheimer disease. Hence, we aimed to verify the potential antidiabetic effect of galantamine, unveil the possible mechanisms and evaluate its ...
Mennatallah A Ali   +3 more
doaj   +1 more source

Determination of galantamine in human plasma by LC-MS/MS using carbamazepine as an internal standard: Method validation and application to a pharmacokinetic study of galantamine hydrobromide prolonged-release capsules in healthy Thai volunteers

open access: yesCogent Medicine, 2020
A rapid, sensitive and reliable LC-MS/MS method for the determination of galantamine in plasma was developed and validated for the pharmacokinetic study of galantamine hydrobromide 8 mg prolonged-release capsules. The plasma sample was prepared by simple
Darunee Hongwiset   +4 more
doaj   +1 more source

Catecholamine-Based Treatment in AD Patients: Expectations and Delusions. [PDF]

open access: yes, 2015
In Alzheimer disease, the gap between excellence of diagnostics and efficacy of therapy is wide. Despite sophisticated imaging and biochemical markers, the efficacy of available therapeutic options is limited.
Alessandro eStefani   +9 more
core   +3 more sources

Acute response to cholinergic challenge predicts long‐term response to galantamine treatment in patients with Alzheimer's disease

open access: yesBritish Journal of Clinical Pharmacology, 2021
Cholinesterase inhibitors (CEIs) have been shown to improve cognitive functioning in Alzheimer's disease (AD) patients, but are associated with multiple side effects and only 20–40% of the patients clinically improve.
Anne C Baakman   +14 more
semanticscholar   +1 more source

Alzheimer’s disease: clinical management errors

open access: yesМедицинский совет, 2020
The management of patients with Alzheimer’s disease (AD) is one of the urgent problems of modern medicine, however, not only general practitioners, but also neurologists in our country are not sufficiently aware of modern methods of AD therapy, which ...
V. A. Parfenov
doaj   +1 more source

The spleen: a hub connecting nervous and immune systems in cardiovascular and metabolic diseases [PDF]

open access: yes, 2017
Metabolic disorders have been identified as major health problems affecting a large portion of the world population. In addition, obesity and insulin resistance are principal risk factors for the development of cardiovascular diseases.
Carnevale, Daniela   +3 more
core   +2 more sources

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