Results 51 to 60 of about 23,209 (275)
Potential therapeutic use of the ketogenic diet in autism spectrum disorders. [PDF]
The ketogenic diet (KGD) has been recognized as an effective treatment for individuals with glucose transporter 1 (GLUT1) and pyruvate dehydrogenase (PDH) deficiencies as well as with epilepsy.
Dueñas, Nadia +2 more
core +1 more source
Het effect van galantamine op de ecg- geleidingstijden
Achtergrond Galantamine, een acethylcholinesterase-remmer (AChE-remmer), is geregistreerd voor de symptomatische behandeling van lichte tot matig ernstige dementie van het Alzheimer-type.
I. C. Jobse, R. A. M. de Jonckheere
doaj +1 more source
The effects of 3R,16S-2-hydroxyethyl apovincaminate (HEAPO, RGH-10885) compared with those of two cholinesterase inhibitors, donepezil and galantamine, were examined in naïve Wistar rats using standard active and passive avoidance tests.
Dimitrova Darinka +2 more
doaj +1 more source
Inhibition of Connexin43 hemichannels impairs spatial short-term memory without affecting spatial working memory [PDF]
Astrocytes are active players in higher brain function as they can release gliotransmitters, which are essential for synaptic plasticity. Various mechanisms have been proposed for gliotransmission, including vesicular mechanisms as well as non-vesicular ...
Albertini, Giulia +5 more
core +2 more sources
Antidiabetic Effect of Galantamine: Novel Effect for a Known Centrally Acting Drug.
The cholinergic anti-inflammatory pathway is one of the putative biochemical pathways that link diabetes with Alzheimer disease. Hence, we aimed to verify the potential antidiabetic effect of galantamine, unveil the possible mechanisms and evaluate its ...
Mennatallah A Ali +3 more
doaj +1 more source
A rapid, sensitive and reliable LC-MS/MS method for the determination of galantamine in plasma was developed and validated for the pharmacokinetic study of galantamine hydrobromide 8 mg prolonged-release capsules. The plasma sample was prepared by simple
Darunee Hongwiset +4 more
doaj +1 more source
Catecholamine-Based Treatment in AD Patients: Expectations and Delusions. [PDF]
In Alzheimer disease, the gap between excellence of diagnostics and efficacy of therapy is wide. Despite sophisticated imaging and biochemical markers, the efficacy of available therapeutic options is limited.
Alessandro eStefani +9 more
core +3 more sources
Cholinesterase inhibitors (CEIs) have been shown to improve cognitive functioning in Alzheimer's disease (AD) patients, but are associated with multiple side effects and only 20–40% of the patients clinically improve.
Anne C Baakman +14 more
semanticscholar +1 more source
Alzheimer’s disease: clinical management errors
The management of patients with Alzheimer’s disease (AD) is one of the urgent problems of modern medicine, however, not only general practitioners, but also neurologists in our country are not sufficiently aware of modern methods of AD therapy, which ...
V. A. Parfenov
doaj +1 more source
The spleen: a hub connecting nervous and immune systems in cardiovascular and metabolic diseases [PDF]
Metabolic disorders have been identified as major health problems affecting a large portion of the world population. In addition, obesity and insulin resistance are principal risk factors for the development of cardiovascular diseases.
Carnevale, Daniela +3 more
core +2 more sources

