Results 61 to 70 of about 23,209 (275)

Meta-Analysis of Randomized Controlled Trials on the Efficacy and Safety of Donepezil, Galantamine, Rivastigmine, and Memantine for the Treatment of Alzheimer’s Disease

Frontiers in Neuroscience, 2019
To study the impact of donepezil, rivastigmine, galantamine, and memantine on cognitive, functional, behavioral, global changes and adverse effects in patients with mild, moderate and severe Alzheimer’s disease (AD), we screened the literature published ...
Dandan Li, Ya-hong Zhang, Wei Zhang, Pu Zhao   +3 more
semanticscholar   +1 more source

Recent advances in the total synthesis of galantamine, a natural medicine for Alzheimer's disease.

Natural product reports (Print)
Covering: 2006 to 2023(-)-Galantamine is a natural product with distinctive structural features and potent inhibitory activity against acetylcholine esterase (AChE). It is clinically approved for the treatment of Alzheimer's disease.
Bichu Cheng, Qi Wang, Yi An, Fen‐er Chen   +3 more
semanticscholar   +1 more source

Anti-Cholinesterase Combination Drug Therapy as a Potential Treatment for Alzheimer’s Disease

Brain Sciences, 2021
Alzheimer’s disease (AD) is a burgeoning social and healthcare problem. Cholinesterase inhibitors (ChEIs) are employed for symptomatic treatment of AD, but often elicit adverse drug reactions (ADRs).
Hafsa Amat-ur-Rasool, Mehboob Ahmed, Shahida Hasnain, Wayne G. Carter   +3 more
doaj   +1 more source

The influence of in vitro gastrointestinal digestion on the chemical composition and antioxidant and enzyme inhibitory capacities of carob liqueurs obtained with different elaboration techniques [PDF]

, 2019
Carob liqueur is a traditional Mediterranean alcoholic beverage obtained via a wide range of production techniques contributing to the different organoleptic attributes of the final product.
Coelho, Natacha, Gonçalves, Sandra, Pérez-Santín, Efrén, Rodríguez Solana, Raquel, Romano, Anabela, Santos-Rufo, Antonio   +5 more
core   +1 more source

Effect of photoperiod and plant growth regulators on in vitro mass bulblet proliferation of Narcissus tazzeta L. (Amaryllidaceae), a potential source of galantamine

Plant Cell Tissue and Organ Culture, 2020
Narcissus tazetta L., a bulbous plant belongs to the Amaryllidaceae family, contains alkaloid galantamine (GAL) with acetylcholinesterase inhibitory activity which has been recently considered to treat Alzheimer’s disease (AD).
Majid Rahimi Khonakdari, H. Rezadoost, R. Heydari, M. Mirjalili   +3 more
semanticscholar   +1 more source

Structural MRI of the basal forebrain as predictor of cognitive response to galantamine in healthy older adults—A randomized controlled double‐blinded crossover study

Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2021
Introduction Cholinesterase inhibitors can enhance cognitive functions in healthy elderly and delay cognitive decline in patients with Alzheimer`s disease (AD). However, not everyone benefits from this treatment (non‐responders).
Patrick Müller, Anne‐Katrin Vellage, Marlen Schmicker, Inga Menze, Michel J. Grothe, Stefan J. Teipel, Notger G. Müller   +6 more
doaj   +1 more source

The kynurenine pathway and the brain: challenges, controversies and promises [PDF]

, 2017
Research on the neurobiology of the kynurenine pathway has suffered years of relative obscurity because tryptophan degradation, and its involvement in both physiology and major brain diseases, was viewed almost exclusively through the lens of the well ...
Schwarcz, Robert, Stone, Trevor W.
core   +1 more source

Determination of Monoethylene Glycol in Gas Condensate Samples by Microchip Micellar Electrokinetic Chromatography Integrated With Capacitively Coupled Contactless Conductivity Detection

ELECTROPHORESIS, EarlyView.
ABSTRACT This study describes the use of microchip micellar electrokinetic chromatography (MEKC) integrated with capacitively coupled contactless conductivity detection (C4D) for the determination of monoethylene glycol (MEG) in gas condensate samples.
Maurício M. L. Pereira, Kariolanda C. A. Rezende, Iris Medeiros Junior, Bruno Charles do Couto, Rogerio M. Carvalho, Claudimir L. do Lago, Wendell K. T. Coltro   +6 more
wiley   +1 more source

Pharmacological and Mechanistic Interventions for Cognitive Impairment Associated With Schizophrenia: A Review of Registered Clinical Trials

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Background Schizophrenia is characterized by positive, negative, and cognitive symptoms. Current pharmacological treatments often fail to address cognitive deficits. In this review of clinical trials, we aim to identify studies that explore neurobiological (non‐psychological) strategies to address Cognitive Impairment Associated with ...
Bahareh Peyrovian, Lena Palaniyappan, Theodore T. Kolivakis, Howard C. Margolese   +3 more
wiley   +1 more source

Efficacy of SSRIs on cognition of Alzheimer's disease patients treated with cholinesterase inhibitors. [PDF]

, 2010
Background: This study examines the joint effect on cognition of selective serotonin re-uptake inhibitors (SSRIs) and cholinesterase inhibitors (AChEIs) in depressed patients affected by Alzheimer’s disease (AD) living at home.
Bertoletti E, Conti M, Padovani A., Rozzini L., Trabucchi M, Vicini Chilovi B., Zanetti M   +6 more
core   +1 more source