Amaryllidaceae Alkaloids and Phenolic Acids Identification in Leucojum aestivum L. Plant Cultures Exposed to Different Temperature Conditions [PDF]
MoleculesAmaryllidaceae alkaloids are of notable pharmacological relevance. For instance, galanthamine is used in the treatment of Alzheimer’s disease, while other alkaloids (lycorine, crinine, etc.) derived from Amaryllidaceae plants are also of great interest ...
Agata Ptak +7 more
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Galanthamine Fails to Reverse P-gp-Mediated Paclitaxel Resistance in Ovarian Cancer Cell Lines [PDF]
BiomedicinesBackground: Ovarian cancer has the poorest prognosis of all gynecological malignancies, largely due to its chemoresistance, which poses significant treatment challenges. In this context, drug repurposing emerges as an innovative strategy that employs non-
Nélia Fonseca +4 more
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Synthesis of galanthamine [PDF]
ARKIVOC, 2001 The synthesis of (±)and (-)-galanthamine via 3,4-dihydro-6,7-dimethoxy-4'-oxo-spiro[5H]-2benzazepine-5,1'-[2]cyclohexene]-2(1H)-carboxylic acid ethyl ester (2) is described.
Laszlo Czollner +4 more
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The Occurrence and Bioactivities of Amaryllidaceae Alkaloids from Plants: A Taxonomy-Guided Genera-Wide Review [PDF]
PlantsThe distribution of Amaryllidaceae alkaloids, with a focus on their chemodiversity, has been reported previously, but not at a genera-wide diversity level.
G. David Lin +3 more
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Tissue-Specific Natural Synthesis of Galanthaminein Zephyranthes Species and Its Accumulation in Different In Vitro-Grown Organs Following Methyl Jasmonate Treatment [PDF]
PlantsGalanthamine is an immensely valuable alkaloid exhibiting anti-cancer and antiviral activity. The cultivation of plant tissues in in vitro conditions is a good source for the synthesis and enrichment of secondary metabolites of commercial interest.
Rukaya Syeed +9 more
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Alkaloid Profile Characterisation and Bioactivity Evaluation of Bolivian Hippeastrum Species (Amaryllidaceae) as Cholinesterase Inhibitors [PDF]
LifeAmaryllidaceae alkaloids from the Amaryllidoideae subfamily exhibit broad pharmacological activities, including neuroprotection and anticancer effects. Galanthamine is a key compound for Alzheimer’s therapy. The Hippeastrum genus, particularly in Bolivia,
María Lenny Rodríguez-Escobar +7 more
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Phytochemical and Cytotoxic Aspects of Amaryllidaceae Alkaloids in Galanthus Species: A Review [PDF]
PlantsThe genus Galanthus (Amaryllidaceae) currently contains 25 plant species naturally occurring in Europe and the Middle East region. These perennial bulbous plants possess well-known medicinal and ornamental qualities.
Borislav Georgiev +2 more
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Impact of rhizosphere quantitative microbiome and soil properties on alkaloid levels in Lycoris aurea herb [PDF]
Scientific ReportsLycoris aurea Herb is a plant renowned for its striking appearance and medicinal properties, particularly the production of alkaloids such as lycorine and galanthamine, which have therapeutic potential in treating diseases.
Guang-hua Liu +5 more
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Histochemical Localization and Cytotoxic Potential of Alkaloids in Phaedranassa lehmannii [PDF]
PlantsPlants of the subfamily Amaryllidoideae are a source of unique and bioactive alkaloids called Amaryllidaceae alkaloids. The study of their anticancer potential has intensified in recent years.
Lina M. Trujillo Chacón +6 more
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Alkaloid Profiling and Anti-Cholinesterase Potential of Three Different Genera of Amaryllidaceae Collected in Ecuador: Urceolina Rchb., Clinanthus Herb. and Stenomesson Herb. [PDF]
LifeEcuador is an important center of biodiversity for the plant subfamily Amaryllidoideae, known for its important bioactive molecules. This study aimed to assess the chemical and biological potential of four different Amaryllidoideae species collected in ...
Luciana R. Tallini +6 more
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