Pretraživanje tradicionalnih europskih ljekovitih biljaka na inhibiciju acetilkolinesteraze i butirilkolinesteraze [PDF]
, 2010 Acetylcholinesterase (AChE) inhibitors are widely used for the symptomatic treatment of Alzheimer’s disease (AD) to enhance central cholinergic transmission. On the other hand, butyrylcholinesterase (BuChE) inhibitors were reported to produce significant
A. Adsersen +16 more
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Composição química, atividades inibidora da acetilcolinesterase e antifúngica de Pera glabrata (Schott) Baill. (Euphorbiaceae) [PDF]
, 2009 Pera glabrata (Schott) Baill. was selected for this study after showing a preliminary positive result in a screening of Atlantic Forest plant species in the search for acetylcholinesterase inhibitors and antifungal compounds. The bioassays were conducted
BARBO, Fausto Erritto +6 more
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Plants, 2022 The inhibition of acetylcholinesterase (AChE) by cholinergic agents has been promoted as a potent strategy for treating and managing cognitive decline disorders.
Majid Rasool Kamli +3 more
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Impact of rhizosphere quantitative microbiome and soil properties on alkaloid levels in Lycoris aurea herb. [PDF]
Sci RepLycoris aurea Herb is a plant renowned for its striking appearance and medicinal properties, particularly the production of alkaloids such as lycorine and galanthamine, which have therapeutic potential in treating diseases.
Liu GH +5 more
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Phytochemical and Cytotoxic Aspects of Amaryllidaceae Alkaloids in Galanthus Species: A Review. [PDF]
Plants (Basel)The genus Galanthus (Amaryllidaceae) currently contains 25 plant species naturally occurring in Europe and the Middle East region. These perennial bulbous plants possess well-known medicinal and ornamental qualities.
Georgiev B, Sidjimova B, Berkov S.
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Cloning and characterization of a tyrosine decarboxylase involved in the biosynthesis of galanthamine in Lycoris aurea [PDF]
PeerJ, 2019 Background Galanthamine, one kind of Amaryllidaceae alkaloid extracted from the Lycoris species, is used in the treatment of Alzheimer’s disease. In regards to medical and economic importance, the biosynthesis and regulatory mechanism of the secondary ...
Rong Wang +6 more
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Natural AChE inhibitors from plants and their contribution to Alzheimer´s disease therapy [PDF]
, 2013 As acetylcholinesterase (AChE) inhibitors are an important therapeutic strategy in Alzheimer's disease, efforts are being made in search of new molecules with anti-AChE activity.
Alza, Natalia Paola +4 more
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Molecules, 2021 A combination of flash chromatography, solid phase extraction, high-performance liquid chromatography, and in vitro bioassays was used to isolate phytocomponents endowed with anticholinesterase activity in extract from Phyllanthus muellarianus ...
Marina Naldi +5 more
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Can phylogeny predict chemical diversity and potential medicinal activity of plants? A case study of amaryllidaceae [PDF]
, 2012 Background During evolution, plants and other organisms have developed a diversity of chemical defences, leading to the evolution of various groups of specialized metabolites selected for their endogenous biological function.
Birkholm, Trine +11 more
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Methyl 4-methyl-2-oxo-3,4-dihydrodibenzo[b,d]furan-4a(2H)-carboxylate
IUCrData, 2017 The title compound, C15H14O4, has structural similarities to the alkaloid galanthamine, used in the treatment of Alzheimer's disease. The structure consists of a fused three-ring system comprising benzene and cyclohexenone fused to a central furan ring ...
Yidong Jiang, Yifeng Wang
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