Results 141 to 150 of about 17,935 (273)

Programmed Cell Death in Chronic Rhinosinusitis

open access: yesClinical and Translational Allergy, Volume 16, Issue 6, June 2026.
ABSTRACT Chronic rhinosinusitis (CRS) is a prevalent upper respiratory condition characterized by a multifaceted etiology involving various cellular and molecular processes. In recent years, researchers have increasingly recognized the significance of different forms of programmed cell death (PCD), such as apoptosis and pyroptosis, in the pathological ...
Xingchen Liu   +5 more
wiley   +1 more source

Extracellular Vesicles as Drivers of Lung Endothelial Dysfunction in ARDS: Mechanisms and Therapeutic Opportunities

open access: yesComprehensive Physiology, Volume 16, Issue 3, June 2026.
This review summarizes how extracellular vesicles from diverse pulmonary and extrapulmonary sources contribute to endothelial dysfunction in ARDS and evaluates emerging endothelial‐targeted therapies for their potential to mitigate EV‐mediated pathogenic mechanisms.
Mohammed Yaman Al Matni   +3 more
wiley   +1 more source

The Supporting Role of Natural Products as Effective Adjuvants in Cancer Immunotherapy

open access: yeseFood, Volume 7, Issue 3, June 2026.
Natural products, as multi‐target and low‐toxicity adjuvants, enhance immune checkpoint inhibitor responses and reduce immune‐related adverse events through T cell reprogramming, microenvironment remodeling, and microbiota‐immune modulation. ABSTRACT Immune checkpoint inhibitors (ICIs) have revolutionized the treatment landscape of malignant tumors ...
Boyang Liu   +6 more
wiley   +1 more source

Effects of Total Flavonoids From Rubus chingii Hu on the Hypothalamic–Pituitary–Ovarian Axis and Inflammatory Response in Polycystic Ovary Syndrome Rats

open access: yesFood Science &Nutrition, Volume 14, Issue 6, June 2026.
RHF improves sex hormone secretion imbalance, restores the estrous cycle, inhibits ovarian hyperplasia and pathology, and reduces systemic and local ovarian inflammation in PCOS rats via enhancing HPO axis function and suppressing NLRP3 inflammasome signaling pathway activation.
Mengfan Peng   +7 more
wiley   +1 more source

Multifaceted Role of Extracellular Vesicles: Intercellular Messengers to Therapeutic Applications: A Narrative Review

open access: yesHealth Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aims Extracellular vesicles (EVs) are nanoscale carriers, including exosomes, microvesicles, and apoptotic bodies, that mediate intercellular communication by transporting proteins, nucleic acids, lipids, and metabolites. They regulate immunity, tissue repair, and cell differentiation.
Kajal Kamra   +7 more
wiley   +1 more source

Novel pyroptosis-independent functions of gasdermins

open access: yesSignal Transduction and Targeted Therapy, 2022
Ziran Qin, Fangfang Zhou, Long Zhang
openaire   +3 more sources

TCM‐Guided Targeted Therapies Against NLRP3 Inflammasome in NAFLD

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 6, June 2026.
This graphical abstract illustrates TCM syndrome differentiation‐guided targeted strategies against NLRP3 inflammasome‐mediated non‐alcoholic fatty liver disease (NAFLD). Metabolic dysfunction and gut‐liver axis dysregulation drive NAFLD progression, activating the NLRP3 inflammasome (comprising NLRP3, ASC, caspase‐1) to trigger cytokine release (IL‐1β,
Yanxia Zhang
wiley   +1 more source

Figure S6 from <i>In Situ</i> Delivery of Gasdermin E mRNA Promotes Antitumor Immunity via Creatine-Elicited Type I Interferon Signaling in Monocytes [PDF]

open access: gold
Hanjun Li   +9 more
openalex   +1 more source

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