Results 71 to 80 of about 175,164 (279)

Utilization of Genotyping-by-Sequencing (GBS) for Rice Pre-Breeding and Improvement: A Review

Life, 2022
Molecular markers play a crucial role in the improvement of rice. To benefit from these markers, genotyping is carried out to identify the differences at a specific position in the genome of individuals.
Vincent Pamugas Reyes, Justine Kipruto Kitony, Shunsaku Nishiuchi, Daigo Makihara, Kazuyuki Doi   +4 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Genomic Prediction in Maize Breeding Populations with Genotyping-by-Sequencing [PDF]

G3 Genes|Genomes|Genetics, 2013
Abstract Genotyping-by-sequencing (GBS) technologies have proven capacity for delivering large numbers of marker genotypes with potentially less ascertainment bias than standard single nucleotide polymorphism (SNP) arrays. Therefore, GBS has become an attractive alternative technology for genomic selection.
Crossa, Jose, Beyene, Yoseph, Kassa, Semagn, Pérez, Paulino, Hickey, John M, Chen, Charles, de Los Campos, Gustavo, Burgueño, Juan, Windhausen, Vanessa S, Buckler, Ed, Jannink, Jean-Luc, Lopez Cruz, Marco A, Babu, Raman   +12 more
openaire   +3 more sources

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Fine Mapping, Transcriptome Analysis, and Marker Development for Y2, the Gene That Conditions β-Carotene Accumulation in Carrot (Daucus carota L.)

G3: Genes, Genomes, Genetics, 2017
Domesticated carrots, Daucus carota subsp. sativus, are the richest source of β-carotene in the US diet, which, when consumed, is converted into vitamin A, an essential component of eye health and immunity.
Shelby Ellison, Douglas Senalik, Hamed Bostan, Massimo Iorizzo, Philipp Simon   +4 more
doaj   +1 more source

Comparisons of improved genomic predictions generated by different imputation methods for genotyping by sequencing data in livestock populations

Journal of Animal Science and Biotechnology, 2020
Background Genotyping by sequencing (GBS) still has problems with missing genotypes. Imputation is important for using GBS for genomic predictions, especially for low depths, due to the large number of missing genotypes.
Xiao Wang, Guosheng Su, Dan Hao, Mogens Sandø Lund, Haja N. Kadarmideen   +4 more
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Genomic resources for water yam (Dioscorea alata L.): analyses of EST sequences, De Novo sequencing and GBS libraries [PDF]

, 2015
Published online: 29 July ...
Asiedu, Robert, Bhattacharjee, R., Saski, C.A., Scheffler, Brian E.   +3 more
core   +4 more sources

Flexible and scalable genotyping-by-sequencing strategies for population studies [PDF]

BMC Genomics, 2014
De nombreux domaines essentiels à la production et à la recherche agricoles, tels que la sélection et la cartographie des caractères chez les plantes et le bétail, nécessitent des plates-formes de génotypage robustes et évolutives. Le génotypage par séquençage (GBS) est l'une de ces méthodes très adaptées aux organismes non humains.
Christopher Heffelfinger, Christopher Fragoso, Marlene Aparecida Moreno, John D. Overton, John P. Mottinger, Hongyu Zhao, Joe Tohmé, Stephen L. Dellaporta   +7 more
openaire   +3 more sources