Results 81 to 90 of about 4,652 (199)

NMR Solution Structure of the N‐Terminal GSPII Domain from the Thermus Thermophilus Traffic ATPase PilF and Reconstruction of its c‐di‐GMP Binding Capability

ChemBioChem, Volume 26, Issue 7, April 1, 2025.
GSPII‐A is the first of three consecutive GSPII domains of PilF from Thermus thermophilus and the only one that does not bind c‐di‐GMP. In this study we solve the structure of GSPII‐A and show the key factors hindering c‐di‐GMP binding. Through mutagenesis, we elucidate the minimal motif conservation needed for c‐di‐GMP recognition. Abstract The cyclic
Konstantin Neißner, Carolin Frohnapfel, Heiko Keller, Elke Duchardt‐Ferner, Vanessa Schneider, Zeinab Kamjou, Beate Averhoff, Jens Wöhnert   +7 more
wiley   +1 more source

Presence of a classical RRM-fold palm domain in Thg1-type 3'- 5'nucleic acid polymerases and the origin of the GGDEF and CRISPR polymerase domains

Biology Direct, 2010
Background Almost all known nucleic acid polymerases catalyze 5'-3' polymerization by mediating the attack on an incoming nucleotide 5' triphosphate by the 3'OH from the growing polynucleotide chain in a template dependent or independent manner. The only
Aravind L, Iyer Lakshminarayan M, Anantharaman Vivek   +2 more
doaj   +1 more source

c-di-AMP: An essential molecule in the signaling pathways that regulate the viability and virulence of gram-positive bacteria [PDF]

, 2017
Signal transduction pathways enable organisms to monitor their external environment and adjust gene regulation to appropriately modify their cellular processes.
Cho, Kyu Hong, Fahmi, Tazin, Port, Gary C   +2 more
core   +2 more sources

Co‐Existence Slows Diversification in Experimental Populations of E. coli and P. fluorescens

Environmental Microbiology, Volume 27, Issue 2, February 2025.
Escherichia coli and Pseudomonas fluorescens were cultured in monoculture and co‐culture for 8 weeks. Both species diversified in monoculture, while sequencing revealed mutations in P. fluorescens that were enriched in co‐culture with E. coli. A sequencing‐based invasion assay of 16S amplicons revealed that mutations in the PFLU_1661 gene confer the ...
Gareth Howells, Aysha L. Sezmis, Christopher Blake, Michael J. McDonald   +3 more
wiley   +1 more source

Characterization and analysis of a novel diguanylate cyclase PA0847 from Pseudomonas aeruginosa PAO1

Infection and Drug Resistance, 2019
Yan Zhang,1,2 Jiayi Guo,1 Ning Zhang,2 Wensu Yuan,2 Zhi Lin,2 Weidong Huang11Department of Biochemistry and Molecular Biology, School of Basic Medicine, Ningxia Medical University, Yinchuan 750004, People’s Republic of China; 2School of Life ...
Zhang Y, Guo J, Zhang N, Yuan W, Lin Z, Huang W   +5 more
doaj  

A GGDEF and EAL domain-containing protein in Pseudomonas syringae pv. actinidiae regulates virulence via its diguanylate cyclase activity

Phytopathology Research
Kiwifruit bacterial canker (KBC), caused by Pseudomonas syringae pv. actinidiae (Psa), poses a severe threat to the global kiwifruit industry, highlighting the urgent need to elucidate its pathogenic mechanisms. Cyclic diguanylate monophosphate (c-di-GMP)
Yudi Wang, Mingming Yang, Jinfang Zhou, Xianwei Xie, Jiabing Ma, Yao Wang, Xihui Shen, Lili Huang   +7 more
doaj   +1 more source

Identification of a cyclic-di-GMP-modulating response regulator that impacts biofilm formation in a model sulfate reducing bacterium

Frontiers in Microbiology, 2014
We surveyed the eight putative cyclic-di-GMP-modulating response regulators (RRs) in Desulfovibrio vulgaris Hildenborough that are predicted to function via two-component signaling.
Lara eRajeev, Eric G Luning, Sara eAltenburg, Grant Matthew Zane, Edward E Baidoo, Michela eCatena, Jay D Keasling, Jay D Keasling, Judy D Wall, Matthew W Fields, Aindrila eMukhopadhyay   +10 more
doaj   +1 more source

DhhP, a Cyclic di-AMP Phosphodiesterase of Borrelia burgdorferi, Is Essential for Cell Growth and Virulence [PDF]

, 2014
Cyclic di-AMP (c-di-AMP) is a recently discovered second messenger in bacteria. Most of work on c-di-AMP signaling has been done in Gram-positive bacteria, firmicutes, and actinobacteria, where c-di-AMP signaling pathways affect potassium transport, cell
Fang, Xin, Gomelsky, Mark, Lawlis, Gavin B., Lou, Yongliang, Troxell, Bryan, Yang, X. Frank, Ye, Meiping, Zhang, Jun-Jie, Zhou, Yan   +8 more
core   +1 more source

Constructing a Novel Disease Resistance Mechanism Model for Cruciferous Crops: An Example From Black Rot

Molecular Plant Pathology, Volume 26, Issue 2, February 2025.
This review explores the resistance mechanisms of cruciferous crops against Xanthomonas campestris pv. campestris, providing insights into improving disease resistance and enhancing agricultural productivity. ABSTRACT Cruciferous crops are essential components of global agricultural production due to their rich nutritional value and extensive economic ...
Haojie Dai, Linli Hu, Jie Wang, Zhibin Yue, Jue Wang, Tongyan Chen, Jinbao Li, Tingting Dou, Jihua Yu, Zeci Liu   +9 more
wiley   +1 more source

Regulation of biofilm formation in Salmonella typhimurium and Escherichia coli Nissle 1917 [PDF]

, 2011
Bacteria have the ability to grow in cell communities designated biofilms. This mode of growth is widespread and offers numerous advantages to the bacteria in terms of survival, persistence and propagation.
Monteiro, Cláudia
core   +1 more source