Results 11 to 20 of about 1,835 (174)

Astroglial Excitability and Gliotransmission: An Appraisal of Ca as a Signalling Route

open access: yesASN Neuro, 2012
Astroglial cells, due to their passive electrical properties, were long considered subservient to neurons and to merely provide the framework and metabolic support of the brain.
Robert Zorec   +5 more
doaj   +9 more sources

Modulation of Synaptic Plasticity by Glutamatergic Gliotransmission: A Modeling Study [PDF]

open access: yesNeural Plasticity, 2016
Glutamatergic gliotransmission, that is, the release of glutamate from perisynaptic astrocyte processes in an activity-dependent manner, has emerged as a potentially crucial signaling pathway for regulation of synaptic plasticity, yet its modes of ...
Maurizio De Pittà, Nicolas Brunel
doaj   +9 more sources

Trpv4 Mediates Hypotonic Inhibition of Central Osmosensory Neurons via Taurine Gliotransmission

open access: yesCell Reports, 2018
Summary: The maintenance of hydromineral homeostasis requires bidirectional detection of changes in extracellular fluid osmolality by primary osmosensory neurons (ONs) in the organum vasculosum laminae terminalis (OVLT). Hypertonicity excites ONs in part 
Masha Prager-Khoutorsky   +2 more
exaly   +4 more sources

Gliotransmission: Beyond Black-and-White [PDF]

open access: yesThe Journal of Neuroscience, 2018
Astrocytes are highly complex cells with many emerging putative roles in brain function. Of these, gliotransmission (active information transfer from glia to neurons) has probably the widest implications on our understanding of how the brain works: do ...
Iaroslav Savtchouk   +3 more
core   +5 more sources

Looks Can Be Deceiving: Reconsidering the Evidence for Gliotransmission [PDF]

open access: yesNeuron, 2014
Gliotransmission, a process involving active vesicular release of glutamate and other neurotransmitters by astrocytes, is thought to play a critical role in many brain functions. A new paper by Nedergaard et al.
Sloan, Steven A., Barres, Ben A.
core   +4 more sources

Glutamatergic and GABAergic gliotransmission [PDF]

open access: yes, 2015
Glutamatergic and GABAergic gliotransmission is a compilation of studies on the ability of glial cells to release glutamate by exocytosis and GABA by bestrophin 1 channel.
Ormel, Lasse
core   +4 more sources

Modelling the modulation of cortical Up-Down state switching by astrocytes.

open access: yesPLoS Computational Biology, 2022
Up-Down synchronization in neuronal networks refers to spontaneous switches between periods of high collective firing activity (Up state) and periods of silence (Down state).
Lisa Blum Moyse, Hugues Berry
doaj   +2 more sources

Gliotransmission Orchestrates Neuronal Type-specific Axon Regeneration [PDF]

open access: yes, 2022
Why closely related neuronal types differ in their axon regenerative abilities remains elusive. Here, I demonstrate gliotransmission determines such a difference in Drosophila larval sensory neurons.
Wang, Fei
core   +3 more sources

Active dendrites regulate the impact of gliotransmission on rat hippocampal pyramidal neurons [PDF]

open access: yesProceedings of the National Academy of Sciences, 2016
An important consequence of gliotransmission, a signaling mechanism that involves glial release of active transmitter molecules, is its manifestation as N-methyl-D-aspartate receptor (NMDAR)-dependent slow inward currents in neurons.
Ashhad, Sufyan, Narayanan, Rishikesh
core   +3 more sources

Gliotransmission and the tripartite synapse

open access: yes, 2012
In the last years, the classical view of glial cells (in particular of astrocytes) as a simple supportive cell for neurons has been replaced by a new vision in which glial cells are active elements of the brain.
Cali, C.
core   +7 more sources

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