Results 41 to 50 of about 1,835 (174)
Insulin regulates astrocyte gliotransmission and modulates behavior [PDF]
Journal of Clinical Investigation, 2018 Complications of diabetes affect tissues throughout the body, including the central nervous system. Epidemiological studies show that diabetic patients have an increased risk of depression, anxiety, age-related cognitive decline, and Alzheimer's disease.
Weikang Cai +10 more
openaire +2 more sources
Glioactive ATP controls BDNF recycling in cortical astrocytes
Communicative & Integrative Biology, 2017 We have recently reported that long-term memory retention requires synaptic glia for proBDNF uptake and recycling. Through the recycling course, glial cells release endocytic BDNF, a mechanism that is activated in response to glutamate via AMPA and ...
Beatrice Vignoli, Marco Canossa
doaj +1 more source
THE CAJAL SCHOOL AND THE PHYSIOLOGICAL ROLE OF ASTROCYTES: A WAY OF THINKING
Frontiers in Neuroanatomy, 2014 Cajal is widely recognized by the scientific community for his important contributions to our knowledge of the neuronal organization of the nervous system.
Marta eNavarrete +2 more
doaj +1 more source
Frontiers in Computational Neuroscience, 2020 Recent research in neuroscience indicates the importance of tripartite synapses and gliotransmission mediated by astrocytes in neuronal system modulation.
Kerstin Lenk +10 more
doaj +1 more source
NEURON-GLIA NETWORKS: INTEGRAL GEAR OF BRAIN FUNCTION
Frontiers in Cellular Neuroscience, 2014 Astrocytes, the most abundant glial cell in the brain, play critical roles in metabolic and homeostatic functions of the Nervous System; however, their participation in coding information and cognitive processes has been largely ignored.
Gertrudis ePerea +2 more
doaj +1 more source
Astrocytes as Guardians of Neuronal Excitability: Mechanisms Underlying Epileptogenesis
Frontiers in Neurology, 2020 Astrocytes are key homeostatic regulators in the central nervous system and play important roles in physiology. After brain damage caused by e.g., status epilepticus, traumatic brain injury, or stroke, astrocytes may adopt a reactive phenotype.
Quirijn P. Verhoog +6 more
doaj +1 more source
Gliotransmission modulates baseline mechanical nociception [PDF]
, 2020 Pain is a physiological and adaptive process which occurs to protect organisms from tissue damage and extended injury. Pain sensation beyond injury, however, is a pathological process which is poorly understood.
Sally R Mciver +2 more
core
Amyloid pathology disrupts gliotransmitter release in astrocytes.
PLoS Computational Biology, 2022 Accumulation of amyloid-beta (Aβ) is associated with synaptic dysfunction and destabilization of astrocytic calcium homeostasis. A growing body of evidence support astrocytes as active modulators of synaptic transmission via calcium-mediated ...
Anup Gopalakrishna Pillai +1 more
doaj +1 more source
Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing
Advanced Science, EarlyView.Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale +6 more
wiley +1 more source
New Tools for Investigating Astrocyte-to-Neuron Communication
Frontiers in Cellular Neuroscience, 2013 Grey matter protoplasmic astrocytes extend very thin processes and establish close contacts with synapses. It has been suggested that the release of neuroactive gliotransmitters at the tripartite synapse contributes to information processing.
Dongdong eLi +4 more
doaj +1 more source