Results 21 to 30 of about 1,835 (174)
Astrocyte Calcium Signal and Gliotransmission in Human Brain Tissue [PDF]
Brain function is recognized to rely on neuronal activity and signaling processes between neurons, whereas astrocytes are generally considered to play supportive roles for proper neuronal function. However, accumulating evidence indicates that astrocytes
Perea, Gertrudis +8 more
core +4 more sources
Astroglial excitability operates through increases in Ca 2+ cyt (cytosolic Ca 2+ ), which can lead to glutamatergic gliotransmission. In parallel fluctuations in astrocytic Na + cyt (cytosolic Na + ) control metabolic neuronal-glial signalling, most ...
Reno C Reyes +2 more
doaj +2 more sources
Calcium signaling and gliotransmission in normal versus reactive astrocytes [PDF]
A prominent area of neuroscience research over the past 20 years has been the acute modulation of neuronal synaptic activity by Ca2+-dependent release of the transmitters ATP, D-serine, and glutamate (called gliotransmitters) by astrocytes.
Cendra eAgulhon +5 more
doaj +3 more sources
Editorial: Advances in volume electron microscopy for brain imaging: methods, applications, and affordability [PDF]
Corrado Calì +2 more
doaj +2 more sources
Physiology of Astroglia: Channels, Receptors, Transporters, Ion Signaling and Gliotransmission
Astrocytes can be defined as glia inhabiting the nervous system with the main function in the maintenance of nervous tissue homeostasis. Classified into several types according to their morphological appearance, many of astrocytes form a reticular ...
Parpura, V +1 more
core +10 more sources
Intracellular Ca2+-signaling in astrocytes is instrumental for their brain “housekeeping” role and astroglial control of synaptic plasticity. An important source for elevating the cytosolic Ca2+ level in astrocytes is a release from endoplasmic reticulum
Yuriy Pankratov, Ulyana Lalo
exaly +3 more sources
Editorial: The legacy of Sherrington and Adrian Nobel Prize: non-neuronal cells in information processing [PDF]
Wuhyun Koh, Zhuofan Lei
doaj +2 more sources
Calcium signaling in astrocytes and gliotransmitter release
Glia are as numerous in the brain as neurons and widely known to serve supportive roles such as structural scaffolding, extracellular ionic and neurotransmitter homeostasis, and metabolic support.
Julianna Goenaga +3 more
doaj +1 more source
Swelling Gliotransmission by SWELL1 Channels [PDF]
Astrocytes release glutamate, which can modulate nearby synapses, but how this release is accomplished remains debated. In this issue of Neuron, Yang et al. (2019) show that the volume-regulated anion channel Swell1 in astrocytes mediates the release of glutamate and impacts synaptic transmission, learning and memory, and neurotoxicity.
Paulo, Kofuji, Alfonso, Araque
openaire +2 more sources
Calcium Signals in Astrocyte Microdomains, a Decade of Great Advances
The glial cells astrocytes have long been recognized as important neuron-supporting elements in brain development, homeostasis, and metabolism. After the discovery that the reciprocal communication between astrocytes and neurons is a fundamental ...
Annamaria Lia +12 more
doaj +1 more source

