Results 91 to 100 of about 38,797 (256)

The effect of eight weeks of aerobic training on GLUT4 and AS160 protein levels and insulin resistance in the EDL muscle of type 2 diabetic rats [PDF]

open access: yesمجله علوم پزشکی فیض (پیوسته)
Background and Aim: One of the most significant complications of type 2 diabetes is the disruption of glucose transport mechanisms in cell membranes, with GLUT4 and AS160 proteins playing crucial roles in this process.
Farkhondeh Garavandpour   +2 more
doaj  

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

open access: yesBritish Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli   +7 more
wiley   +1 more source

Exercise-induced protection against insulin resistance and type 11 diabetes : the role of calcium

open access: yes, 2008
Includes abstract.Includes bibliographical references (p. 89-106).Regular exercise protects individuals against developing insulin resistance and type II diabetes.
Smith, James Antony Harris
core  

Exercise, GLUT4, and skeletal muscle glucose uptake

open access: yes, 2013
an important fuel for contracting muscle, and normal glucose metabolism is vital for health. Glucose enters the muscle cell via facilitated diffusion through the GLUT4 glucose transporter which translocates from intracellular storage depots to the plasma
Erik A. Richter   +3 more
core   +1 more source

Hypercortisolism: Causes, Consequences and Clinical Significance – A Review of Pathophysiology

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Hypercortisolism or Cushing syndrome is a heterogeneous clinical spectrum caused by chronic glucocorticoid excess, ranging from exogenous Cushing syndrome to rare endogenous aetiologies and the increasingly recognised entity of mild autonomous cortisol secretion (MACS). Physiological cortisol production is tightly regulated by the hypothalamic–
Mohamed Eldib   +3 more
wiley   +1 more source

Diagnosis and management of equine metabolic syndrome

open access: yesEquine Veterinary Education, EarlyView.
Summary Equine metabolic syndrome (EMS) is a prevalent endocrine disorder that increases the risk of hyperinsulinaemia‐associated laminitis (HAL), the most common and clinically significant form of laminitis. The central pathological feature of EMS is insulin dysregulation (ID), which encompasses basal or postprandial hyperinsulinaemia and tissue ...
F. R. Bertin
wiley   +1 more source

Hypoglycemic Activity of Curcuma mangga Val. Extract via Modulation of GLUT4 and PPAR-γ mRNA Expression in 3T3-L1 Adipocytes

open access: yesJournal of Experimental Pharmacology, 2020
Dwiyati Pujimulyani,1 Wisnu Adi Yulianto,1 Astuti Setyowati,1 Seila Arumwardana,2 Hanna Sari Widya Kusuma,2 Ika Adhani Sholihah,2 Rizal Rizal,2,3 Wahyu Widowati,4 Ali Maruf5 1Faculty of Agroindustry, University of Mercu Buana Yogyakarta, Yogyakarta 55753,
Pujimulyani D   +8 more
doaj  

Insulin-regulated trafficking of GLUT4 requires ubiquitination

open access: yes, 2010
A major consequence of insulin binding its receptor on fat and muscle cells is translocation of the facilitative glucose transporter GLUT4 from an intracellular store to the cell surface where it serves to clear glucose from the bloodstream.
Lamb, C.A.   +9 more
core   +1 more source

From hepatic to hematopoietic: LRH‐1's expanding cellular repertoire to the immune system

open access: yesThe FEBS Journal, EarlyView.
The nuclear receptor LRH‐1 is a well‐characterized regulator of endodermal tissue. Yet, increasing evidence indicates that LRH‐1, although expressed at low levels, is also a critical regulator of the hematopoietic system. LRH‐1 regulates the immune system by contributing to immune cell‐specific functions.
Lukas Meisinger   +3 more
wiley   +1 more source

Constitutive versus Regulated Traffic of GLUT4

open access: yes, 2009
Glucose transporter GLUT4 allows glucose uptake into muscle and adipose cells. Insulin promotes recruitment and plasma membrane insertion of GLUT4 vesicles that can recycle constitutively.
Randhawa, Varinder
core   +2 more sources

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