Results 41 to 50 of about 8,652 (209)
Induction of Connexin-hemichannel Opening
Bio-Protocol, 2014 Connexins (Cxs) are integral membrane proteins of vertebrates that associate to form hexameric transmembrane channels, named hemichannels. Twenty-one Cx types have been described, which are named according to their molecular weight.
Andrea Puhar, Philippe Sansonetti
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Connexin-based gap junction hemichannels: Gating mechanisms [PDF]
, 2005 Connexins (Cxs) form hemichannels and gap junction channels. Each gap junction channel is composed of two hemichannels, also termed connexons, one from each of the coupled cells.
Sáez, Juan C. +4 more
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Connexin 43 Channels in Osteocytes Regulate Bone Responses to Mechanical Unloading
Frontiers in Physiology, 2020 Connexin (Cx) 43 forms gap junctions and hemichannels that mediate communication between osteocytes and adjacent cells or the extracellular environment in bone, respectively.
Dezhi Zhao +10 more
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The role of pannexin hemichannels in inflammation and regeneration [PDF]
Frontiers in Physiology, 2014 Tissue injury involves coordinated systemic responses including inflammatory response, targeted cell migration, cell-cell communication, stem cell activation and proliferation, and tissue inflammation and regeneration. The inflammatory response is an important prerequisite for regeneration.
Helen P. Makarenkova +2 more
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Pitfalls when examining gap junction hemichannels: interference from volume-regulated anion channels [PDF]
, 2006 Human HeLa cells transfected with mouse connexin45 were used to explore the experimental conditions suitable to measure currents carried by gap junction hemichannels.
Weingart, Robert, Bader, Patrick
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Connexin 43 Hemichannels Are Permeable to ATP [PDF]
The Journal of Neuroscience, 2008 Astrocytes are electrically nonexcitable cells that communicate by means of Ca2+signaling. Long-distance intercellular Ca2+waves are initiated by release of ATP and activation of purinergic receptors on nearby cells. Previous studies have implicated connexin 43 (Cx43) in ATP release, but definitive proof that ATP exits through Cx43 hemichannels does ...
Jian, Kang +6 more
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Redox Biology, 2016 Connexin (Cx) hemichannels regulate many cellular processes with little information available regarding their mechanisms. Given that many pathological factors that activate hemichannels also disrupts the integrity of cellular junctions, we speculated a ...
Yuan Chi +6 more
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Characterization of Nonjunctional Hemichannels in Caterpillar Cells [PDF]
Journal of Insect Science, 2011 Recent studies have demonstrated that hemichannels, which form gap junctions when paired from apposing cells, may serve additional roles when unpaired including cell adhesion and paracrine communication. Hemichannels in mammals are formed by connexins or pannexins, while in insects they are formed by pannexin homologues termed innexins.
Luo, Kaijun, Turnbull, Matthew W.
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Mechanosensitivity of gap junction hemichannels
, 2005 Most gap junction hemichannels stay in the closed state before they dock to each other and form complete functional channels. Some exceptions, Connexin 46 (Cx46), Cx50 and pannexin 1, can form functional hemichannels in nonjunctional membranes.
Bao, Li
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Regulation of Cx45 hemichannels mediated by extracellular and intracellular calcium [PDF]
, 2012 Connexin45 (Cx45) hemichannels (HCs) open in the absence of Ca(2+) and close in its presence. To elucidate the underlying mechanisms, we examined the role of extra- and intracellular Ca(2+) on the electrical properties of HCs.
Weingart, Robert +2 more
core +2 more sources