Cyclic nucleotide permeability through unopposed connexin hemichannels
Cyclic AMP is a well-known intracellular and intercellular second messenger. The membrane permeability of such molecules has potential importance for autocrine like or paracrine-like delivery.
Virginijus eValiunas
doaj +1 more source
Connexin 43 hemichannels and related diseases
Abstract Connexin 43 (Cx43) protein forms hemichannels (connexons) and gap junctions, with hemichannels consisting of six Cx43 molecules and gap junctions formed by two hemichannels. While gap junctions are prevalent in organs like the heart and liver, hemichannels are found in specific cell types, such as astrocytes and osteocytes ...
Yanfeng Zhang +2 more
openaire +2 more sources
Nanomechanics of Hemichannel Conformations [PDF]
Fei Liu +3 more
openaire +1 more source
Mechanisms of permselectivity of connexin hemichannels to small molecules. [PDF]
Lovatt A, Butler J, Dale N.
europepmc +2 more sources
CO<sub>2</sub>-dependent opening of connexin 43 hemichannels. [PDF]
Dospinescu VM +7 more
europepmc +1 more source
The Dual Role of Connexins in Stroke, Neurotrauma, Neurodegenerative and Psychiatric Disorders: A Global Systematic Review. [PDF]
Rodkin S +6 more
europepmc +1 more source
Connexin 26 in Hearing Health and Disease: StructuralFoundations, Mutation Mechanisms, and Therapeutic Perspectives. [PDF]
Qiu W, Schneider K, Guo Y.
europepmc +1 more source
Inhibition of connexin hemichannels protects retinal ganglion cells against ocular nerve injury. [PDF]
Du Y +6 more
europepmc +1 more source
Glial Connexin-43 Is a Pathogenic Mechanism Promoting Gut Inflammation in Postoperative Ileus Induced by Gut Surgical Manipulation With Potential Relevance to Humans. [PDF]
Chaudhuri S +13 more
europepmc +1 more source

