Results 191 to 200 of about 475,440 (346)
United European Gastroenterology Journal, EarlyView.ABSTRACT Background Cholangiocarcinoma presents a global health challenge due to its increasing incidence and poor prognosis, primarily resulting from delayed diagnosis. There is an urgent need for a reliable biomarker to enhance early detection. Materials and Methods Patients with cholangiocarcinoma were enrolled into three cohorts: a discovery set (n
Lichieh Julie Chu +6 more
wiley +1 more source
Heparan Sulfate Proteoglycans in Infection
, 2011 To cause infections, microbial pathogens elaborate a multitude of factors that interact with host components. Using these host–pathogen interactions to their advantage, pathogens attach, invade, disseminate, and evade host defense mechanisms to promote their survival in the hostile host environment.
Pyong Woo Park, Allison H. Bartlett
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A Frailty‐Based Plasma Proteomic Signature Capturing Overall Health and Well‐Being in Older Adults
Aging Cell, EarlyView.We derived a 25‐protein blood‐based frailty signature (proteomic frailty index, pFI) predictive of the cumulative frailty index. The pFI was validated across independent cohorts and was significantly associated with physical, clinical, and cognitive function, as well as incident mortality and dementia, highlighting its potential as a biomarker of ...
Sanish Sathyan +13 more
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Heparan sulfate proteoglycans of human lung fibroblasts. Occurrence of distinct membrane, matrix and secreted forms [PDF]
, 1986 V Lories +3 more
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Aging Cell, EarlyView.The maintenance of aging mesenchymal stem cells (MSCs) on extracellular matrix synthesized by human amniotic fluid‐derived pluripotent stem cells (ECM Plus), a young microenvironment, remarkably restored their quantity and quality along with up‐regulating HLA‐DR and CD74.
Aaron O. Gonzalez +10 more
wiley +1 more source
Andrology, EarlyView.Abstract Background Long‐acting gonadotropin‐releasing hormone (GnRH) agonists are commonly used for fertility control in male dogs. Their effect on testicular histomorphology has not been clarified. Objectives To elucidate the mechanisms underlying androgen withdrawal in response to long‐acting GnRH agonist deslorelin 4.7 mg treatment on testicular ...
Aykut Gram +5 more
wiley +1 more source
Basement membrane-like matrix of teratocarcinoma-derived endodermal cells: presence of laminin and heparan sulfate in the matrix at points of attachment to cells. [PDF]
, 1983 Ilmo Leivo
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Anti‐PF4 disorders: Pathogenesis, diagnosis and treatment
British Journal of Haematology, EarlyView.Anti‐platelet factor 4 (PF4) disorders include heparin‐induced thrombocytopenia (HIT) and vaccine‐induced immune thrombocytopenia and thrombosis (VITT)/VITT‐like disorders. The formation of immunoglobulin G (IgG)/PF4 immune complexes facilitates uncontrolled activation of platelets, neutrophils and monocytes via IgG‐mediated Fcγ receptor binding.
Megan V. Preece +3 more
wiley +1 more source
Clinical Genetics, EarlyView.We report an individual with mucopolysaccharidosis type IIIB and chronic pancytopenia. Hematological studies in a mouse model revealed microcytic anemia and decreased monocyte count. Hence, pancytopenia is thought to be secondary to mucopolysaccharidosis type IIIB, and we suggest that a complete blood count should be included in the clinical ...
Éliane Beauregard‐Lacroix +3 more
wiley +1 more source
The effect of beta-xylosides on heparan sulfate synthesis by SV40-transformed Swiss mouse 3T3 cells.
, 1979 Laurance S. Johnston, J.M. Keller
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