Results 221 to 230 of about 223,415 (361)

Deubiquitination of Histone H2B by a Yeast Acetyltransferase Complex Regulates Transcription

open access: hybrid, 2004
J. Daniel   +6 more
openalex   +1 more source

Pan‐Epigenetic Age Prediction in Mammals

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
Across > 1000 human and mouse epigenomes, histone modifications and DNA methylation undergo coordinated, cross‐tissue remodeling at shared genes. ABSTRACT Epigenetic remodeling is a hallmark of aging, yet which epigenetic layers are most affected during aging—and the extent to which they are interrelated—is not well understood.
Zane Koch, Adam Li, Trey Ideker
wiley   +1 more source

Targeting the Menin–KMT2A interaction in leukemia: Lessons learned and future directions

open access: yesInternational Journal of Cancer, Volume 158, Issue 2, Page 342-356, 15 January 2026.
Abstract Chromosomal rearrangements involving the Mixed Lineage Leukemia gene (MLL1, KMT2A) are defining a genetically distinct subset in about 10% of human acute leukemias. Translocations involving the KMT2A‐locus at chromosome 11q23 are resulting in the formation of a chimeric oncogene, where the N‐terminal part of KMT2A is fused to a variety of ...
Florian Perner   +3 more
wiley   +1 more source

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