Results 241 to 250 of about 35,141 (364)

Uhrf1 downregulation promotes β‐cell dedifferentiation by decreasing Foxo1 expression in type 2 diabetes

open access: yesJournal of Diabetes Investigation, EarlyView.
This finding reveals the important role of Uhrf1 in the β‐cell dedifferentiation of T2D, providing a potential target for its treatment. ABSTRACT Background Islet β‐cell dedifferentiation is a major pathological mechanism of type 2 diabetes (T2D). Forkhead box o1 (Foxo1) is a master regulator of β‐cell dedifferentiation.
Lanfang Fu   +3 more
wiley   +1 more source

Regulation of Global Acetylation in Mitosis through Loss of Histone Acetyltransferases and Deacetylases from Chromatin

open access: hybrid, 2001
Michael J. Kruhlak   +7 more
openalex   +1 more source

Previously uncharacterized histone acetyltransferases implicated in mammalian spermatogenesis [PDF]

open access: green, 2002
Bruce T. Lahn   +6 more
openalex   +1 more source

Regulatory and retrograde signaling networks in the chlorophyll biosynthetic pathway

open access: yesJournal of Integrative Plant Biology, Volume 67, Issue 4, Page 887-911, April 2025.
This review summarizes the regulatory mechanisms that underlie chlorophyll synthesis, including (1) factors that control the activity and stability of tetrapyrrole biosynthesis enzymes, (2) transcriptional and post‐translational regulation of the tetrapyrrole biosynthesis pathway, and (3) the complex roles of tetrapyrrole‐mediated retrograde signaling ...
Yuhong Li   +6 more
wiley   +1 more source

Dysfunction of duplicated pair rice histone acetyltransferases causes segregation distortion and an interspecific reproductive barrier. [PDF]

open access: yesNat Commun
Liao B   +20 more
europepmc   +1 more source

TaSED interacts with TaSPA synergistically regulating SDS‐sedimentation volume in bread wheat

open access: yesJournal of Integrative Plant Biology, EarlyView.
Wheat TaSED is a positive regulator of SDS‐sedimentation volume, an indicator of gluten strength and thus baking properties. TaSED interacts with the transcription factor TaSPA regulating wheat storage protein gene expression, altering protein composition and affecting SDS‐sedimentation volume, providing a valuable genetic resource for improving wheat ...
Shanshan Zhai   +13 more
wiley   +1 more source

Two Different Drosophila ADA2 Homologues Are Present in Distinct GCN5 Histone Acetyltransferase-Containing Complexes [PDF]

open access: green, 2002
Selen C. Muratoglu   +11 more
openalex   +1 more source

Natural Antisense Transcript‐Mediated Regulation of HOXA10‐AS in Oral Squamous Cell Carcinoma

open access: yesJournal of Oral Pathology &Medicine, Volume 54, Issue 4, Page 217-231, April 2025.
ABSTRACT Background The oncogenic role of HOXA10‐AS and HOXA10 in cancer has been well documented. However, the epigenetic role of HOXA10 and the natural antisense‐mediated regulation of HOXA10‐AS in oral squamous cell carcinoma progression is not understood.
Kanaka Sai Ram Padam   +3 more
wiley   +1 more source

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