Results 181 to 190 of about 4,008 (211)

Positive Feedback Loop of Histone Lactylation-Driven HNRNPC Promotes Autophagy to Confer Pancreatic Ductal Adenocarcinoma Gemcitabine Resistance. [PDF]

Adv Sci (Weinh)
Huang XT, Chen J, Zhu EL, Ma MJ, Yu YY, Zhu YQ, Ye JY, Xie JZ, Zhao ZY, Yin XY.   +9 more
europepmc   +1 more source

The Multiple Roles of Lactate in the Skeletal Muscle [PDF]

Bartoloni, Bianca, Gamberi, Tania, Mannelli, Michele   +2 more
core  

Exercise-induced histone lactylation in monocyte-derived macrophages restores cardiac immune homeostasis and function in sepsis-induced cardiomyopathy. [PDF]

Nat Commun
Sun S, Lai C, Huang C, Ren X, Zhang T, Zou J, Tong Y, Zhou Q, Lu J, Shen Z, Chen W, Wang R, Rabrenovic N, Wang X, Ma B, Qian J, Fu G, Shang M.   +17 more
europepmc   +1 more source

MPC-mediated lactate production drives histone lactylation in dendritic cells to affect tumor progression and immunotherapy. [PDF]

Cell Mol Life Sci
Zhang B, Xu A, Wang H, Yan W, Zhang Q, Wang S.   +5 more
europepmc   +1 more source

Mechanisms of FOXK1-regulated glycolipid metabolism in mediating TOX-induced histone lactylation to promote CD8⁺ T cell exhaustion in high-grade serous ovarian cancer. [PDF]

Sci Rep
Li M.
europepmc   +1 more source

Histone Lactylation Couples FSH-Driven Lactate Metabolism to Mitochondrial Biogenesis by Enhancing HDAC4-Mediated Deacetylation of PGC-1α in Granulosa Cells. [PDF]

Research (Wash D C)
Wu G, Chen M, Li C, Wei M, Pan Y, He T, Liu Z, Li H, Zhang C, Zhang JQ, Sheng Y, Liu Y, Liu H, Shen M.   +13 more
europepmc   +1 more source

Hypoxic glycolysis-driven histone lactylation activates NHE7 to promote endometrial cancer progression via COX6C-mediated endoplasmic reticulum stress. [PDF]

Apoptosis
Yang S, Wu T, Cao Z, Chen Z, Ma Y, Wang T, Qian L, Huang X.   +7 more
europepmc   +1 more source

Exploration of biomarkers associated with histone lactylation modification in spinal cord injury. [PDF]

Front Genet
Sun Y, Gao J, Jing J.
europepmc   +1 more source

Histone lactylation-induced GLI3 activation drives macrophage M1 polarization and exosomal SERPINE1 release in abdominal aortic aneurysm progression. [PDF]

Cell Death Discov
Yuan K, Liu J, Chen G, Wang P, Wei L.
europepmc   +1 more source

Hypoxia-Induced Histone Lactylation Drives Cisplatin Resistance in Bladder Cancer by Promoting RBM15-Dependent m⁶A Methylation of IGFBP3. [PDF]

Research (Wash D C)
Sun J, Shi Y, Yu K, Huang S, Lu D, Niu X, Li Y, Wang F, Ma X, Li J, Liu X, Xie L, Huang H, Liu B.   +13 more
europepmc   +1 more source