Results 31 to 40 of about 65,477 (225)

Sequence-specific targeting of nuclear signal transduction pathways by homeodomain proteins [PDF]

, 1995
Cells translate extracellular signals into specific programs of gene expression that reflect their developmental history or identity. We present evidence that one way this interpretation may be performed is by cooperative interactions between serum ...
Grueneberg, D. A., Simon, K. J., Brennan, K., Gilman, M.   +3 more
core   +1 more source

Functional analysis of the homeodomain protein SIX5 [PDF]

Nucleic Acids Research, 2000
SIX5 (previously known as myotonic dystrophy associated homeodomain protein - DMAHP ) is a member of the SIX [ sine oculis homeobox (Drosophila ) homologue ] gene family which encodes proteins containing a SIX domain adjacent to a homeo-domain. To investigate the DNA binding specificities of these two domains in SIX5, they were expressed as GST fusion ...
Harris, S E, Winchester, C L, Johnson, K J   +2 more
openaire   +3 more sources

Vsx2 controls eye organogenesis and retinal progenitor identity via homeodomain and non-homeodomain residues required for high affinity DNA binding. [PDF]

PLoS Genetics, 2012
The homeodomain and adjacent CVC domain in the visual system homeobox (VSX) proteins are conserved from nematodes to humans. Humans with missense mutations in these regions of VSX2 have microphthalmia, suggesting both regions are critical for function ...
Changjiang Zou, Edward M Levine
doaj   +1 more source

Chromatin status and transcription factor binding to gonadotropin promoters in gonadotrope cell lines. [PDF]

, 2017
BackgroundProper expression of key reproductive hormones from gonadotrope cells of the pituitary is required for pubertal onset and reproduction. To further our understanding of the molecular events taking place during embryonic development, leading to ...
Brayman, Melissa J, Hoffmann, Hanne M, Iyer, Anita K, Mellon, Pamela L, Ngo, Cindy, Sunshine, Mary Jean, Xie, Huimin   +6 more
core   +3 more sources

Homeodomain-interacting Protein Kinases, a Novel Family of Co-repressors for Homeodomain Transcription Factors [PDF]

Journal of Biological Chemistry, 1998
A novel family of cofactors that differentially interact with homeoproteins have been identified via a yeast two-hybrid screen. The proteins contain a conserved protein kinase domain that is separated from a domain that interacts with homeoproteins and hence are termed homeodomain-interacting protein kinases (HIPKs): HIPK1, HIPK2, and HIPK3.
Y H, Kim, C Y, Choi, S J, Lee, M A, Conti, Y, Kim   +4 more
openaire   +2 more sources

Expression of a truncated ATHB17 protein in maize increases ear weight at silking. [PDF]

PLoS ONE, 2014
ATHB17 (AT2G01430) is an Arabidopsis gene encoding a member of the α-subclass of the homeodomain leucine zipper class II (HD-Zip II) family of transcription factors.
Elena A Rice, Abha Khandelwal, Robert A Creelman, Cara Griffith, Jeffrey E Ahrens, J Philip Taylor, Lesley R Murphy, Siva Manjunath, Rebecca L Thompson, Matthew J Lingard, Stephanie L Back, Huachun Larue, Bonnie R Brayton, Amanda J Burek, Shiv Tiwari, Luc Adam, James A Morrell, Rico A Caldo, Qing Huai, Jean-Louis K Kouadio, Rosemarie Kuehn, Anagha M Sant, William J Wingbermuehle, Rodrigo Sala, Matt Foster, Josh D Kinser, Radha Mohanty, Dongming Jiang, Todd E Ziegler, Mingya G Huang, Saritha V Kuriakose, Kyle Skottke, Peter P Repetti, T Lynne Reuber, Thomas G Ruff, Marie E Petracek, Paul J Loida   +36 more
doaj   +1 more source

BMP2 commitment to the osteogenic lineage involves activation of Runx2 by DLX3 and a homeodomain transcriptional network

, 2006
Several homeodomain (HD) proteins are critical for skeletal patterning and respond directly to BMP2 as an early step in bone formation. RUNX2, the earliest transcription factor proven essential for commitment to osteoblastogenesis, is also expressed in ...
Aberg, Acampora, Afzal, Amjad Javed, Andre J. van Wijnen, Aronow, Bae, Balint, Banerjee, Banerjee, Beanan, Bendall, Bryan, Cheng, Choi, Depew, Depew, Drissi, Drissi, Ducy, Ferrari, Fujita, Gary S. Stein, Gaur, Ghoul-Mazgar, Harris, Hassan, Hoffmann, Ichida, Ishii, Jane B. Lian, Janet L. Stein, Kim, Komori, Lallemand, Lee, Lengner, Lengner, Lundberg, Maria I. Morasso, Matthew Mandeville, McKeown, Miyama, Mohammad Q. Hassan, Nakashima, Newberry, Otto, Owen, Park, Pratap, Provot, Rahul S. Tare, Robinson, Robledo, Roca, Rosen, Ryoo, Satokata, Satokata, Semba, Shirakabe, Smith, Stricker, Suk Hee Lee, Ten Dijke, Vaes, van Gurp, Xu, Yoshizawa, Zaidi, Zaidi, Zambotti   +71 more
core   +1 more source

ZINC-FINGER interactions mediate transcriptional regulation of hypocotyl growth in Arabidopsis [PDF]

, 2018
Integration of environmental signals and interactions among photoreceptors and transcriptional regulators is key in shaping plant development. TANDEM ZINC-FINGER PLUS3 (TZP) is an integrator of light and photoperiodic signaling that promotes flowering in
Breton, Ghislain, Chory, Joanne, Davidson, Mhairi L.H., Herzyk, Pawel, Kaiserli, Eirini, Kay, Steve A., Nastase, Ana-Maria, O'Donnell, Liz, Perrella, Giorgio, Pruneda-Paz, Jose L.   +9 more
core   +1 more source

The homeodomain transcription factor Phox2 in the stellate ganglion of the squid Loligo pealei

Biology Open, 2015
Homeodomain transcription factors regulate development of embryos and cellular physiology in adult systems. Paired-type homeodomain genes constitute a subclass that has been particularly implicated in establishment of neuronal identity in the mammalian ...
J. Peter H. Burbach, Anita J. C. G. M. Hellemons, Philip Grant, Harish C. Pant   +3 more
doaj   +1 more source

Oakleaf: an S locus-linked mutation of Primula vulgaris that affects leaf and flower development [PDF]

, 2015
•In Primula vulgaris outcrossing is promoted through reciprocal herkogamy with insect-mediated cross-pollination between pin and thrum form flowers. Development of heteromorphic flowers is coordinated by genes at the S locus.
Anders S, Barrett SCH, David Swarbreck, Dijk W, Ernst A, Ernst A, Ernst A, Garber R, Gemy Kaithakottil, Jinhong Li, Jonathan M. Cocker, Jonathan Wright, Lewis D, Margaret A. Webster, Parkinson J, Passe C, Pellow C, Philip M. Gilmartin, Smith LG, Webster MA   +19 more
core   +1 more source