Results 31 to 40 of about 60,933,508 (232)

Interleukin 27 is a novel cytokine with anti-inflammatory effects against spondyloarthritis through the suppression of Th17 responses

Frontiers in Immunology, 2023
IntroductionSpondylarthritis (SpA) development in HLA-B27/human β2-microglobulin transgenic rat (B27-rat) is correlated with altered conventional dendritic cell (cDC) function that promotes an inflammatory pattern of CD4+T cells, including a biased ...
Quentin Jouhault, Quentin Jouhault, Bilade Cherqaoui, Bilade Cherqaoui, Aude Jobart-Malfait, Aude Jobart-Malfait, Simon Glatigny, Simon Glatigny, Marc Lauraine, Marc Lauraine, Audrey Hulot, Audrey Hulot, Guillaume Morelle, Guillaume Morelle, Benjamin Hagege, Benjamin Hagege, Kétia Ermoza, Kétia Ermoza, Ahmed El Marjou, Brigitte Izac, Benjamin Saintpierre, Franck Letourneur, Séverine Rémy, Ignacio Anegon, Marie-Christophe Boissier, Gilles Chiocchia, Gilles Chiocchia, Gilles Chiocchia, Maxime Breban, Maxime Breban, Maxime Breban, Luiza M. Araujo, Luiza M. Araujo   +32 more
doaj   +1 more source

Pro-inflammatory signaling by IL-10 and IL-22: bad habit stirred up by interferons? [PDF]

, 2013
Interleukin (IL)-10 and IL-22 are key members of the IL-10 cytokine family that share characteristic properties such as defined structural features, usage of IL-10R2 as one receptor chain, and activation of signal transducer and activator of ...
Heiko Mühl, Heiko eMühl, Mühl, Heiko
core   +1 more source

Immunological Aspects of ELISA Positive PCR Negative Newly Diagnosed Hepatitis C Patients in Kirkuk Province

Al-Kitab Journal for Pure Sciences, 2022
This study was conducted in Kirkuk city from June 2018 to March 2019. The number of hepatitis patient understudy were 40 newly diagnosed hepatitis C whose ages were between 20-75 years old.
Muhannad Abdullah Al-Azzawy
doaj   +1 more source

Shifting the paradigm in bipolar disorder: moving beyond conventional inflammatory markers to novel EBI3-containing heterodimeric cytokines

Frontiers in Psychiatry
BackgroundResearch shows immune dysregulation in bipolar disorder (BD), but clinical heterogeneity and variable treatment responses persist around inflammatory markers like IL-6, TNF-α, and CRP.
Junfang Wu, Meixia Li, Long Cheng, Jun Chai, Shanshan Zhai   +4 more
doaj   +1 more source

The regulation of CD4+ T cell responses during protozoan infections.

Frontiers in Immunology, 2014
CD4+ T cells are critical for defence against protozoan parasites. Intracellular protozoan parasite infections generally require the development of a Th1 cell response, characterised by the production of IFNγ and TNF that are critical for the generation ...
Christian eEngwerda, Susanna S Ng, Patrick T Bunn   +2 more
doaj   +1 more source

Association of IL‐17 and IL‐27 polymorphisms with susceptibility to recurrent pregnancy loss and pre‐eclampsia: A systematic review and meta‐analysis

Immunity, Inflammation and Disease, 2023
Objective Recurrent pregnancy loss (RPL) and pre‐eclampsia (PE) are immune‐related pregnancy complications that have been linked to CD4+ T cells and their cytokines, which can be influenced by genetic polymorphisms.
Yue Ma, Mingyue Ma, Shenglong Ye, Yuanying Liu, Xueqing Zhao, Yongqing Wang   +5 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

A network of IL-27.

, 2014
A network showing how IL-27 affects the immune response to tumor cells. CD8+ T cells are activated by P1A antigen from tumor cells as well as by IL-27 which is secreted by tumor cells.
Xue-Feng Bai (333686), Kang-Ling Liao (535938), Avner Friedman (54903)   +2 more
core   +1 more source

Interleukin-27 Early Impacts Leishmania infantum Infection in Mice and Correlates with Active Visceral Disease in Humans

Frontiers in Immunology, 2016
The complexity of Leishmania-host interactions, one of the main leishmaniasis issues, is yet to be fully understood. We detected elevated IL-27 plasma levels in European patients with active visceral disease caused by Leishmania infantum, which returned ...
Begoña Pérez-Cabezas, Pedro Cecílio, Ana luisa Robalo, Ricardo Silvestre, Ricardo Silvestre, Eugenia Carrillo, Javier Moreno, Juan V. San Martín, Rita Vasconcellos, Anabela Cordeiro-da-Silva, Anabela Cordeiro-da-Silva   +10 more
doaj   +1 more source

Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan, Michael Abele, Calogero Virgone, Michaela Kuhlen, Ricardo Lopez‐Almarez, Tal Ben‐Ami, Ewa Bien, Maja Cesen, Malgorzata A. Krawczyk, Andrea Ferrari, Gianni Bisogno, Yves Reguerre, Dominik T. Schneider, Louise Galmiche, Jorg Fuchs, Sarah Braungart, Bilgehan Yalcin, Ines B. Brecht, Daniel Orbach   +18 more
wiley   +1 more source