Results 71 to 80 of about 60,933,508 (232)

The cytokine IL-27 reduces inflammation and protects photoreceptors in a mouse model of retinal degeneration

Journal of Neuroinflammation, 2022
Background Retinal degenerative diseases are a group of conditions characterized by photoreceptor death and vision loss. Excessive inflammation and microglial activation contribute to the pathology of retinal degenerations and a major focus in the field ...
Andrea Nortey, Kimberly Garces, Tal Carmy-Bennun, Abigail S. Hackam   +3 more
doaj   +1 more source

Biphasic Clinical Course of Pediatric Cytomegalovirus‐Associated Immune Thrombocytopenia: Early Poor Treatment Response but Favorable Long‐Term Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cytomegalovirus (CMV) is a recognized trigger of immune thrombocytopenia (ITP); however, its incidence and impact on disease course in children remain controversial. Therefore, we aimed to characterize the clinical course of pediatric patients with CMV‐associated ITP.
Oded Gilad, Ohad Atia, Osama Tanous, Dafna Brik Simon, Michal Dvori, Miriam Cohen, Tracie A. Goldberg, Efraim Bilavsky, Joanne Yacobovich, Orna Steinberg‐Shemer   +9 more
wiley   +1 more source

Bone Mineral Density After Contemporary Treatment for Acute Lymphoblastic Leukaemia: A Matched Cross‐Sectional Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Reduced bone mineral density (BMD) has been reported in survivors of childhood and young adult acute lymphoblastic leukaemia (ALL); however, data from cohorts treated with contemporary protocols and including matched controls remain limited.
Karen Schow Jensen, Mette Tiedemann Skipper, Niels Holtum Birkebæk, Kjeld Schmiegelow, Thomas Leth Frandsen, Bente Langdahl, Rikke Beck Jensen, Asger Roer Pedersen, Christian Mølgaard, Liv Andrés‐Jensen, Birgitte Klug Albertsen   +10 more
wiley   +1 more source

IL-27: a double agent in the IL-6 family [PDF]

, 2018
Summary The cytokine interleukin (IL)-6 is a major therapeutic target for the treatment of various inflammatory and autoimmune diseases.
D G Hill, Jones, Simon, G W Jones, S A Jones, Hill, David, A Cardus, Figueras, Ana Cardus, Jones, Gareth, Cardus Figueras, Ana   +8 more
core   +1 more source

Chemotherapy for Spinal Cord Intramedullary Pediatric Low‐Grade Glioma—A Systematic Literature Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko, Segev Gabay, Jonathan Roth, Amit Ringel, Rina Dvir, Shlomi Constantini   +5 more
wiley   +1 more source

O papel da Interleucina 27 (IL-27) na replicação da Leishmania em Macrófagos

, 2012
Os parasitos do gênero Leishmania são protozoários que se replicam em macrófagos após a infecção do hospedeiro vertebrado pelo vetor flebotomíneo.
Regis, Eduardo Garcia Necco Peixoto
core  

IL-Info 27

, 1988
IL-INFO 27 IL-Info / Institut für Leichte Flächentragwerke (-) IL-Info 1-18 (1969 [6.-8-]) ( - ) IL-Info 1 (1.1970 eng) (-) IL-Info 2 (2. 1971 eng) (-) IL-Info 3 (3. 1971 eng) (-) IL-Info 4 (4. 1971 eng) (-) IL-Info 5
Universität Stuttgart. Institut für Leichte Flächentragwerke
core   +3 more sources

IL-27 as effector molecule in viral infections and immunity

Инфекция и иммунитет
Interleukin-27 (IL-27) is a cytokine with multifaceted effects on immune responses. It is composed of two subunits: IL-27p28 и EBI3. The receptor complex for IL-27 consists of the heterodimeric IL-27R, which includes IL-27Rα and gp130.
Zoya R. Korobova, N. A. Arsentieva, A. A. Totolian   +2 more
doaj   +1 more source

Interleukin-27 decreases ghrelin production through signal transducer and activator of transcription 3—mechanistic target of rapamycin signaling

Acta Pharmaceutica Sinica B, 2020
Interleukin-27 (IL-27), a heterodimeric cytokine, plays a protective role in diabetes. Ghrelin, a gastric hormone, provides a hunger signal to the central nervous system to stimulate food intake.
Heng Zhang, Qingjie Li, Yuxin Teng, Yubi Lin, Shaojian Li, Tingfeng Qin, Linxi Chen, Jiana Huang, Hening Zhai, Quan Yu, Geyang Xu   +10 more
doaj   +1 more source

Exercise Capacity, Physical Activity, Fatigue, and Neurocognitive Function in Adult Survivors of Childhood Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess, Gustaf Glavå, Simon Skau, Hans‐Georg Kuhn, Maria Bäck, Marianne Jarfelt   +5 more
wiley   +1 more source