Results 211 to 220 of about 2,017,899 (336)

Correlation analysis of TGF-β1, MMP-9, TIMP-1, IL-1, IL-4, IL-6, IL-17, and TNF-α in refractory chronic rhinosinusitis: A retrospective study

, 2022
Wulin Wen, Simin Zhu, Ruixia Ma, Lixin Wang, Xueliang Shen, Yongchun Li, Ningyu Feng, Le Wang, Ming Liu, Lina Xie, Xueqiang Zhang   +10 more
openalex   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Association of maternal IL-2, IL-4, and IL-13 with intrauterine growth restriction and umbilical artery doppler: a case-control study. [PDF]

Rev Bras Ginecol Obstet
Afshar BM, Dargahi R, Tabrizian S, Jafarzadeh M, Sarkhani S, Sarkhani N.   +5 more
europepmc   +1 more source

CONCORSO PUBBLICO PER ESAMI PER LA COPERTURA DI N. 6 POSTI A TEMPO PIENO ED INDETERMINATO DI ISTRUTTORE AMMINISTRATIVO - AREA DEGLI ISTRUTTORI, di cui: n. 2 posti con riserva prioritaria ai militari volontari delle forze armate congedati senza demerito ex art. 1014 D.lgs. 66/2010 e n. 1 posto con riserva a favore degli operatori volontari che hanno concluso il servizio civile universale ai sensi dell'art.18, comma 4, D.lgs. 40/2017. - Lazio - Comune di Civitavecchia

Easy Quizzz
openalex   +1 more source

Interleukin (IL)-4–independent Induction of Immunoglobulin (Ig)E, and Perturbation of  T Cell Development in Transgenic Mice Expressing IL-13 [PDF]

, 1998
Claire Emson, Sarah E. Bell, Alison Jones, William Wisden, Andrew N. J. McKenzie   +4 more
openalex   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Targeting the IL-4/IL-4R Axis in Th2 Inflammatory Diseases: A Review of Clinical Efficacy and Safety. [PDF]

J Inflamm Res
Li W.
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Histamine affects STAT6 phosphorylation via its effects on IL-4 secretion: Role of H1 receptors in the regulation of IL-4 production

, 2006
Geetanjali Kharmate, Zhongfeng Liu, Eric Patterson, Manzoor M. Khan   +3 more
openalex   +2 more sources

NF‐κB‐dependent IL‐8 induction by prostaglandin E₂ receptors EP₁ and EP₄ [PDF]

, 2012
Frank Neuschäfer‐Rube, Andrea Pathe‐Neuschäfer‐Rube, Stefan Hippenstiel, Michael Kracht, GP Püschel   +4 more
openalex   +1 more source