Results 201 to 210 of about 2,017,899 (336)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

IL-4 variant and school mouse exposure increases asthma morbidity in urban schoolchildren. [PDF]

J Allergy Clin Immunol
Ruran HB, Jung YS, Chen Q, Nadeau K, Phipatanakul W, Chatila TA.   +5 more
europepmc   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

IL-4/Nanohydroxyapatite Codelivery in a Dual-Bionic Scaffold: Design and Immunomodulatory Endogenous Osteogenesis Mechanism. [PDF]

ACS Appl Mater Interfaces
Wang FZ, Yu Y, Soh HY, Liu S, Hu LH, Tang ZN, Zhang WB, Peng X.   +7 more
europepmc   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Dermal fibroblasts respond to IL-4 and IL-13 and promote T cell recruitment in atopic dermatitis. [PDF]

J Clin Invest
Numata T, Shia M, Nakamura Y, Li F, Chan H, Nakatsuji T, Cavagnero KJ, Simmons J, Li H, Joshi AA, Palomo-Irigoyen M, Gallo RL.   +11 more
europepmc   +1 more source

Phage display selection of peptides that home to atherosclerotic plaques: IL‐4 receptor as a candidate target in atherosclerosis [PDF]

, 2008
Hai-Yan Hong, Hwa Young Lee, Wonjung Kwak, Jeongsoo Yoo, Moon‐Hee Na, In Seop So, Tae‐Hwan Kwon, Heon‐Sik Park, Seung Huh, Goo Taeg Oh, Ick Chan Kwon, In‐San Kim, Byung‐Heon Lee   +12 more
openalex   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

TGF-β and IL-4 + IL-13 induce neuroplasticity in an <i>in vitro</i> model of hPSC-derived sensory neurons. [PDF]

Front Immunol
Koster CS, Bos IST, Lavitola C, Balogh M, Melgert BN, Gosens R.   +5 more
europepmc   +1 more source

Investigation of the interleukin (IL)‐4/IL‐4 receptor system in promyelocytic leukaemia PLB‐985 cells during differentiation toward neutrophil‐like phenotype: mechanism involved in IL‐4‐induced SOCS3 protein expression [PDF]

, 2007
Claude Ratthé, Denis Girard
openalex   +1 more source