Results 51 to 60 of about 2,073 (211)
ChemPhotoChem, Volume 10, Issue 10, October 2026.Once regarded as highly reactive and difficult‐to‐control intermediates, monosaccharide‐derived radicals have emerged as powerful tools for selective synthesis. This review highlights how modern photocatalytic strategies enable the controlled generation of these radicals and their highly regio‐ and stereoselective transformation into structurally ...
Corentin Lefebvre, Norbert Hoffmann
wiley +1 more source
Gold nanoparticles are suitable cores for building tunable iminosugar multivalency† [PDF]
RSC Advances, 2015 The first example of iminosugars multimerization based on gold nanoparticle cores was achieved by a straightforward synthetic strategy based on the use of simple glycosides of α-d-mannose or β-d-glucose to modulate the density of biologically active ...
C. Matassini +7 more
doaj +1 more source
Retro‐Hetero‐Michael Addition Strategies in Organic Synthesis
European Journal of Organic Chemistry, Volume 29, Issue 32, 24 August 2026.In this review, synthetic approaches to carbo‐ and heterocyclic compounds, including natural products, published in the last 15 years (2011–2025) which have either relied upon or included a retro‐hetero‐Michael addition step at any stage are discussed.
Dina Scarpi, Ernesto G. Occhiato
wiley +1 more source
A complete synthesis of an N-spirofused iminosugar from L-xylose; a potential cholinesterase inhibitor for treatment of Alzheimer’s disease [PDF]
, 2022 In this bachelor’s project we present a complete synthesis of an N-spirofused iminosugar II with a stable positive charge on the spirocyclic nitrogen atom that together with the hydroxyl groups are expected to establish interactions with the residues in ...
Sandvik, Mathias +2 more
core
Chemistry – A European Journal, Volume 32, Issue 29, 7 August 2026.A series of structurally diverse exoglycals was synthesized using a modified Julia‐olefination approach from sugar‐derived precursors. These glycosidase transition‐state mimics were further diversified via CuAAC chemistry to yield triazole‐conjugated analogues.
Elisa Ospanow +2 more
wiley +1 more source
Synthetic Ligands of Myeloid C‐Type Lectin Receptors
ChemBioChem, Volume 27, Issue 13, 14 July 2026.Binding of ligands to C‐type lectin receptors (CLRs) on myeloid cells can lead to an array of cellular responses. Exploitation of these receptors for therapeutic purposes requires high‐affinity ligands. This review surveys the diversity of synthetic ligands of myeloid CLRs in the context of binding, signaling, and downstream effects, as well as ...
James Suri, Bernd Lepenies
wiley +1 more source
, 2016 Correction to “Topological Effects and Binding Modes Operating with Multivalent Iminosugar-Based Glycoclusters and ...
Karim El Kirat (1812493) +9 more
core +1 more source
MoleculesInhibition of glycoside hydrolases has widespread application in the treatment of diabetes. Based on our previous findings, a series of dihydrofuro[3,2-b]piperidine derivatives was designed and synthesized from D- and L-arabinose.
Haibo Wang +6 more
doaj +1 more source
European Journal of Organic Chemistry, Volume 29, Issue 24, 23 June 2026.Chiral tri‐ and pentahydroxy spirocyclopentane‐indolizidines were synthesized using lithium diisopropylamide “LDA” promoted diallylation and tetrahydrofuran “THF” ring‐opening in a one‐pot procedure as a key step. The sequence leading to the targeted hydroxy‐spiroindolizidines was achieved by cis‐dihydroxylation followed by reduction of the enamine and
Paula Fraňová +6 more
wiley +1 more source
, 2016 Severity of histological lesions in HE stained tissues from iminosugar treated guinea pigs, challenged with EBOV.
Irene Taylor (111066) +13 more
core +1 more source