Results 11 to 20 of about 29,641 (245)
The dendritic cell side of the immunological synapse
Biomolecular Concepts, 2016 Immune responses are initiated by the interactions between antigen-presenting cells (APCs), such as dendritic cells (DCs), with responder cells, such as T cells, via a tight cellular contact interface called the immunological synapse.
Ilse Dingjan +2 more
exaly +2 more sources
CD28 and chemokine receptors: Signalling amplifiers at the immunological synapse [PDF]
Frontiers in Immunology, 2022 T cells are master regulators of the immune response tuning, among others, B cells, macrophages and NK cells. To exert their functions requiring high sensibility and specificity, T cells need to integrate different stimuli from the surrounding ...
Barbara Molon +5 more
doaj +2 more sources
HIV-1 Virological Synapse is not Simply a Copycat of the Immunological Synapse
Viruses, 2010 The virological synapse (VS) is a tight adhesive junction between an HIV-infected cell and an uninfected target cell, across which virus can be efficiently transferred from cell to cell in the absence of cell-cell fusion.
Catarina Hioe +2 more
exaly +3 more sources
Kv1.3 palmitoylation regulates spatial distribution and channel removal from the immunological synapse [PDF]
Cellular and Molecular Life SciencesKv1.3 is the main voltage-gated potassium channel in T cells. At the immunological synapse (IS), it sustains Ca2⁺ signaling and facilitates T cell activation.
María Navarro-Pérez +5 more
doaj +3 more sources
Comparative anatomy of phagocytic and immunological synapses [PDF]
Frontiers in Immunology, 2016 The generation of phagocytic cups and immunological synapses are crucial events of the innate and adaptive immune responses, respectively. They are triggered by distinct immune receptors and performed by different cell types.
Florence eNiedergang +2 more
doaj +4 more sources
Connexin-Mediated Signaling at the Immunological Synapse [PDF]
International Journal of Molecular Sciences, 2020 Flavio Salazar-Onfray +2 more
exaly +2 more sources
Despite disorganized synapse structure, Th2 cells maintain directional delivery of CD40L to antigen-presenting B cells. [PDF]
PLoS ONE, 2017 Upon recognition of peptide displayed on MHC molecules, Th1 and Th2 cells form distinct immunological synapse structures. Th1 cells have a bull's eye synapse structure with TCR/ MHC-peptide interactions occurring central to a ring of adhesion molecules ...
Jennifer L Gardell, David C Parker
doaj +1 more source
Cytotoxic immunological synapses [PDF]
Immunological Reviews, 2010 Summary: One of the most fundamental activities of the adaptive immune system is to kill infected cells and tumor cells. Two distinct pathways mediate this process, both of which are facilitated by a cytotoxic immunological synapse. While traditionally thought of as innate immune cells, natural killer (NK) cells are now appreciated to have the ...
Dustin, M, Long, E
openaire +3 more sources
Frontiers in Cell and Developmental Biology, 2021 Natural killer (NK) cells are innate lymphoid cells, which play key roles in elimination of virally infected and malignant cells. The balance between activating and inhibitory signals derived from NK surface receptors govern the NK cell immune response ...
Aviad Ben-Shmuel +3 more
doaj +1 more source
Frontiers in Immunology, 2022 Hemichannels (HCs)/gap junctions (GJs) and immunoglobulin (Ig)-like domain-containing proteins (IGLDCPs) are involved in the innate–adaptive immune response independently.
Jiang-Hui Meng +8 more
doaj +1 more source