Results 11 to 20 of about 226,715 (279)
Cells, 2019 The immune system is a fundamental part of the tumor microenvironment. In particular, cytotoxic lymphocytes, such as cytolytic T cells and natural killer cells, control tumor growth and disease progression by interacting and eliminating tumor cells.
Hannah Wurzer +2 more
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Signaling and the immunological synapse
, 2010 This chapter deals with T cell activation and immunological synapses. It begins with a brief summary of T cell biology to put a discussion of immune synapses into a broader context because the study of immunological synapses addresses issues pertaining ...
Andrey S. Shaw +3 more
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Signaling amplification at the immunological synapse [PDF]
, 2009 The immunological synapse is a dynamic structure, formed between a T cell and one or more antigen-presenting cells, characterized by lipid and protein segregation, signaling compartmentalization, and bidirectional information exchange through soluble and
CONTENTO, RITA LUCIA +8 more
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Cell polarisation and the immunological synapse [PDF]
Current Opinion in Cell Biology, 2013 Directed secretion by immune cells requires formation of the immunological synapse at the site of cell-cell contact, concomitant with a dramatic induction of cell polarity. Recent findings provide us with insights into the various steps that are required
Griffiths, Gillian M, Angus, Karen L
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Geometrically repatterned immunological synapses uncover formation mechanisms. [PDF]
PLoS Computational Biology, 2006 The interaction of T cells and antigen-presenting cells is central to adaptive immunity and involves the formation of immunological synapses in many cases.
Marc Thilo Figge, Michael Meyer-Hermann
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, 2015 International audienceImmunological synapses are dynamically organised cell–cell interfaces formed between cells of the immune system. Different types of immunological synapses lead to distinct functional outcomes.
Jérôme Bouchet +5 more
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HIV-1 Virological Synapse is not Simply a Copycat of the Immunological Synapse
Viruses, 2010 The virological synapse (VS) is a tight adhesive junction between an HIV-infected cell and an uninfected target cell, across which virus can be efficiently transferred from cell to cell in the absence of cell-cell fusion.
Michael L Dustin, Gaia Vasiliver-Shamis
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Action and Traction: Cytoskeletal Control of Receptor Triggering at the Immunological Synapse
Frontiers in Immunology, 2016 It is well known that F-actin dynamics drive micron-scale cell shape changes required for migration and immunological synapse formation. In addition, recent evidence points to a more intimate role for the actin cytoskeleton in promoting T cell activation.
Jänis Burkhardt, William Comrie
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Kv1.3 palmitoylation regulates spatial distribution and channel removal from the immunological synapse [PDF]
Cellular and Molecular Life SciencesKv1.3 is the main voltage-gated potassium channel in T cells. At the immunological synapse (IS), it sustains Ca2⁺ signaling and facilitates T cell activation.
María Navarro-Pérez +5 more
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The immunological synapse [PDF]
Cancer Immunology Research, 2003 Udgivelsesdato: 2003-nullThe induction of a proper adaptive immune response is dependent on the correct transfer of information between antigen-presenting cells (APCs) and antigen-specific T cells.
Klemmensen, Thomas +2 more
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