Results 51 to 60 of about 114,851,153 (292)

Effect of in Vitro Simulated Digestion of Rice Bran Protein Structure and Immune Activity of Its Digestion Products

open access: yesShipin gongye ke-ji
This study aimed to investigate the structural changes of rice bran protein during gastrointestinal digestion and the immunomodulatory activity of its digestive products. Rice bran protein (RBP) was used as the raw material.
Qiuxing CHEN   +3 more
doaj   +1 more source

Simulated gastrointestinal digestion and in vitro colonic fermentation of carob polyphenols: Bioaccessibility and bioactivity

open access: yesLWT, 2020
Abstract Carob is a well-known tree for its nutritional and health-promoting edible pods due to its high phenolic contents. It was aimed to investigate: 1) carob phenolic profiles; soluble free, soluble conjugated and bound, 2) bioaccesibility of those phenolics during simulated gastrointestinal digestions, plus in vitro fecal fermentations, 3) their
Yasmina Ait Chait   +3 more
openaire   +1 more source

Cancer‐Associated BCL‐2 Mutants Reveal Mechanisms Towards Venetoclax Resistance

open access: yesAdvanced Science, EarlyView.
Venetoclax (VEN) resistance in chronic lymphocytic leukemia arises from diverse BCL2 mutations. We map mechanisms contributing to VEN resistance across common BCL‐2 variants. G101V and D103Y reduce drug binding and increase sequestration of pro‐apoptotic proteins. V156D blocks VEN allosterically.
Jonas Aufdermauer   +9 more
wiley   +1 more source

Gold Nanoparticles Synthesized with Natural Compounds: Assesment of Antioxidant Activity After In Vitro Digestion

open access: yesStudia Universitatis Babes-Bolyai Chemia
Currently, gold nanoparticles (GNPs) are considered an ideal delivery system due to their physiological stability, high bioactivity, and controlled release of biological component.
Dalina Diana ZUGRAVU (POP)   +5 more
doaj   +1 more source

Atividade antioxidante e crioconcentração dos compostos bioativos do extrato aquoso de erva-mate (Ilex paraguariensis A. St. Hil.) [PDF]

open access: yes, 2015
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Agrárias, Programa de Pós-Graduação em Ciência dos Alimentos, Florianópolis, 2015.A atividade antioxidante do extrato aquoso de erva-mate está relacionada principalmente ...
Boaventura, Brunna Cristina Bremer
core  

Heavy metal bioavailability and bioaccessibility in soil [PDF]

open access: yes, 2009
This chapter considers the use of a variety of approaches to assess either the bioavailability or the bioaccessibility of metals in soil. The bioavailability of metals from soils is considered with respect to a series of single-extraction methods ...
Dean, John, John Richard Dean
core   +1 more source

O‐GlcNAcylation Regulation of SNAP29‐Dependent Autophagy Activation Dictates Chemoresistance in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
Model illustrating the proposed mechanism by which chemotherapy‐induced downregulation of OGT disrupts SNAP29 O‐GlcNAcylation, promoting STX17‐SNAP29‐VAMP8 SNARE complex assembly and protective autophagy, leading to chemoresistance, which in turn establishes a feedforward loop to perpetuate drug tolerance.
Liang Tang   +9 more
wiley   +1 more source

Preparation of Ginger Peel Polysaccharide-zinc Complex and in Vitro Simulated Digestion

open access: yesShipin gongye ke-ji, 2022
In this study, ginger peel polysaccharide were combined with zinc sulfate, and its preparation process was optimized by single factor and response surface experiments with the chelation rate as the index.
Wenwen LI   +5 more
doaj   +1 more source

Assessment of the bioaccessibility of phenolics from Australian grown lettuces by in vitro simulated gastrointestinal digestion and colonic fermentation

open access: yes, 2023
Assessment of the bioaccessibility of phenolics from Australian grown lettuces by in vitro simulated gastrointestinal digestion and colonic ...
H Wu (7724324)   +7 more
core  

Hypomethylation of GNA15 Promotes Pancreatic Ductal Adenocarcinoma Progression and Macrophage M2 Polarization via STAT3‐CXCL8 Axis

open access: yesAdvanced Science, EarlyView.
A schematic model summarizing GNA15's mechanism in mediating macrophage M2 polarization and Gemcitabine resistance. ABSTRACT The complexity of pancreatic ductal adenocarcinoma (PDAC) progression, coupled with the lack of effective immunotherapy, underscores the imperative to deepen our understanding of its mechanisms and identify suitable immune ...
Weihui Guo   +8 more
wiley   +1 more source

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