Interleukin-31, Interleukin-31RA, and OSMR Expression Levels in Post-burn Hypertrophic Scars [PDF]
Journal of Pathology and Translational Medicine, 2018 Background Although several studies have shown the role of interleukin-31 (IL-31) and its receptors in inducing pruritus in certain skin disorders, knowledge of its role in post-burn hypertrophic scars is insufficient.
Mi Young Lee +4 more
doaj +1 more source
Role of IL-33 in inflammation and disease [PDF]
, 2011 Interleukin (IL)-33 is a new member of the IL-1 superfamily of cytokines that is expressed by mainly stromal cells, such as epithelial and endothelial cells, and its expression is upregulated following pro-inflammatory stimulation.
Miller, Ashley M.
core +3 more sources
Acta Dermato-Venereologica, 2017 A recent study suggests that interleukin-31 (IL-31) exerts its effect via indirect mechanisms rather than through direct stimulation of cutaneous nerves.
Tsugunobu Andoh +2 more
doaj +1 more source
IL-31 associated with coronary artery lesion formation in Kawasaki disease. [PDF]
PLoS ONE, 2014 Kawasaki disease (KD) is known to be associated with T help (Th) 2 reaction and subsequently allergic diseases. Interleukin-31 (IL-31) has also been reported to be involved in Th2 mediated diseases such as allergic diseases. However, the role of IL-31 in
Wan-Ning Tseng +5 more
doaj +1 more source
Actas Dermo-Sifiliográficas, 2022 Interleukin 31 (IL-31) is a neurocytokine that stimulates sensory neurons involved in pruritus. It contributes to skin barrier inflammation, dysfunction, and remodeling.
E. Serra-Baldrich +2 more
doaj +1 more source
Long-term study of the impact of methotrexate on serum cytokines and lymphocyte subsets in patients with active rheumatoid arthritis: correlation with pharmacokinetic measures [PDF]
, 2016 Objective To describe changes in immune parameters observed during long-term methotrexate (MTX) therapy in patients with active rheumatoid arthritis (RA) and explore correlations with simultaneously measured MTX pharmacokinetic (PKC) parameters ...
Hamilton, Robert +3 more
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Eosinophils are a Major Source of Interleukin-31 in Bullous Pemphigoid
Acta Dermato-Venereologica, 2018 Bullous pemphigoid (BP) is characterized by substantial skin and blood eosinophilia as well as intensive pruritus. Since the pruritogenic cytokine interleukin (IL)-31 is increased in inflammatory skin diseases the aim of this study was to determine ...
Urda Rüdrich +9 more
doaj +1 more source
Profile of Serum Interleukin-31 Levels in Atopic Dermatitis
Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology), 2017 Background: Atopic dermatitis (AD) is a chronic inflammatory skin disorder characterized by pruritic skin lesion. Pathogenesis of AD is not fully understood, but recent studies demonstrate the role of interleukin-31 (IL-31).
Dewi Kusumawati +2 more
doaj +1 more source
Coxiella burnetii Blocks Intracellular Interleukin-17 Signaling in Macrophages [PDF]
, 2018 Coxiella burnetii is an obligate intracellular bacterium and the etiological agent of Q fever. Successful host cell infection requires the Coxiella type IVB secretion system (T4BSS), which translocates bacterial effector proteins across the vacuole ...
Clemente, Tatiana M. +5 more
core +1 more source
A randomised trial of subcutaneous intermittent interleukin-2 without antiretroviral therapy in HIV-infected patients: the UK-Vanguard Study [PDF]
, 2006 Objective: The objective of the trial was to evaluate in a pilot setting the safety and efficacy of interleukin-2 (IL-2) therapy when used without concomitant antiretroviral therapy as a treatment for HIV infection.
Abrams +44 more
core +2 more sources